TNFRSF1A and UCHL1

  • Number of citations of the paper that reports this interaction (PMID 24980434)
  • 1
  • Data Source:
  • BioGRID (enzymatic study)

TNFRSF1A

UCHL1

Gene Name tumor necrosis factor receptor superfamily, member 1A ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs) ( 23648065)
  • Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin) ( 23648065)
  • Multiple sclerosis ( 19525953 21833088)
  • Primary biliary cirrhosis ( 21399635)
Protein-Protein Interactions 60 interactors: ADAM17 ATF6 BAG4 BCL10 CASP10 CASP7 CHUK CLIP3 DAPK1 DAXX ERAP1 ERN1 FANCD2 GNB2L1 GRB2 GYS2 HRG HSP90AA1 HSPA8 IKBKB IKBKG JAK1 JAK2 LTA LTB MADD MAGEH1 MAPK1 MOAP1 MYOC NSMAF PIP4K2B PRDX3 PRKCD PSMD2 PTK2 PTPN11 PTPN6 RASSF1 RIPK1 RIPK2 RIPK3 SGTA SRC STAMBP STAT1 SUMO1 SYK TNF TNFRSF25 TNFSF13 TRADD TRAF1 TRAF2 TRAF3 TRAP1 TRPC4AP UBE2I UBQLN1 UCHL1 27 interactors: ADRA2A ADRA2B ADRA2C ADRB2 CBX1 CDKN1B COPS5 EGFR HSP90AA1 HSPA8 LAMP2 NCAM1 NEDD8 PARK2 PLA2G2A RANBP9 SMN1 TERF2IP TINF2 TNFRSF1A TRIM54 TRIM63 UBC UBE2I USP15 USP21 USP28
Entrez ID 7132 7345
HPRD ID 01861 01877
Ensembl ID ENSG00000067182 ENSG00000154277
Uniprot IDs J9PH39 P19438 P09936
PDB IDs 1EXT 1FT4 1ICH 1NCF 1TNR 2ETL 2LEN 3IFW 3IRT 3KVF 3KW5 4DM9
Enriched GO Terms of Interacting Partners?
Tagcloud ?
casp3  cl  coincided  corpora  cyclic  disaggregation  estrous  extrinsic  fas  fasl  faslg  fos  ifng  ifngamma  jun  lutea  luteal  luteolysis  luteolytic  p4  pgf2alpha  postmortem  pregnancy  proportions  tnfa  tnfr2  viable 
1b5  allow  antibodies  antigen  antigens  conventionally  cytoplasm  discussed  distributions  dr  embedded  fixed  hla  immunoreactivity  localization  lymphoid  mb1  mb2  membrane  mt1  recognition  recognize  recognized  restricted  sections  significance  tal  ultrastructural  wax 
Tagcloud (Difference) ?
casp3  cl  coincided  corpora  cyclic  disaggregation  estrous  extrinsic  fas  fasl  faslg  fos  ifng  ifngamma  jun  lutea  luteal  luteolysis  luteolytic  p4  pgf2alpha  postmortem  pregnancy  proportions  tnfa  tnfr2  viable 
1b5  allow  antibodies  antigen  antigens  conventionally  cytoplasm  discussed  distributions  dr  embedded  fixed  hla  immunoreactivity  localization  lymphoid  mb1  mb2  membrane  mt1  recognition  recognize  recognized  restricted  sections  significance  tal  ultrastructural  wax 
Tagcloud (Intersection) ?