FCHSD2 and CFAP36

Number of citations of the paper that reports this interaction (PubMedID 18654987)
0

Data Source:
BioGRID (two hybrid)

		FCHSD2	CFAP36
Description		FCH and double SH3 domains 2	cilia and flagella associated protein 36
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Clathrin-coated Pit Membrane Neuromuscular Junction Stereocilium Cell Projection Recycling Endosome Anchoring Junction Stereocilium Shaft	Nucleus Cytoplasm Cilium Axoneme Motile Cilium Ciliary Transition Zone Cell Projection Ciliary Base
	Molecular Function	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Lipid Binding Phosphatidylinositol-3,4-bisphosphate Binding	Protein Binding
	Biological Process	Endocytosis Neuromuscular Synaptic Transmission Protein Transport Regulation Of Actin Filament Polymerization Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Cytoskeleton Organization Membrane Organization Clathrin-dependent Endocytosis Regulation Of Actin Filament Organization Positive Regulation Of Supramolecular Fiber Organization Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways
Drugs
Diseases
GWAS		Albumin-globulin ratio ( 29403010) Crohn's disease ( 23266558 23850713) Endometrial cancer (endometrioid histology) ( 30093612) Health literacy ( 31250787) Nicotine dependence symptom count ( 25555482) Serum total protein levels ( 29403010) Systemic lupus erythematosus ( 26663301 33272962)
Interacting Genes		52 interacting genes: ABCF3 ACAP1 ANKS1A ATPAF2 BORCS6 C9orf78 CASK CCDC120 CCDC158 CCDC183 CCDC85B CCT2 CFAP36 CHKA CIMIP6 CTAG1A CTAG1B DAPP1 ENKD1 FAM9B GPRASP2 HDAC4 HGS HOMER1 HSP90AB1 HSPA5 HTRA1 ITSN1 ITSN2 KIFC3 LCA5L LDOC1 MNS1 MRFAP1 MSL1 MTUS2 PDE4DIP PRKAR1B RINT1 SASS6 SERTAD3 SH2D4A SH3BGR SRP72 TLE5 TSGA10IP USHBP1 VCPIP1 VPS37C WAS WASL ZNF587	4 interacting genes: FCHSD2 RAC1 UBC WWP2
Entrez ID		9873	112942
HPRD ID		13321	14445
Ensembl ID		ENSG00000137478	ENSG00000163001
Uniprot IDs		O94868	Q96G28
PDB IDs		2DL5 2DL7 6GBU
Enriched GO Terms of Interacting Partners?		TPR Domain Binding Clathrin-dependent Synaptic Vesicle Endocytosis Cytoplasm	Positive Regulation Of Ovarian Follicle Development Positive Regulation Of Protein Polymerization Regulation Of Actin Polymerization Or Depolymerization Negative Regulation Of Interleukin-23 Production Regulation Of Actin Filament Polymerization Regulation Of ERK5 Cascade Regulation Of Actin Filament Length Angiotensin-activated Signaling Pathway Involved In Heart Process Embryonic Olfactory Bulb Interneuron Precursor Migration Positive Regulation Of Actin Filament Polymerization Cerebral Cortex GABAergic Interneuron Development Stereocilium Shaft Positive Regulation Of Cytoskeleton Organization Rho GDP-dissociation Inhibitor Binding Positive Regulation Of Supramolecular Fiber Organization Regulation Of Cell Adhesion Involved In Heart Morphogenesis Positive Regulation Of Protein-containing Complex Assembly Regulation Of Ovarian Follicle Development Regulation Of Actin Filament Organization Auditory Receptor Cell Morphogenesis Erythrocyte Enucleation Regulation Of Cellular Component Size Engulfment Of Apoptotic Cell Tangential Migration From The Subventricular Zone To The Olfactory Bulb Negative Regulation Of Potassium Ion Export Across Plasma Membrane Kinocilium Positive Regulation Of Bicellular Tight Junction Assembly Regulation Of Interleukin-23 Production Trans-synaptic Signaling Chemical Synaptic Transmission G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Regulation Of Actin Cytoskeleton Organization Regulation Of Neuron Maturation Positive Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Thioesterase Binding Hepatocyte Growth Factor Receptor Signaling Pathway Regulation Of Skeletal Muscle Acetylcholine-gated Channel Clustering Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Potassium Channel Inhibitor Activity Synaptic Signaling Midbrain Dopaminergic Neuron Differentiation Positive Regulation Of Receptor Clustering Regulation Of Supramolecular Fiber Organization Ruffle Assembly Regulation Of Actin Filament-based Process Negative Regulation Of Fibroblast Migration Positive Regulation Of Actin Nucleation Regulation Of Potassium Ion Export Across Plasma Membrane Regulation Of Hydrogen Peroxide Metabolic Process NADPH Oxidase Complex
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