EZH2 and DNMT3B

  • Number of citations of the paper that reports this interaction (PMID 16357870)
  • 388
  • Data Source:
  • BioGRID (affinity chromatography technology, affinity chromatography technology)
  • HPRD (in vitro)

EZH2

DNMT3B

Gene Name enhancer of zeste 2 polycomb repressive complex 2 subunit DNA (cytosine-5-)-methyltransferase 3 beta
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions 64 interactors: AKT1 ATP1A1 ATP1B1 ATRX BRCA1 C7orf25 CCDC85B CDK1 CDK2 CDK6 CDKN2B-AS1 CEP63 DNAJB11 DNMT1 DNMT3A DNMT3B E2F6 EED EHMT1 EPC2 GADD45G GTF3C1 HDAC1 HIST1H1A HIST1H3A HIST3H3 HOTAIR JAK2 KDM1A KLHDC2 MAP3K7 MAPK8IP2 MAPKAPK3 MED1 NINL PFDN1 PHB2 PHF1 PIN4 PJA1 POLA2 PRMT5 PSMB6 RASA1 RBBP4 RBL2 RELA RELB RPN2 RPS6KA5 SMN1 SMS SMYD3 SUV39H1 SUZ12 TAF1D TK1 TNFSF11 USP7 VAV1 WDR61 WSB2 ZAK ZMYND11 35 interactors: BAZ2A CBX1 CBX3 CBX5 CMTM6 DNMT1 DNMT3A DNMT3L DUSP23 EED EZH2 HDAC1 HDAC2 HELLS KIF4A MAP1LC3B MBD4 NCAPG NEDD8 NRIP1 PAM16 PCYT2 PLEKHJ1 RPS10 SMARCA5 SMC2 SPI1 SUMO1 SUV39H1 TDG TSC22D1 UBE2I UBE2W WARS ZBTB18
Entrez ID 2146 1789
HPRD ID 03342 04209
Ensembl ID ENSG00000106462 ENSG00000088305
Uniprot IDs Q15910 S4S3R8 Q9UBC3
PDB IDs 2C6V 4MI0 3FLG 3QKJ
Enriched GO Terms of Interacting Partners?
Tagcloud ?
70z  bait  cdnas  coexpressed  coimmunoprecipitated  compositions  confirming  developmentally  drosophila  ectoderm  eed  esc  fragment  gal4  homolog  hybrid  hypomorphic  lethal  mammalian  polycomb  repeats  represses  repressor  silenced  t1031a  t1040c  wd40  yeast  zeste 
cpg  cues  de  dense  dnmt1  dnmts  enhancers  ensure  ensures  establishment  excluded  guide  lethal  localize  methylated  methylation  methylome  methyltransferase  methyltransferases  novo  nucleosomes  observe  preferential  promoters  pwwp  reflects  setd2  transcribed 
Tagcloud (Difference) ?
70z  bait  cdnas  coexpressed  coimmunoprecipitated  compositions  confirming  developmentally  drosophila  ectoderm  eed  esc  fragment  gal4  homolog  hybrid  hypomorphic  mammalian  polycomb  repeats  represses  repressor  silenced  t1031a  t1040c  wd40  yeast  zeste 
cpg  cues  de  dense  dnmt1  dnmts  enhancers  ensure  ensures  establishment  excluded  guide  localize  methylated  methylation  methylome  methyltransferase  methyltransferases  novo  nucleosomes  observe  preferential  promoters  pwwp  reflects  setd2  transcribed 
Tagcloud (Intersection) ?
lethal