CTNNBL1 and CDCA7L

Number of citations of the paper that reports this interaction (PubMedID 29892012)
71

Data Source:
BioGRID (two hybrid, two hybrid)

		CTNNBL1	CDCA7L
Description		catenin beta like 1	cell division cycle associated 7 like
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GO Annotations	Cellular Component	Prp19 Complex Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Centrosome Cytosol Membrane	Fibrillar Center Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol
	Molecular Function	Protein Binding Enzyme Binding	Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Adaptive Immune Response Immune System Process MRNA Processing RNA Splicing Gene Expression Somatic Diversification Of Immunoglobulins Positive Regulation Of Apoptotic Process	Regulation Of DNA-templated Transcription Positive Regulation Of Cell Population Proliferation
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Bone mineral density ( 17903296) California verbal learning test score ( 31596458) Falling risk ( 32999390) Fasting glucose ( 34074324)	Breast cancer ( 29059683) Gamma glutamyl transferase levels ( 33339817) Height ( 20189936) Multiple myeloma ( 26007630 33875642) Multiple myeloma and monoclonal gammopathy ( 26007630) Pre-treatment viral load in HIV-1 infection ( 31219150) Squamous cell lung carcinoma ( 28604730) Urate levels in obese individuals ( 25811787)
Interacting Genes		26 interacting genes: BEX3 BUD31 CALCOCO1 CATIP CDCA7L CREBZF ERP29 HMGB1 HNRNPK IK LDOC1 LUC7L MAPK8IP2 MED4 MEOX2 NSRP1 PPP1R8 PRDM4 PRPF3 SPP1 SRPK2 STAMBP SUMO2 U2SURP WBP11 ZCCHC10	68 interacting genes: ABT1 ANKRD1 ANKRD11 ANKRD23 AVPI1 AXIN1 BAG5 BEND7 BRPF1 BYSL CARD9 CAVIN1 CCDC116 CCDC33 CEP70 CTNNBL1 DAXX DEDD2 DMAP1 EIF4A3 FAM217B FAM9B GOLGA2 GPRASP3 HSF2BP ING5 JADE2 KRTAP10-7 LMO1 MCRS1 MDFI MEOX2 MFAP1 MLH1 MORN3 MRPL28 MYC NDUFB7 NOL12 NOP2 PBX1 PBX2 PICK1 PIH1D1 PIP4K2B PPP1R16A PPP1R16B PRDM14 PRPF31 RRP7A SNRNP48 SSX1 SSX2IP STX11 SUV39H1 TADA2A TFPT TNNI1 TRAF3IP3 TRIM42 UBL4A UTP3 VDR ZGPAT ZNF250 ZNF438 ZNF620 ZNF821
Entrez ID		56259	55536
HPRD ID		10850	11481
Ensembl ID		ENSG00000132792	ENSG00000164649
Uniprot IDs		Q8WYA6	A8K8X5 Q96GN5
PDB IDs		4CB8 4CB9 4CBA 4HM9 4HNM 4MFU 4MFV 7ABI	5YI9 6EMO
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing RNA Metabolic Process RNA Processing MRNA Metabolic Process Spliceosomal Complex Nucleus Positive Regulation Of Macromolecule Biosynthetic Process Nuclear Speck Nucleoplasm Positive Regulation Of Biosynthetic Process Positive Regulation Of RNA Biosynthetic Process Nucleic Acid Metabolic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Positive Regulation Of RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Binding Positive Regulation Of Macromolecule Metabolic Process Macrophage Activation Involved In Immune Response Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Nucleobase-containing Compound Metabolic Process MRNA Binding Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Transcription Coactivator Activity Regulation Of Toll-like Receptor 4 Signaling Pathway Calcium-dependent Protein Kinase Regulator Activity Regulation Of Restriction Endodeoxyribonuclease Activity Lipopolysaccharide Binding Protein Binding Positive Regulation Of Myeloid Progenitor Cell Differentiation Regulation Of Cellular Response To Stress Regulation Of MRNA Processing Ribonuclease E Activity Molecular Function Inhibitor Activity Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Regulation Of Gene Expression	Nucleus RRNA Metabolic Process Nucleoplasm Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Protein Binding RRNA Processing Regulation Of RNA Metabolic Process Histone Acetyltransferase Complex Regulation Of Nucleobase-containing Compound Metabolic Process Chromatin Organization RNA Metabolic Process Chromatin Remodeling Chromosome Nucleolus Nucleic Acid Metabolic Process RNA Processing Regulation Of Transcription By RNA Polymerase II Regulation Of Macromolecule Biosynthetic Process Regulation Of DNA Metabolic Process Regulation Of Primary Metabolic Process SnoRNA Localization Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Myosin Phosphatase Regulator Activity Negative Regulation Of Nucleobase-containing Compound Metabolic Process Apoptotic Signaling Pathway MOZ/MORF Histone Acetyltransferase Complex Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Protein Localization To Nucleolus Spliceosomal Complex Histone H4K5 Acetyltransferase Activity Histone H4K8 Acetyltransferase Activity Histone H4K12 Acetyltransferase Activity Negative Regulation Of RNA Metabolic Process Skeletal System Morphogenesis DNA Binding Positive Regulation Of Biosynthetic Process Protein-RNA Complex Assembly Titin Binding Regulation Of DNA Replication Dorsal/ventral Axis Specification Regulation Of Signal Transduction By P53 Class Mediator Epigenetic Programming In The Zygotic Pronuclei Positive Regulation Of Telomere Maintenance In Response To DNA Damage
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