TNFRSF1A and MADD

  • Number of citations of the paper that reports this interaction (PMID 9115275)
  • 23
  • Data Source:
  • HPRD (in vitro)

TNFRSF1A

MADD

Gene Name tumor necrosis factor receptor superfamily, member 1A MAP-kinase activating death domain
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Adverse response to chemotherapy (neutropenia/leucopenia) (all anthracycline-based drugs) ( 23648065)
  • Adverse response to chemotherapy (neutropenia/leucopenia) (epirubicin) ( 23648065)
  • Multiple sclerosis ( 19525953 21833088)
  • Primary biliary cirrhosis ( 21399635)
  • Fasting glucose-related traits ( 20081858)
  • Fasting glucose-related traits (interaction with BMI) ( 22581228)
  • HDL cholesterol ( 19060911)
  • Proinsulin levels ( 21873549)
Protein-Protein Interactions 60 interactors: ADAM17 ATF6 BAG4 BCL10 CASP10 CASP7 CHUK CLIP3 DAPK1 DAXX ERAP1 ERN1 FANCD2 GNB2L1 GRB2 GYS2 HRG HSP90AA1 HSPA8 IKBKB IKBKG JAK1 JAK2 LTA LTB MADD MAGEH1 MAPK1 MOAP1 MYOC NSMAF PIP4K2B PRDX3 PRKCD PSMD2 PTK2 PTPN11 PTPN6 RASSF1 RIPK1 RIPK2 RIPK3 SGTA SRC STAMBP STAT1 SUMO1 SYK TNF TNFRSF25 TNFSF13 TRADD TRAF1 TRAF2 TRAF3 TRAP1 TRPC4AP UBE2I UBQLN1 UCHL1 9 interactors: NPDC1 PIDD1 POT1 PTPRN TNFRSF10A TNFRSF10B TNFRSF1A VPS13D YWHAZ
Entrez ID 7132 8567
HPRD ID 01861 04664
Ensembl ID ENSG00000067182 ENSG00000110514
Uniprot IDs J9PH39 P19438 Q8WXG6
PDB IDs 1EXT 1FT4 1ICH 1NCF 1TNR
Enriched GO Terms of Interacting Partners?
Tagcloud ?
casp3  cl  coincided  corpora  cyclic  disaggregation  estrous  extrinsic  fas  fasl  faslg  fos  ifng  ifngamma  jun  lutea  luteal  luteolysis  luteolytic  p4  pgf2alpha  postmortem  pregnancy  proportions  tnfa  tnfr2  viable 
abca1  abcg5  abcg8  atorvastatin  causal  challenging  chow  excised  fads1  gwas  hfd  hypertensive  list  loci  lpl  nominally  nr1h3  orthologs  overlapped  pcsk9  pltp  qpcr  qtl  responded  spontaneously  stac3  staged  suggestive  timd4 
Tagcloud (Difference) ?
casp3  cl  coincided  corpora  cyclic  disaggregation  estrous  extrinsic  fas  fasl  faslg  fos  ifng  ifngamma  jun  lutea  luteal  luteolysis  luteolytic  p4  pgf2alpha  postmortem  pregnancy  proportions  tnfa  tnfr2  viable 
abca1  abcg5  abcg8  atorvastatin  causal  challenging  chow  excised  fads1  gwas  hfd  hypertensive  list  loci  lpl  nominally  nr1h3  orthologs  overlapped  pcsk9  pltp  qpcr  qtl  responded  spontaneously  stac3  staged  suggestive  timd4 
Tagcloud (Intersection) ?