ATM and ATR

  • Number of citations of the paper that reports this interaction (PMID 17124492)
  • 90
  • Data Source:
  • BioGRID (enzymatic study)

ATM

ATR

Gene Name ATM serine/threonine kinase ATR serine/threonine kinase
Image No pdb structure No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 76 interactors: AATF ABL1 AP1B1 AP2A2 AP2B1 AP3B2 ATR BCL10 BLM BRCA1 BRCA2 CDC6 CDKN2C CHD4 CHEK1 CHEK2 CREB1 CSNK1D CXXC5 DAXX DCLRE1C DDX1 DYRK2 E2F1 E4F1 EEF1E1 EIF3E EIF4EBP1 EXO1 FANCD2 FOXO3 H2AFX HIF1A KAT5 KAT8 LIG4 MCM2 MDC1 MDM2 MDM4 MRE11A NBN PARP1 PEX5 POLR2A PRKDC PTS RAD17 RAD51 RAD9A RBBP8 RHEB RNF20 RNF40 RPA1 RPA2 SMC1A SOCS1 SPSB1 STK11 TCL1A TELO2 TERF1 TERF2 TIPARP TOP1 TOPBP1 TP53 TP53BP1 TRAF6 TREX1 VPRBP WRN XPA XRCC5 ZEB1 47 interactors: AATF ABL1 AP1B1 AP2A2 ARHGEF1 ATM ATRIP BLM BRCA1 BRCA2 CDKN2C CEP164 CHD4 CHEK1 CHEK2 CLSPN CREB1 DCLRE1C DTL E2F1 E4F1 EEF1E1 EP300 FANCA FANCD2 FLT1 H2AFX KDR LIG4 MCM2 MRE11A MSH2 NBN PA2G4 PIK3CA POLD1 POLN PPP2R2A PTS RAD17 RHEB TP53 TREX1 UPF1 VPRBP XPA XRCC5
Entrez ID 472 545
HPRD ID 06347 08369
Ensembl ID ENSG00000149311 ENSG00000175054
Uniprot IDs Q13315 Q13535
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
absent  alpha  ataxia  basis  cytokines  defective  degradation  fibroblasts  fully  ikappab  immunoprecipitated  induces  ionizing  kappab  mediates  mitogens  nf  oxidants  oxidative  product  radiation  rapid  restores  stimuli  stresses  telangiectasia  tnf  transfected  understood 
activators  breakage  broad  chromatin  chromosome  comprises  concept  defect  discuss  emerging  exert  heterochromatin  hybrid  inherited  mediate  member  modulating  mr  numerous  observations  remodelling  repair  retardation  seems  segregation  snf2  somehow  thalaessemia  xnp 
Tagcloud (Difference) ?
absent  alpha  ataxia  basis  cytokines  defective  degradation  fibroblasts  fully  ikappab  immunoprecipitated  induces  ionizing  kappab  mediates  mitogens  nf  oxidants  oxidative  product  radiation  rapid  restores  stimuli  stresses  telangiectasia  tnf  transfected  understood 
activators  breakage  broad  chromatin  chromosome  comprises  concept  defect  discuss  emerging  exert  heterochromatin  hybrid  inherited  mediate  member  modulating  mr  numerous  observations  remodelling  repair  retardation  seems  segregation  snf2  somehow  thalaessemia  xnp 
Tagcloud (Intersection) ?