FCHSD2 and CIMIP6

Number of citations of the paper that reports this interaction (PubMedID 18654987)
0

Data Source:
BioGRID (two hybrid)

		FCHSD2	CIMIP6
Description		FCH and double SH3 domains 2	ciliary microtubule inner protein 6
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Plasma Membrane Clathrin-coated Pit Membrane Neuromuscular Junction Stereocilium Cell Projection Recycling Endosome Anchoring Junction Stereocilium Shaft	Cilium Cell Projection
	Molecular Function	Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Lipid Binding Phosphatidylinositol-3,4-bisphosphate Binding
	Biological Process	Endocytosis Neuromuscular Synaptic Transmission Protein Transport Regulation Of Actin Filament Polymerization Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Cytoskeleton Organization Membrane Organization Clathrin-dependent Endocytosis Regulation Of Actin Filament Organization Positive Regulation Of Supramolecular Fiber Organization Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Pathways
Drugs
Diseases
GWAS		Albumin-globulin ratio ( 29403010) Crohn's disease ( 23266558 23850713) Endometrial cancer (endometrioid histology) ( 30093612) Health literacy ( 31250787) Nicotine dependence symptom count ( 25555482) Serum total protein levels ( 29403010) Systemic lupus erythematosus ( 26663301 33272962)
Interacting Genes		52 interacting genes: ABCF3 ACAP1 ANKS1A ATPAF2 BORCS6 C9orf78 CASK CCDC120 CCDC158 CCDC183 CCDC85B CCT2 CFAP36 CHKA CIMIP6 CTAG1A CTAG1B DAPP1 ENKD1 FAM9B GPRASP2 HDAC4 HGS HOMER1 HSP90AB1 HSPA5 HTRA1 ITSN1 ITSN2 KIFC3 LCA5L LDOC1 MNS1 MRFAP1 MSL1 MTUS2 PDE4DIP PRKAR1B RINT1 SASS6 SERTAD3 SH2D4A SH3BGR SRP72 TLE5 TSGA10IP USHBP1 VCPIP1 VPS37C WAS WASL ZNF587	3 interacting genes: FCHSD2 HSPB1 SH3BP4
Entrez ID		9873	129852
HPRD ID		13321	13446
Ensembl ID		ENSG00000137478	ENSG00000177994
Uniprot IDs		O94868	Q8N5S3
PDB IDs		2DL5 2DL7 6GBU
Enriched GO Terms of Interacting Partners?		TPR Domain Binding Clathrin-dependent Synaptic Vesicle Endocytosis Cytoplasm	Intracellular Protein Localization Clathrin-coated Pit Unfolded Protein Binding Negative Regulation Of Protein Kinase C Signaling Stereocilium Shaft Protein Kinase C Inhibitor Activity Amino Acid Import Protein Transport Regulation Of Protein Kinase C Signaling Establishment Of Protein Localization Protein Transport Along Microtubule Anterograde Axonal Protein Transport Contractile Muscle Fiber Regulation Of Autophagy Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Actin Nucleation Regulation Of Retrograde Protein Transport, ER To Cytosol Negative Regulation Of Retrograde Protein Transport, ER To Cytosol Negative Regulation Of Protein Exit From Endoplasmic Reticulum Positive Regulation Of Endothelial Cell Chemotaxis GDP-dissociation Inhibitor Activity Negative Regulation Of GTPase Activity Endocytosis Retrograde Protein Transport, ER To Cytosol Regulation Of Protein Exit From Endoplasmic Reticulum Intracellular Protein Transport Endoplasmic Reticulum Quality Control Compartment Protein Refolding Phosphatidylinositol-3,4-bisphosphate Binding Regulation Of Arp2/3 Complex-mediated Actin Nucleation
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