FCHSD2 and MSL1

Number of citations of the paper that reports this interaction (PubMedID 18654987)
0

Data Source:
BioGRID (two hybrid)

		FCHSD2	MSL1
Description		FCH and double SH3 domains 2	MSL complex subunit 1
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GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Clathrin-coated Pit Membrane Neuromuscular Junction Stereocilium Cell Projection Recycling Endosome Anchoring Junction Stereocilium Shaft	Nucleus Nucleoplasm Nuclear Speck MSL Complex
	Molecular Function	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Lipid Binding Phosphatidylinositol-3,4-bisphosphate Binding	Protein Binding Protein-macromolecule Adaptor Activity
	Biological Process	Endocytosis Neuromuscular Synaptic Transmission Protein Transport Regulation Of Actin Filament Polymerization Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Cytoskeleton Organization Membrane Organization Clathrin-dependent Endocytosis Regulation Of Actin Filament Organization Positive Regulation Of Supramolecular Fiber Organization Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation	Chromatin Organization Chromatin Remodeling Positive Regulation Of DNA-templated Transcription
Pathways			HATs acetylate histones
Drugs
Diseases
GWAS		Albumin-globulin ratio ( 29403010) Crohn's disease ( 23266558 23850713) Endometrial cancer (endometrioid histology) ( 30093612) Health literacy ( 31250787) Nicotine dependence symptom count ( 25555482) Serum total protein levels ( 29403010) Systemic lupus erythematosus ( 26663301 33272962)	Asthma ( 31619474)
Interacting Genes		52 interacting genes: ABCF3 ACAP1 ANKS1A ATPAF2 BORCS6 C9orf78 CASK CCDC120 CCDC158 CCDC183 CCDC85B CCT2 CFAP36 CHKA CIMIP6 CTAG1A CTAG1B DAPP1 ENKD1 FAM9B GPRASP2 HDAC4 HGS HOMER1 HSP90AB1 HSPA5 HTRA1 ITSN1 ITSN2 KIFC3 LCA5L LDOC1 MNS1 MRFAP1 MSL1 MTUS2 PDE4DIP PRKAR1B RINT1 SASS6 SERTAD3 SH2D4A SH3BGR SRP72 TLE5 TSGA10IP USHBP1 VCPIP1 VPS37C WAS WASL ZNF587	17 interacting genes: CRKL FCHSD2 H2BC21 HORMAD1 HSPB1 KPNB1 MORF4L1 MRGBP NUPR1 PAF1 PPM1G RAN RNF20 RNF40 SMARCC1 SNW1 UBE2D3
Entrez ID		9873	339287
HPRD ID		13321	19425
Ensembl ID		ENSG00000137478	ENSG00000188895
Uniprot IDs		O94868	B3KWR7 J3KSZ8 J3QQY0 Q68DK7
PDB IDs		2DL5 2DL7 6GBU	4B7Y 4B86 4DNC
Enriched GO Terms of Interacting Partners?		TPR Domain Binding Clathrin-dependent Synaptic Vesicle Endocytosis Cytoplasm	Nucleoplasm Regulation Of Cell Cycle Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription RNA Import Into Nucleus Chromatin Binding HULC Complex Positive Regulation Of RNA Metabolic Process Nucleus Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Importin-alpha Family Protein Binding Positive Regulation Of Biosynthetic Process Chromatin Organization Positive Regulation Of Double-strand Break Repair Transcription Coactivator Activity Retinoic Acid Receptor Signaling Pathway Positive Regulation Of Macromolecule Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Nucleosome Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process NuA4 Histone Acetyltransferase Complex Positive Regulation Of DNA Repair Regulation Of Double-strand Break Repair Regulation Of RNA Metabolic Process Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of Metabolic Process Protein Localization To Nucleus Fibroblast Proliferation Reproductive Structure Development Negative Regulation Of Protein Kinase C Signaling Regulation Of Nucleobase-containing Compound Metabolic Process Stereocilium Shaft Positive Regulation Of Double-strand Break Repair Via Homologous Recombination H4/H2A Histone Acetyltransferase Complex Histone H2B C-terminal K Residue Ubiquitin Ligase Activity Regulation Of Macromolecule Metabolic Process Male Germ Cell Nucleus Developmental Process Involved In Reproduction Regulation Of DNA Repair Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Cellular Response To Stress Helper T Cell Diapedesis RNA Nuclear Export Complex SnRNA Import Into Nucleus Pre-miRNA Export From Nucleus Ubiquitin-protein Transferase Activity Regulation Of Primary Metabolic Process
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