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CASP10 and OIP5
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
CASP10
OIP5
Gene Name
caspase 10, apoptosis-related cysteine peptidase
Opa interacting protein 5
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Cytosol
Plasma Membrane
CD95 Death-inducing Signaling Complex
Ripoptosome
Chromosome, Centromeric Region
Chromatin
Nucleus
Nucleoplasm
Cytoplasm
Chromocenter
Cajal Body
Molecular Function
Cysteine-type Endopeptidase Activity
Protein Binding
Ubiquitin Protein Ligase Binding
Death Effector Domain Binding
Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway
Protein Binding
Biological Process
Proteolysis
Apoptotic Process
Regulation Of Apoptotic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Innate Immune Response
Apoptotic Signaling Pathway
Nucleosome Assembly
Mitotic Nuclear Division
Cell Communication
CENP-A Containing Nucleosome Assembly
Cell Division
Pathways
RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
TRAIL signaling
Death Receptor Signalling
FasL/ CD95L signaling
Programmed Cell Death
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
Extrinsic Pathway
Innate Immune System
Chromosome Maintenance
Nucleosome assembly
Deposition of new CENPA-containing nucleosomes at the centromere
Drugs
Diseases
GWAS
Protein-Protein Interactions
30 interactors:
BFAR
BID
CASP1
CASP14
CASP2
CASP3
CASP4
CASP6
CASP7
CASP8
CASP8AP2
CASP9
CCAR1
CFLAR
DEDD
DEDD2
DSP
ECE2
FADD
NFKBIL1
OIP5
PHF20L1
POLR2A
PRDX6
RB1
RIOK3
RYBP
TNFRSF1A
TRAF1
XIAP
21 interactors:
ABL2
BRAF
C1orf94
CASP10
CEP170P1
EIF4ENIF1
FOXJ1
GCC1
KDM1A
KRT15
MIS18A
NUP62
PEX19
RAF1
RARG
SKIL
TFIP11
TMPO
TPM3
TRIP6
TSSK3
Entrez ID
843
11339
HPRD ID
03458
09352
Ensembl ID
ENSG00000003400
ENSG00000104147
Uniprot IDs
Q92851
O43482
PDB IDs
Enriched GO Terms of Interacting Partners
?
Apoptotic Process
Programmed Cell Death
Cell Death
Death
Extrinsic Apoptotic Signaling Pathway
Apoptotic Signaling Pathway
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Execution Phase Of Apoptosis
Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Regulation Of Cysteine-type Endopeptidase Activity
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Activation Of Cysteine-type Endopeptidase Activity
Protein Processing
Zymogen Activation
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Cysteine-type Endopeptidase Activity
Positive Regulation Of Endopeptidase Activity
Regulation Of Apoptotic Process
Positive Regulation Of Peptidase Activity
Regulation Of Cell Death
Regulation Of Endopeptidase Activity
Intrinsic Apoptotic Signaling Pathway
Regulation Of Peptidase Activity
Positive Regulation Of Proteolysis
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Cell Death
Regulation Of Proteolysis
Glial Cell Apoptotic Process
Cellular Component Disassembly Involved In Execution Phase Of Apoptosis
Cellular Response To Mechanical Stimulus
Positive Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Protein Metabolic Process
Regulation Of Protein Metabolic Process
Regulation Of Extrinsic Apoptotic Signaling Pathway
Response To Mechanical Stimulus
Positive Regulation Of Macrophage Differentiation
Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Cell Communication
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C
Neuron Apoptotic Process
Intracellular Signal Transduction
Proteolysis
Regulation Of Necroptotic Process
Positive Regulation Of Neuron Apoptotic Process
Neuron Death
Regulation Of Cellular Protein Metabolic Process
Hepatocyte Apoptotic Process
Signaling
Positive Regulation Of Neuron Death
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Intracellular Signal Transduction
Regulation Of Apoptotic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Regulation Of Cell Death
Regulation Of Signal Transduction
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Signal Transduction
Regulation Of Signaling
Negative Regulation Of Apoptotic Process
Negative Regulation Of Programmed Cell Death
Negative Regulation Of Cell Death
Regulation Of Cell Proliferation
Regulation Of Cell Differentiation
Negative Regulation Of Endothelial Cell Apoptotic Process
Negative Regulation Of Cell Differentiation
Negative Regulation Of Signaling
Regulation Of Endothelial Cell Apoptotic Process
Regulation Of Nitrogen Compound Metabolic Process
Cellular Component Assembly
Positive Regulation Of Cell Differentiation
Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Negative Regulation Of Ras Protein Signal Transduction
Positive Regulation Of Lung Ciliated Cell Differentiation
Central Tolerance Induction
Spliceosomal Complex Disassembly
Negative Regulation Of Lipid Binding
Glomerular Parietal Epithelial Cell Development
Regulation Of Primitive Erythrocyte Differentiation
Positive Regulation Of Central B Cell Tolerance Induction
Death-inducing Signaling Complex Assembly
Negative Regulation Of Small GTPase Mediated Signal Transduction
Immune System Process
Regulation Of Metabolic Process
Developmental Process
Regulation Of Binding
Visual Learning
Alpha-beta T Cell Differentiation
Regulation Of MAPK Cascade
Organ Development
Negative Regulation Of Signal Transduction
Activation Of MAPKK Activity
Visual Behavior
Regulation Of Cell Motility
Alpha-beta T Cell Activation
Cellular Response To Retinoic Acid
Somatic Stem Cell Maintenance
Regulation Of Ras Protein Signal Transduction
Positive Regulation Of B Cell Tolerance Induction
Negative Regulation Of Germinal Center Formation
Tagcloud
?
arginine
bcl3
dap1
derepression
epigenetic
epigenetically
governs
hdac1
hodgkin
hoxa5
hrk
indirectly
lymphoma
master
methyltransferase
offer
p52
polycomb
prc2
prmt5
rb1
rbl2
reactivation
repression
repressor
retinoblastoma
tp53k372
trigger
turn
Tagcloud (Difference)
?
arginine
bcl3
dap1
derepression
epigenetic
epigenetically
governs
hdac1
hodgkin
hoxa5
hrk
indirectly
lymphoma
master
methyltransferase
offer
p52
polycomb
prc2
prmt5
rb1
rbl2
reactivation
repression
repressor
retinoblastoma
tp53k372
trigger
turn
Tagcloud (Intersection)
?