CTNNBL1 and PPP1R8

Number of citations of the paper that reports this interaction (PubMedID 22365833)
0

Data Source:
BioGRID (two hybrid, two hybrid)

		CTNNBL1	PPP1R8
Description		catenin beta like 1	protein phosphatase 1 regulatory subunit 8
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GO Annotations	Cellular Component	Prp19 Complex Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Centrosome Cytosol Membrane	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Nuclear Speck
	Molecular Function	Protein Binding Enzyme Binding	DNA Binding RNA Binding MRNA Binding Nuclease Activity Endonuclease Activity RNA Endonuclease Activity Protein Phosphatase Inhibitor Activity Protein Serine/threonine Phosphatase Inhibitor Activity Protein Binding Ribonuclease E Activity Hydrolase Activity Protein Phosphatase Regulator Activity Molecular Function Inhibitor Activity
	Biological Process	MRNA Splicing, Via Spliceosome Adaptive Immune Response Immune System Process MRNA Processing RNA Splicing Gene Expression Somatic Diversification Of Immunoglobulins Positive Regulation Of Apoptotic Process	MRNA Processing RNA Catabolic Process Cell Population Proliferation RNA Splicing
Pathways		mRNA Splicing - Major Pathway	mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS		Body size at age 10 ( 32376654) Bone mineral density ( 17903296) California verbal learning test score ( 31596458) Falling risk ( 32999390) Fasting glucose ( 34074324)
Interacting Genes		26 interacting genes: BEX3 BUD31 CALCOCO1 CATIP CDCA7L CREBZF ERP29 HMGB1 HNRNPK IK LDOC1 LUC7L MAPK8IP2 MED4 MEOX2 NSRP1 PPP1R8 PRDM4 PRPF3 SPP1 SRPK2 STAMBP SUMO2 U2SURP WBP11 ZCCHC10	28 interacting genes: APP APPBP2 CDC5L CNKSR1 CREBBP CRMP1 CSNK2A1 CSNK2A2 CTNNBL1 EED ERG28 FBXO25 GBP2 HDAC2 HMGA1 LRRK2 LYN MELK PPIL1 PPP1CA PPP1CC PRKACA RBM48 RTN4IP1 SETDB1 SF3B1 STC2 WDR77
Entrez ID		56259	5511
HPRD ID		10850	04028
Ensembl ID		ENSG00000132792	ENSG00000117751
Uniprot IDs		Q8WYA6	Q12972 Q6ICT4
PDB IDs		4CB8 4CB9 4CBA 4HM9 4HNM 4MFU 4MFV 7ABI	3V4Y
Enriched GO Terms of Interacting Partners?		RNA Splicing MRNA Processing RNA Metabolic Process RNA Processing MRNA Metabolic Process Spliceosomal Complex Nucleus Positive Regulation Of Macromolecule Biosynthetic Process Nuclear Speck Nucleoplasm Positive Regulation Of Biosynthetic Process Positive Regulation Of RNA Biosynthetic Process Nucleic Acid Metabolic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Positive Regulation Of RNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Binding Positive Regulation Of Macromolecule Metabolic Process Macrophage Activation Involved In Immune Response Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Nucleobase-containing Compound Metabolic Process MRNA Binding Regulation Of MRNA Splicing, Via Spliceosome Positive Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of RNA Metabolic Process Transcription Coactivator Activity Regulation Of Toll-like Receptor 4 Signaling Pathway Calcium-dependent Protein Kinase Regulator Activity Regulation Of Restriction Endodeoxyribonuclease Activity Lipopolysaccharide Binding Protein Binding Positive Regulation Of Myeloid Progenitor Cell Differentiation Regulation Of Cellular Response To Stress Regulation Of MRNA Processing Ribonuclease E Activity Molecular Function Inhibitor Activity Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Regulation Of Gene Expression	Macromolecule Metabolic Process Nucleoplasm Postsynapse Cellular Response To Catecholamine Stimulus Response To Catecholamine Protein Modification Process Protein Kinase CK2 Complex Intracellular Signal Transduction Protein Metabolic Process Spliceosomal Complex Cellular Response To Stress Regulation Of Proteolysis Enzyme Binding MRNA Metabolic Process Rhythmic Process Cellular Response To Dopamine PTW/PP1 Phosphatase Complex Chromatin Remodeling Negative Regulation Of Macromolecule Metabolic Process Signaling Receptor Activator Activity Nucleobase-containing Compound Metabolic Process MRNA Processing Response To Dopamine Cellular Response To Heat Perikaryon Cellular Response To Manganese Ion Chromatin Binding Protein Kinase Activity DNA Repair Positive Regulation Of Gliogenesis Regulation Of Carbohydrate Catabolic Process Negative Regulation Of Metabolic Process Nucleic Acid Metabolic Process Circadian Regulation Of Gene Expression DNA Damage Response Positive Regulation Of Programmed Cell Death Nucleus Response To Manganese Ion Prp19 Complex Protein Serine Kinase Activity Golgi-associated Vesicle Chromatin Organization Regulation Of Apoptotic Process Regulation Of Protein Catabolic Process RNA Splicing MRNA Splicing, Via Spliceosome Regulation Of Proteasomal Protein Catabolic Process Regulation Of Macroautophagy ESC/E(Z) Complex Negative Regulation Of Gene Expression
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