EZH2 and VAV1

  • Number of citations of the paper that reports this interaction (PMID 15882624)
  • 63
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (two hybrid, in vivo, in vitro)

EZH2

VAV1

Gene Name enhancer of zeste 2 polycomb repressive complex 2 subunit vav 1 guanine nucleotide exchange factor
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 64 interactors: AKT1 ATP1A1 ATP1B1 ATRX BRCA1 C7orf25 CCDC85B CDK1 CDK2 CDK6 CDKN2B-AS1 CEP63 DNAJB11 DNMT1 DNMT3A DNMT3B E2F6 EED EHMT1 EPC2 GADD45G GTF3C1 HDAC1 HIST1H1A HIST1H3A HIST3H3 HOTAIR JAK2 KDM1A KLHDC2 MAP3K7 MAPK8IP2 MAPKAPK3 MED1 NINL PFDN1 PHB2 PHF1 PIN4 PJA1 POLA2 PRMT5 PSMB6 RASA1 RBBP4 RBL2 RELA RELB RPN2 RPS6KA5 SMN1 SMS SMYD3 SUV39H1 SUZ12 TAF1D TK1 TNFSF11 USP7 VAV1 WDR61 WSB2 ZAK ZMYND11 77 interactors: ABL1 ACTA1 AOC3 ARHGDIA ARHGDIB BCR BLNK BTK CASP3 CBL CBLB CD19 CDC42 CRK CXCR4 DNM2 DOCK2 DOK1 EGFR EMD EPOR ERBB2 ERBB3 EZH2 FGFR1 FYN GRB2 HCK HNRNPK HRAS IL6ST INSR JAK2 JUN KHDRBS1 LAT LCK LCP2 LMNA MAPK1 MERTK MET NEK3 PAG1 PDGFRB PHAX PIK3R1 PLCG1 PRKCQ PRLR PTK2B PTPN22 PTPN6 RAC1 RACGAP1 RAF1 RHOA RHOG S100B SH3BP2 SHB SHC1 SIAH1 SIAH2 SLA SOCS1 SYK TEC TUBA1A TUBA4A TUBB TYK2 XRCC5 XRCC6 ZAP70 ZNF655 ZYX
Entrez ID 2146 7409
HPRD ID 03342 01284
Ensembl ID ENSG00000106462 ENSG00000141968
Uniprot IDs Q15910 S4S3R8 B2R8B5 P15498 Q96D37
PDB IDs 2C6V 4MI0 2CRH 2LCT 2MC1 2ROR 3BJI 3KY9
Enriched GO Terms of Interacting Partners?
Tagcloud ?
70z  bait  cdnas  coexpressed  coimmunoprecipitated  compositions  confirming  developmentally  drosophila  ectoderm  eed  esc  fragment  gal4  homolog  hybrid  hypomorphic  lethal  mammalian  polycomb  repeats  represses  repressor  silenced  t1031a  t1040c  wd40  yeast  zeste 
abilities  abnormally  blocking  colony  csf1  cytoskeleton  effector  erk  exclusively  fibrosis  h358  hematopoietic  herein  infiltrating  lung  microenvironment  organization  scaffold  scid  secrete  secretome  silenced  smaller  stimulating  supported  supporting  talk  transcriptome  transducer 
Tagcloud (Difference) ?
70z  bait  cdnas  coexpressed  coimmunoprecipitated  compositions  confirming  developmentally  drosophila  ectoderm  eed  esc  fragment  gal4  homolog  hybrid  hypomorphic  lethal  mammalian  polycomb  repeats  represses  repressor  t1031a  t1040c  wd40  yeast  zeste 
abilities  abnormally  blocking  colony  csf1  cytoskeleton  effector  erk  exclusively  fibrosis  h358  hematopoietic  herein  infiltrating  lung  microenvironment  organization  scaffold  scid  secrete  secretome  smaller  stimulating  supported  supporting  talk  transcriptome  transducer 
Tagcloud (Intersection) ?
silenced