TNFRSF1A and CASP10

  • Number of citations of the paper that reports this interaction (PMID 9045686)
  • 25
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vitro)

TNFRSF1A

CASP10

Gene Name tumor necrosis factor receptor superfamily, member 1A caspase 10, apoptosis-related cysteine peptidase
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs) ( 23648065)
  • Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin) ( 23648065)
  • Multiple sclerosis ( 19525953 21833088)
  • Primary biliary cirrhosis ( 21399635)
Protein-Protein Interactions 60 interactors: ADAM17 ATF6 BAG4 BCL10 CASP10 CASP7 CHUK CLIP3 DAPK1 DAXX ERAP1 ERN1 FANCD2 GNB2L1 GRB2 GYS2 HRG HSP90AA1 HSPA8 IKBKB IKBKG JAK1 JAK2 LTA LTB MADD MAGEH1 MAPK1 MOAP1 MYOC NSMAF PIP4K2B PRDX3 PRKCD PSMD2 PTK2 PTPN11 PTPN6 RASSF1 RIPK1 RIPK2 RIPK3 SGTA SRC STAMBP STAT1 SUMO1 SYK TNF TNFRSF25 TNFSF13 TRADD TRAF1 TRAF2 TRAF3 TRAP1 TRPC4AP UBE2I UBQLN1 UCHL1 30 interactors: BFAR BID CASP1 CASP14 CASP2 CASP3 CASP4 CASP6 CASP7 CASP8 CASP8AP2 CASP9 CCAR1 CFLAR DEDD DEDD2 DSP ECE2 FADD NFKBIL1 OIP5 PHF20L1 POLR2A PRDX6 RB1 RIOK3 RYBP TNFRSF1A TRAF1 XIAP
Entrez ID 7132 843
HPRD ID 01861 03458
Ensembl ID ENSG00000067182 ENSG00000003400
Uniprot IDs J9PH39 P19438 Q92851
PDB IDs 1EXT 1FT4 1ICH 1NCF 1TNR
Enriched GO Terms of Interacting Partners?
Tagcloud ?
casp3  cl  coincided  corpora  cyclic  disaggregation  estrous  extrinsic  fas  fasl  faslg  fos  ifng  ifngamma  jun  lutea  luteal  luteolysis  luteolytic  p4  pgf2alpha  postmortem  pregnancy  proportions  tnfa  tnfr2  viable 
arginine  bcl3  dap1  derepression  epigenetic  epigenetically  governs  hdac1  hodgkin  hoxa5  hrk  indirectly  lymphoma  master  methyltransferase  offer  p52  polycomb  prc2  prmt5  rb1  rbl2  reactivation  repression  repressor  retinoblastoma  tp53k372  trigger  turn 
Tagcloud (Difference) ?
casp3  cl  coincided  corpora  cyclic  disaggregation  estrous  extrinsic  fas  fasl  faslg  fos  ifng  ifngamma  jun  lutea  luteal  luteolysis  luteolytic  p4  pgf2alpha  postmortem  pregnancy  proportions  tnfa  tnfr2  viable 
arginine  bcl3  dap1  derepression  epigenetic  epigenetically  governs  hdac1  hodgkin  hoxa5  hrk  indirectly  lymphoma  master  methyltransferase  offer  p52  polycomb  prc2  prmt5  rb1  rbl2  reactivation  repression  repressor  retinoblastoma  tp53k372  trigger  turn 
Tagcloud (Intersection) ?