NR2C2

Description		nuclear receptor subfamily 2 group C member 2
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Nuclear Receptor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Spermatogenesis Nervous System Development Cell Differentiation Intracellular Receptor Signaling Pathway Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Embryonic Development Positive Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of JNK Cascade
Pathways		Nuclear Receptor transcription pathway
Drugs
Diseases
GWAS		Alcohol and nicotine co-dependence ( 22488850) Femur bone mineral density x serum urate levels interaction ( 34046847)
Novel Interacting Genes		1 novel interacting genes: RPL36
Interacting Genes		23 interacting genes: AR CD2AP CDC37 CHUK ESR1 FKBP5 HDAC4 HNF4A HSP90AA1 HSP90AB1 IKBKB ITSN2 JAZF1 KDM1A NR2C1 NR2C2AP PEBP1 RAC1 RXRB TAB1 TAB2 TRAF2 TRIM55
Entrez ID		7182
HPRD ID		03253
Ensembl ID		ENSG00000177463
Uniprot IDs		F2YGU2 P49116
PDB IDs		3P0U 7XV6 7XV8 7XV9 7XVA
Enriched GO Terms of Interacting Partners?		Regulation Of Signal Transduction Non-canonical NF-kappaB Signal Transduction Regulation Of Intracellular Signal Transduction Regulation Of Cell Communication Intracellular Signal Transduction Nuclear Receptor Activity Regulation Of Signaling Canonical NF-kappaB Signal Transduction Intracellular Receptor Signaling Pathway Nuclear Steroid Receptor Activity Intracellular Signaling Cassette Nitric-oxide Synthase Regulator Activity CD40 Receptor Complex Positive Regulation Of Intracellular Signal Transduction Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Protein Modification Process HSP90-CDC37 Chaperone Complex Regulation Of Nitric Oxide Metabolic Process Protein Kinase Binding Scaffold Protein Binding Positive Regulation Of Signal Transduction Steroid Hormone Receptor Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway IkappaB Kinase Activity Rho GDP-dissociation Inhibitor Binding Protein-containing Complex Positive Regulation Of Metabolic Process Positive Regulation Of Cell Communication Positive Regulation Of Signaling Nuclear Receptor-mediated Signaling Pathway Protein Folding Chaperone Complex Cytosol Enzyme Binding Regulation Of Macromolecule Metabolic Process Positive Regulation Of DNA-binding Transcription Factor Activity Positive Regulation Of Nitric Oxide Biosynthetic Process Signal Transduction Involved In Regulation Of Gene Expression Negative Regulation Of Metabolic Process Cytoplasm Positive Regulation Of Nitric Oxide Metabolic Process Regulation Of Innate Immune Response Telomerase Holoenzyme Complex Assembly Regulation Of Immune Response Histone Deacetylase Binding Nucleoplasm Response To External Biotic Stimulus IkappaB Kinase Complex Hormone-mediated Signaling Pathway Dendritic Growth Cone TPR Domain Binding
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