EZH2 and DNMT1

  • Number of citations of the paper that reports this interaction (PMID 16357870)
  • 388
  • Data Source:
  • BioGRID (affinity chromatography technology, affinity chromatography technology)
  • HPRD (in vitro)

EZH2

DNMT1

Gene Name enhancer of zeste 2 polycomb repressive complex 2 subunit DNA (cytosine-5-)-methyltransferase 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 64 interactors: AKT1 ATP1A1 ATP1B1 ATRX BRCA1 C7orf25 CCDC85B CDK1 CDK2 CDK6 CDKN2B-AS1 CEP63 DNAJB11 DNMT1 DNMT3A DNMT3B E2F6 EED EHMT1 EPC2 GADD45G GTF3C1 HDAC1 HIST1H1A HIST1H3A HIST3H3 HOTAIR JAK2 KDM1A KLHDC2 MAP3K7 MAPK8IP2 MAPKAPK3 MED1 NINL PFDN1 PHB2 PHF1 PIN4 PJA1 POLA2 PRMT5 PSMB6 RASA1 RBBP4 RBL2 RELA RELB RPN2 RPS6KA5 SMN1 SMS SMYD3 SUV39H1 SUZ12 TAF1D TK1 TNFSF11 USP7 VAV1 WDR61 WSB2 ZAK ZMYND11 31 interactors: AKT1 BAZ2A CBX1 CSNK2B DAXX DMAP1 DNMT3A DNMT3B DYNLL1 EED EZH2 GSK3B HDAC1 HDAC2 HELLS HMGB1 MECP2 NRIP1 PCNA RB1 RGS6 RPS6KA6 RUNX1 RUNX1T1 SETD7 SUV39H1 TRIM27 TSG101 UHRF1 USP7 YWHAQ
Entrez ID 2146 1786
HPRD ID 03342 00532
Ensembl ID ENSG00000106462 ENSG00000130816
Uniprot IDs Q15910 S4S3R8 I6L9H2 P26358
PDB IDs 2C6V 4MI0 3EPZ 3PTA 3SWR
Enriched GO Terms of Interacting Partners?
Tagcloud ?
70z  bait  cdnas  coexpressed  coimmunoprecipitated  compositions  confirming  developmentally  drosophila  ectoderm  eed  esc  fragment  gal4  homolog  hybrid  hypomorphic  lethal  mammalian  polycomb  repeats  represses  repressor  silenced  t1031a  t1040c  wd40  yeast  zeste 
cpg  cues  de  dense  dnmt3a  dnmt3b  dnmts  enhancers  ensure  ensures  establishment  excluded  guide  lethal  localize  methylated  methylation  methylome  methyltransferase  methyltransferases  novo  nucleosomes  observe  preferential  promoters  pwwp  reflects  setd2  transcribed 
Tagcloud (Difference) ?
70z  bait  cdnas  coexpressed  coimmunoprecipitated  compositions  confirming  developmentally  drosophila  ectoderm  eed  esc  fragment  gal4  homolog  hybrid  hypomorphic  mammalian  polycomb  repeats  represses  repressor  silenced  t1031a  t1040c  wd40  yeast  zeste 
cpg  cues  de  dense  dnmt3a  dnmt3b  dnmts  enhancers  ensure  ensures  establishment  excluded  guide  localize  methylated  methylation  methylome  methyltransferase  methyltransferases  novo  nucleosomes  observe  preferential  promoters  pwwp  reflects  setd2  transcribed 
Tagcloud (Intersection) ?
lethal