TNFRSF1A and STAT1

  • Number of citations of the paper that reports this interaction (PMID 10848577)
  • 28
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vitro)

TNFRSF1A

STAT1

Gene Name tumor necrosis factor receptor superfamily, member 1A signal transducer and activator of transcription 1, 91kDa
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs) ( 23648065)
  • Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin) ( 23648065)
  • Multiple sclerosis ( 19525953 21833088)
  • Primary biliary cirrhosis ( 21399635)
  • Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions 60 interactors: ADAM17 ATF6 BAG4 BCL10 CASP10 CASP7 CHUK CLIP3 DAPK1 DAXX ERAP1 ERN1 FANCD2 GNB2L1 GRB2 GYS2 HRG HSP90AA1 HSPA8 IKBKB IKBKG JAK1 JAK2 LTA LTB MADD MAGEH1 MAPK1 MOAP1 MYOC NSMAF PIP4K2B PRDX3 PRKCD PSMD2 PTK2 PTPN11 PTPN6 RASSF1 RIPK1 RIPK2 RIPK3 SGTA SRC STAMBP STAT1 SUMO1 SYK TNF TNFRSF25 TNFSF13 TRADD TRAF1 TRAF2 TRAF3 TRAP1 TRPC4AP UBE2I UBQLN1 UCHL1 103 interactors: ACTN4 ADRA1B AKT1 ATF3 BMX BRCA1 CAMK2D CAMK2G CASP3 CASP7 CCR1 CCR5 CREBBP CSE1L CSF2RB CXCR4 DCTN1 DDB1 DOT1L DUSP3 E2F1 EGFR EIF1AD EIF2AK2 ELP2 EP300 ERBB2 FADD FANCC FGFR3 FGFR4 FLT1 FOS FYN GFAP GNB2L1 GTF2I HADH HLA-B HSF1 HSP90AB1 IFNAR2 IFNGR1 IL27RA IL2RB IL2RG IRF1 IRF2 IRF9 JAK1 JAK2 JUN KDR KIT KPNA1 KPNA6 LCK LMO2 LZTR1 MAPK14 MAVS MCM3 MCM5 MDK ND4L NMI NOMO1 NOMO2 OTUD4 PDGFRA PDGFRB PIAS1 PIK3CA POR PRKCD PRMT1 PRMT3 PTK2 PTPN11 PTPN2 RAC1 RELA RPS6KA5 RXRA SHANK1 SPTAN1 SPTBN1 SRC STAT2 STAT3 STAT5A STAT5B SUMO4 SYK TNFRSF1A TNFRSF1B TRADD TYK2 UBC UBE2I VDR XPO1 ZNF467
Entrez ID 7132 6772
HPRD ID 01861 02777
Ensembl ID ENSG00000067182 ENSG00000115415
Uniprot IDs J9PH39 P19438 J3KPM9 P42224
PDB IDs 1EXT 1FT4 1ICH 1NCF 1TNR 1BF5 1YVL 2KA6
Enriched GO Terms of Interacting Partners?
Tagcloud ?
casp3  cl  coincided  corpora  cyclic  disaggregation  estrous  extrinsic  fas  fasl  faslg  fos  ifng  ifngamma  jun  lutea  luteal  luteolysis  luteolytic  p4  pgf2alpha  postmortem  pregnancy  proportions  tnfa  tnfr2  viable 
augment  augments  bait  cbp  coactivator  coil  coiled  enhances  except  hybrid  ifngamma  instead  interactor  interacts  interestingly  intrinsic  lacks  myc  nmi  potentiate  recruitment  reveal  screen  stat2  stat5  stat5b  stats  yeast 
Tagcloud (Difference) ?
casp3  cl  coincided  corpora  cyclic  disaggregation  estrous  extrinsic  fas  fasl  faslg  fos  ifng  jun  lutea  luteal  luteolysis  luteolytic  p4  pgf2alpha  postmortem  pregnancy  proportions  tnfa  tnfr2  viable 
augment  augments  bait  cbp  coactivator  coil  coiled  enhances  except  hybrid  instead  interactor  interacts  interestingly  intrinsic  lacks  myc  nmi  potentiate  recruitment  reveal  screen  stat2  stat5  stat5b  stats  yeast 
Tagcloud (Intersection) ?
ifngamma