TNFRSF1A and CASP7

  • Number of citations of the paper that reports this interaction (PMID 11755217)
  • 2
  • Data Source:
  • BioGRID (enzymatic study)
  • HPRD (in vitro)

TNFRSF1A

CASP7

Gene Name tumor necrosis factor receptor superfamily, member 1A caspase 7, apoptosis-related cysteine peptidase
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs) ( 23648065)
  • Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin) ( 23648065)
  • Multiple sclerosis ( 19525953 21833088)
  • Primary biliary cirrhosis ( 21399635)
Protein-Protein Interactions 60 interactors: ADAM17 ATF6 BAG4 BCL10 CASP10 CASP7 CHUK CLIP3 DAPK1 DAXX ERAP1 ERN1 FANCD2 GNB2L1 GRB2 GYS2 HRG HSP90AA1 HSPA8 IKBKB IKBKG JAK1 JAK2 LTA LTB MADD MAGEH1 MAPK1 MOAP1 MYOC NSMAF PIP4K2B PRDX3 PRKCD PSMD2 PTK2 PTPN11 PTPN6 RASSF1 RIPK1 RIPK2 RIPK3 SGTA SRC STAMBP STAT1 SUMO1 SYK TNF TNFRSF25 TNFSF13 TRADD TRAF1 TRAF2 TRAF3 TRAP1 TRPC4AP UBE2I UBQLN1 UCHL1 60 interactors: AR ARHGDIA BIRC2 BIRC3 BIRC5 BIRC6 BIRC7 CASP10 CASP2 CASP3 CASP8 CASP9 CAST CDC42 CFLAR CLSPN COPS6 CTSG DCTN1 DFFA DSP EIF2AK2 GOLGA3 GORASP1 GZMB HSPA5 KRT18 LYN MAPT MAX MEF2A MEF2D NEDD4 PARP1 PLA2G4B PRKCZ PSEN1 PSEN2 PSIP1 PSME3 PTGES3 PTMA RAC1 RAD21 RAD51 RASA1 RB1 RNF7 ROCK1 SAT1 SP1 SPTAN1 SRF STAT1 STK24 TERF1 TNFRSF1A UBE4B VIM XIAP
Entrez ID 7132 840
HPRD ID 01861 03457
Ensembl ID ENSG00000067182 ENSG00000165806
Uniprot IDs J9PH39 P19438 B4DWA2 P55210
PDB IDs 1EXT 1FT4 1ICH 1NCF 1TNR 1F1J 1GQF 1I4O 1I51 1K86 1K88 1KMC 1MIA 1SHJ 1SHL 2QL5 2QL7 2QL9 2QLB 2QLF 2QLJ 3EDR 3H1P 3IBC 3IBF 3R5K 4FDL 4FEA 4HQ0 4HQR 4JB8 4JJ8 4JR1 4JR2
Enriched GO Terms of Interacting Partners?
Tagcloud ?
casp3  cl  coincided  corpora  cyclic  disaggregation  estrous  extrinsic  fas  fasl  faslg  fos  ifng  ifngamma  jun  lutea  luteal  luteolysis  luteolytic  p4  pgf2alpha  postmortem  pregnancy  proportions  tnfa  tnfr2  viable 
balb  casp3  casp8  caspase3  closure  d10  d5  d7  dermal  execution  extrinsic  fasr  harvested  healing  innovation  intersect  intrinsic  mechanistically  mucosal  preprogrammed  punch  scarring  therapeutics  tnfrsf1b  tongue  tradd  trp53  wound  wounds 
Tagcloud (Difference) ?
cl  coincided  corpora  cyclic  disaggregation  estrous  fas  fasl  faslg  fos  ifng  ifngamma  jun  lutea  luteal  luteolysis  luteolytic  p4  pgf2alpha  postmortem  pregnancy  proportions  tnfa  tnfr2  viable 
balb  casp8  caspase3  closure  d10  d5  d7  dermal  execution  fasr  harvested  healing  innovation  intersect  intrinsic  mechanistically  mucosal  preprogrammed  punch  scarring  therapeutics  tongue  tradd  trp53  wound  wounds 
Tagcloud (Intersection) ?
casp3  extrinsic  tnfrsf1b