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CASP10
Gene Name
caspase 10, apoptosis-related cysteine peptidase
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasm
Cytosol
Plasma Membrane
CD95 Death-inducing Signaling Complex
Ripoptosome
Molecular Function
Cysteine-type Endopeptidase Activity
Protein Binding
Ubiquitin Protein Ligase Binding
Death Effector Domain Binding
Cysteine-type Endopeptidase Activity Involved In Apoptotic Signaling Pathway
Biological Process
Proteolysis
Apoptotic Process
Regulation Of Apoptotic Process
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Innate Immune Response
Apoptotic Signaling Pathway
Pathways
RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
TRAIL signaling
Death Receptor Signalling
FasL/ CD95L signaling
Programmed Cell Death
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
Extrinsic Pathway
Innate Immune System
Drugs
Diseases
GWAS
Protein-protein Interactions
30 interactors:
BFAR
BID
CASP1
CASP14
CASP2
CASP3
CASP4
CASP6
CASP7
CASP8
CASP8AP2
CASP9
CCAR1
CFLAR
DEDD
DEDD2
DSP
ECE2
FADD
NFKBIL1
OIP5
PHF20L1
POLR2A
PRDX6
RB1
RIOK3
RYBP
TNFRSF1A
TRAF1
XIAP
Entrez ID
843
HPRD ID
03458
Ensembl ID
ENSG00000003400
Uniprot IDs
Q92851
PDB IDs
Enriched GO Terms of Interacting Partners
?
Apoptotic Process
Programmed Cell Death
Cell Death
Death
Extrinsic Apoptotic Signaling Pathway
Apoptotic Signaling Pathway
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Execution Phase Of Apoptosis
Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Regulation Of Cysteine-type Endopeptidase Activity
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Activation Of Cysteine-type Endopeptidase Activity
Protein Processing
Zymogen Activation
Positive Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Positive Regulation Of Cysteine-type Endopeptidase Activity
Positive Regulation Of Endopeptidase Activity
Regulation Of Apoptotic Process
Positive Regulation Of Peptidase Activity
Regulation Of Cell Death
Regulation Of Endopeptidase Activity
Intrinsic Apoptotic Signaling Pathway
Regulation Of Peptidase Activity
Positive Regulation Of Proteolysis
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Positive Regulation Of Cell Death
Regulation Of Proteolysis
Glial Cell Apoptotic Process
Cellular Component Disassembly Involved In Execution Phase Of Apoptosis
Cellular Response To Mechanical Stimulus
Positive Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Protein Metabolic Process
Regulation Of Protein Metabolic Process
Regulation Of Extrinsic Apoptotic Signaling Pathway
Response To Mechanical Stimulus
Positive Regulation Of Macrophage Differentiation
Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand
Cell Communication
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process By Cytochrome C
Neuron Apoptotic Process
Intracellular Signal Transduction
Proteolysis
Regulation Of Necroptotic Process
Positive Regulation Of Neuron Apoptotic Process
Neuron Death
Regulation Of Cellular Protein Metabolic Process
Hepatocyte Apoptotic Process
Signaling
Positive Regulation Of Neuron Death
Tagcloud
?
arginine
bcl3
dap1
derepression
epigenetic
epigenetically
governs
hdac1
hodgkin
hoxa5
hrk
indirectly
lymphoma
master
methyltransferase
offer
p52
polycomb
prc2
prmt5
rb1
rbl2
reactivation
repression
repressor
retinoblastoma
tp53k372
trigger
turn