FCHSD2 and CCDC158

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		FCHSD2	CCDC158
Gene Name		FCH and double SH3 domains 2	coiled-coil domain containing 158
Image			No pdb structure
Gene Ontology Annotations	Cellular Component
	Molecular Function	Protein Binding
	Biological Process
Pathways
Drugs
Diseases
GWAS		Crohn's disease ( 23266558)	Chronic kidney disease ( 20383146)
Protein-Protein Interactions		25 interactors: ABCF3 C2orf73 C9orf78 CASK CCDC158 CCDC85B CCT2 CFAP36 CHKA DAPP1 FAM9B HSP90AB1 HSPA5 HTRA1 ITSN1 ITSN2 KIFC3 MSL1 MTUS2 PDE4DIP SH3BGR SRP72 VCPIP1 WAS WASL	6 interactors: C1orf216 CCDC101 FCHSD2 GPSM1 NAGK SH3GLB2
Entrez ID		9873	339965
HPRD ID		13321	13395
Ensembl ID		ENSG00000137478	ENSG00000163749
Uniprot IDs		E9PG19 O94868	Q5M9N0
PDB IDs		2DL5 2DL7
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Actin Nucleation Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Arp2/3 Complex-mediated Actin Nucleation Endocytosis Regulation Of Actin Nucleation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Regulation Of Cellular Response To Growth Factor Stimulus Toxin Transport Cellular Response To Interleukin-4 Vesicle-mediated Transport Response To Interleukin-4 Regulation Of Protein Folding In Endoplasmic Reticulum Protein Complex Assembly Phagocytosis Actin Filament-based Movement Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Golgi Organization Endoplasmic Reticulum Membrane Fusion Negative Regulation Of Membrane Tubulation Cerebellum Structural Organization Transport Actin Polymerization Or Depolymerization Cellular Protein Complex Assembly Zonula Adherens Maintenance Vesicle Transport Along Actin Filament Cellular Component Assembly Ephrin Receptor Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Golgi Reassembly Dentinogenesis Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Axon Guidance Protein Localization To Endoplasmic Reticulum Positive Regulation Of Clathrin-mediated Endocytosis Movement Of Cell Or Subcellular Component Response To Unfolded Protein Immune Response-regulating Signaling Pathway Choline Metabolic Process Golgi Inheritance Protein K11-linked Deubiquitination	N-acetylmannosamine Metabolic Process N-acetylneuraminate Catabolic Process Establishment Of Protein Localization To Chromatin N-acetylneuraminate Metabolic Process Protein Localization To Chromatin N-acetylglucosamine Metabolic Process Protein Localization To Chromosome Histone H3 Acetylation Amino Sugar Metabolic Process
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