EZH2 and SUZ12

  • Number of citations of the paper that reports this interaction (PMID 20075857)
  • 133
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo)

EZH2

SUZ12

Gene Name enhancer of zeste 2 polycomb repressive complex 2 subunit SUZ12 polycomb repressive complex 2 subunit
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 64 interactors: AKT1 ATP1A1 ATP1B1 ATRX BRCA1 C7orf25 CCDC85B CDK1 CDK2 CDK6 CDKN2B-AS1 CEP63 DNAJB11 DNMT1 DNMT3A DNMT3B E2F6 EED EHMT1 EPC2 GADD45G GTF3C1 HDAC1 HIST1H1A HIST1H3A HIST3H3 HOTAIR JAK2 KDM1A KLHDC2 MAP3K7 MAPK8IP2 MAPKAPK3 MED1 NINL PFDN1 PHB2 PHF1 PIN4 PJA1 POLA2 PRMT5 PSMB6 RASA1 RBBP4 RBL2 RELA RELB RPN2 RPS6KA5 SMN1 SMS SMYD3 SUV39H1 SUZ12 TAF1D TK1 TNFSF11 USP7 VAV1 WDR61 WSB2 ZAK ZMYND11 15 interactors: AEBP2 CDK19 CDK8 CREB1 CTCF EZH2 HIST1H1A HIST3H3 MED17 MED6 PAXIP1 PJA1 UBE2I USP7 WDR77
Entrez ID 2146 23512
HPRD ID 03342 06949
Ensembl ID ENSG00000106462 ENSG00000178691
Uniprot IDs Q15910 S4S3R8 A8K1U9 J3QQW9 Q15022
PDB IDs 2C6V 4MI0
Enriched GO Terms of Interacting Partners?
Tagcloud ?
70z  bait  cdnas  coexpressed  coimmunoprecipitated  compositions  confirming  developmentally  drosophila  ectoderm  eed  esc  fragment  gal4  homolog  hybrid  hypomorphic  lethal  mammalian  polycomb  repeats  represses  repressor  silenced  t1031a  t1040c  wd40  yeast  zeste 
arise  border  cartilage  cooperates  craniofacial  crest  differentiate  ectoderm  eed  embryogenesis  expand  extensively  ezh2  fails  h3k27  learnt  migrate  neural  occupancy  plate  polycomb  prc2  repressive  slug  snail2  specification  trimethylation  vertebrate  xenopus 
Tagcloud (Difference) ?
70z  bait  cdnas  coexpressed  coimmunoprecipitated  compositions  confirming  developmentally  drosophila  esc  fragment  gal4  homolog  hybrid  hypomorphic  lethal  mammalian  repeats  represses  repressor  silenced  t1031a  t1040c  wd40  yeast  zeste 
arise  border  cartilage  cooperates  craniofacial  crest  differentiate  embryogenesis  expand  extensively  fails  h3k27  learnt  migrate  neural  occupancy  plate  prc2  repressive  slug  snail2  specification  trimethylation  vertebrate  xenopus 
Tagcloud (Intersection) ?
ectoderm  eed  ezh2  polycomb