CTNNBL1 and CALCOCO1

Number of citations of the paper that reports this interaction (PubMedID 16344550)
52

Data Source:
HPRD (in vitro, in vivo)

		CTNNBL1	CALCOCO1
Description		catenin beta like 1	calcium binding and coiled-coil domain 1
Image			No pdb structure
GO Annotations	Cellular Component	Prp19 Complex Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Centrosome Cytosol Membrane	Chromatin Nucleus Cytoplasm Cytosol
	Molecular Function	Protein Binding Enzyme Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Chromatin Binding Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Beta-catenin Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	MRNA Splicing, Via Spliceosome Adaptive Immune Response Immune System Process MRNA Processing RNA Splicing Gene Expression Somatic Diversification Of Immunoglobulins Positive Regulation Of Apoptotic Process	Signal Transduction Positive Regulation Of Gene Expression Wnt Signaling Pathway Nuclear Receptor-mediated Steroid Hormone Signaling Pathway Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II
Pathways		mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Bone mineral density ( 17903296) California verbal learning test score ( 31596458) Falling risk ( 32999390) Fasting glucose ( 34074324)	Panic disorder ( 19165232) Toenail selenium levels ( 25343990) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		26 interacting genes: BEX3 BUD31 CALCOCO1 CATIP CDCA7L CREBZF ERP29 HMGB1 HNRNPK IK LDOC1 LUC7L MAPK8IP2 MED4 MEOX2 NSRP1 PPP1R8 PRDM4 PRPF3 SPP1 SRPK2 STAMBP SUMO2 U2SURP WBP11 ZCCHC10	37 interacting genes: APP APTX ARNT BFSP2 CEP19 CREBBP CRYBA2 CTNNBL1 CWF19L2 CYTH3 DUSP13B ENKD1 EP300 FAM161A FOSL1 FXR1 GABARAPL1 GABARAPL2 GRIK2 IPP ISOC1 KRT15 MAPK1 MYH6 NDC80 NEDD4 PCBD1 POLR2A PRKAA2 RNF8 SH3GL3 SHANK3 SMURF1 SRPK2 TBC1D15 TBC1D17 ZMAT2
Entrez ID		56259	57658
HPRD ID		10850	13868
Ensembl ID		ENSG00000132792	ENSG00000012822
Uniprot IDs		Q8WYA6	Q9P1Z2
PDB IDs		4CB8 4CB9 4CBA 4HM9 4HNM 4MFU 4MFV 7ABI
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing RNA Metabolic Process RNA Processing MRNA Metabolic Process Spliceosomal Complex Nucleus Positive Regulation Of Macromolecule Biosynthetic Process Nuclear Speck Nucleoplasm Positive Regulation Of Biosynthetic Process Positive Regulation Of RNA Biosynthetic Process Nucleic Acid Metabolic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Positive Regulation Of RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Binding Positive Regulation Of Macromolecule Metabolic Process Macrophage Activation Involved In Immune Response Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Nucleobase-containing Compound Metabolic Process MRNA Binding Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Transcription Coactivator Activity Regulation Of Toll-like Receptor 4 Signaling Pathway Calcium-dependent Protein Kinase Regulator Activity Regulation Of Restriction Endodeoxyribonuclease Activity Lipopolysaccharide Binding Protein Binding Positive Regulation Of Myeloid Progenitor Cell Differentiation Regulation Of Cellular Response To Stress Regulation Of MRNA Processing Ribonuclease E Activity Molecular Function Inhibitor Activity Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Regulation Of Gene Expression	Cytoplasm Regulation Of Long-term Neuronal Synaptic Plasticity Organelle Assembly Regulation Of Glycolytic Process Histone H3K27 Acetyltransferase Activity Regulation Of Neuronal Synaptic Plasticity Regulation Of Carbohydrate Catabolic Process Positive Regulation Of Glycolytic Process Histone H3K18 Acetyltransferase Activity N-terminal Peptidyl-lysine Acetylation Peptide Lactyltransferase (CoA-dependent) Activity Cellular Response To Nutrient Levels Regulation Of ATP Metabolic Process Regulation Of Purine Nucleotide Metabolic Process Nucleoplasm Intracellular Signal Transduction Ciliary Basal Body Positive Regulation Of ATP Metabolic Process Regulation Of Synaptic Plasticity Regulation Of Tubulin Deacetylation Regulation Of Long-term Synaptic Potentiation Modulation Of Excitatory Postsynaptic Potential Positive Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Generation Of Precursor Metabolites And Energy Cellular Response To Nitrogen Starvation Regulation Of Protein Deacetylation Positive Regulation Of Synaptic Transmission Negative Regulation Of Long-term Synaptic Potentiation N-terminal Protein Amino Acid Acetylation Cellular Response To Stress Peptidyl-lysine Acetylation Intracellular Signaling Cassette Positive Regulation Of Small Molecule Metabolic Process Cytosol Damaged DNA Binding Prp19 Complex Phosphatidylethanolamine Binding Regulation Of Plasma Membrane Bounded Cell Projection Organization Positive Regulation Of Neuron Apoptotic Process Regulation Of Cellular Response To Heat Ubiquitin Protein Ligase Binding Regulation Of Cell Projection Organization Chromatin Binding Organelle Organization Scaffold Protein Binding Regulation Of Synaptic Transmission, Glutamatergic Response To Nutrient Levels GABA Receptor Binding Regulation Of Small Molecule Metabolic Process Cellular Response To Starvation
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