FCHSD2 and CTAG1B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FCHSD2	CTAG1B
Description		FCH and double SH3 domains 2	cancer/testis antigen 1B
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GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Clathrin-coated Pit Membrane Neuromuscular Junction Stereocilium Cell Projection Recycling Endosome Anchoring Junction Stereocilium Shaft	Cytoplasm
	Molecular Function	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Lipid Binding Phosphatidylinositol-3,4-bisphosphate Binding	Protein Binding Identical Protein Binding
	Biological Process	Endocytosis Neuromuscular Synaptic Transmission Protein Transport Regulation Of Actin Filament Polymerization Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Cytoskeleton Organization Membrane Organization Clathrin-dependent Endocytosis Regulation Of Actin Filament Organization Positive Regulation Of Supramolecular Fiber Organization Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation	TRNA Threonylcarbamoyladenosine Metabolic Process
Pathways
Drugs
Diseases
GWAS		Albumin-globulin ratio ( 29403010) Crohn's disease ( 23266558 23850713) Endometrial cancer (endometrioid histology) ( 30093612) Health literacy ( 31250787) Nicotine dependence symptom count ( 25555482) Serum total protein levels ( 29403010) Systemic lupus erythematosus ( 26663301 33272962)
Interacting Genes		52 interacting genes: ABCF3 ACAP1 ANKS1A ATPAF2 BORCS6 C9orf78 CASK CCDC120 CCDC158 CCDC183 CCDC85B CCT2 CFAP36 CHKA CIMIP6 CTAG1A CTAG1B DAPP1 ENKD1 FAM9B GPRASP2 HDAC4 HGS HOMER1 HSP90AB1 HSPA5 HTRA1 ITSN1 ITSN2 KIFC3 LCA5L LDOC1 MNS1 MRFAP1 MSL1 MTUS2 PDE4DIP PRKAR1B RINT1 SASS6 SERTAD3 SH2D4A SH3BGR SRP72 TLE5 TSGA10IP USHBP1 VCPIP1 VPS37C WAS WASL ZNF587	81 interacting genes: ACTN3 AIRIM ALOX15B ARHGEF28 ATP1A4 BAG6 BEX1 BEX2 BMF BORCS8 BORCS8-MEF2B C14orf119 CAMSAP1 CCDC116 CCHCR1 CDC37 CDKN2AIPNL CHCHD2 CSTF2T CTAG1A CYTH4 DESI1 FCHSD2 FSD2 GATC GNG13 GPSM3 GTF2I GUCD1 HCK HEMK1 HLA-DRB1 HLA-DRB3 HLA-DRB4 HLA-DRB5 KIF26A KLHL38 LAMTOR1 LNPEP LONRF3 MAGEC1 MEIS2 MGAT5B MSGN1 NAB2 NCS1 NTAQ1 P4HA3 PEF1 PIH1D2 POLM PSMB1 RANBP10 REX1BD RSRC2 RTN4IP1 RUSC1 SEC14L4 SGTA SGTB SIKE1 SMG9 SOHLH1 SPAG8 STRA8 SUOX TCEANC TEPSIN THOC1 TNPO2 TRIB3 TRIM55 TRIM63 TSGA10IP UBE2V1 UBL5 UBQLN1 UBQLN2 USP20 VENTX WWOX
Entrez ID		9873	1485
HPRD ID		13321	02151
Ensembl ID		ENSG00000137478	ENSG00000184033
Uniprot IDs		O94868	P78358
PDB IDs		2DL5 2DL7 6GBU	1S9W 2BNQ 2BNR 2F53 2F54 2P5E 2P5W 2PYE 3GJF 3HAE 3KLA 6AT5 6AVF 6AVG 6RP9 6RPA 6RPB 9C3E 9DL1
Enriched GO Terms of Interacting Partners?		TPR Domain Binding Clathrin-dependent Synaptic Vesicle Endocytosis Cytoplasm	Protein Binding Peptide Antigen Assembly With MHC Class II Protein Complex MHC Class II Protein Complex Antigen Processing And Presentation Of Exogenous Peptide Antigen Positive Regulation Of ERAD Pathway Antigen Processing And Presentation Of Exogenous Antigen Regulation Of ERAD Pathway MHC Class II Protein Complex Binding ER To Golgi Transport Vesicle Membrane Lumenal Side Of Endoplasmic Reticulum Membrane Antigen Processing And Presentation Of Exogenous Peptide Antigen Via MHC Class II Antigen Processing And Presentation Of Peptide Antigen Antigen Processing And Presentation Of Peptide Antigen Via MHC Class II Post-translational Protein Targeting To Endoplasmic Reticulum Membrane Antigen Processing And Presentation Of Peptide Or Polysaccharide Antigen Via MHC Class II Peptide Antigen Binding TRC Complex Positive Regulation Of Response To Endoplasmic Reticulum Stress Myeloid Dendritic Cell Antigen Processing And Presentation Transport Vesicle Membrane Antigen Processing And Presentation Trans-Golgi Network Membrane Skeletal Muscle Atrophy Dendritic Cell Antigen Processing And Presentation Positive Regulation Of Proteasomal Protein Catabolic Process Clathrin-coated Endocytic Vesicle Membrane Protein Targeting To ER Regulation Of Protein Ubiquitination Skeletal Muscle Adaptation Striated Muscle Atrophy Lysosomal Membrane Endocytic Vesicle Membrane Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Establishment Of Protein Localization To Endoplasmic Reticulum Autolysosome Membrane Muscle Atrophy Positive Regulation Of T Cell Mediated Immune Response To Tumor Cell MHC Class II Receptor Activity Polyubiquitin Modification-dependent Protein Binding Late Endosome Membrane Regulation Of Response To Endoplasmic Reticulum Stress ERAD Pathway Regulation Of Post-translational Protein Modification
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