ATM and MDM4

  • Number of citations of the paper that reports this interaction (PMID 16163388)
  • 70
  • Data Source:
  • HPRD (in vitro, in vivo)

ATM

MDM4

Gene Name ATM serine/threonine kinase MDM4, p53 regulator
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 76 interactors: AATF ABL1 AP1B1 AP2A2 AP2B1 AP3B2 ATR BCL10 BLM BRCA1 BRCA2 CDC6 CDKN2C CHD4 CHEK1 CHEK2 CREB1 CSNK1D CXXC5 DAXX DCLRE1C DDX1 DYRK2 E2F1 E4F1 EEF1E1 EIF3E EIF4EBP1 EXO1 FANCD2 FOXO3 H2AFX HIF1A KAT5 KAT8 LIG4 MCM2 MDC1 MDM2 MDM4 MRE11A NBN PARP1 PEX5 POLR2A PRKDC PTS RAD17 RAD51 RAD9A RBBP8 RHEB RNF20 RNF40 RPA1 RPA2 SMC1A SOCS1 SPSB1 STK11 TCL1A TELO2 TERF1 TERF2 TIPARP TOP1 TOPBP1 TP53 TP53BP1 TRAF6 TREX1 VPRBP WRN XPA XRCC5 ZEB1 42 interactors: AKT1 APP ARF1 ATM CAPN7 CASP3 CD160 CDK1 CHEK1 CHEK2 CSNK1A1 E2F1 EP300 LRSAM1 MDM2 MKRN3 MNAT1 PRKAA1 RAD54B RB1 RN5S1@ RNF115 SFN SMAD3 SMAD4 SMARCA2 TP53 TP63 TP73 TRIM46 TRIM55 UBC UBE2D1 UBE2D2 UBE2D3 USP7 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ
Entrez ID 472 4194
HPRD ID 06347 04082
Ensembl ID ENSG00000149311 ENSG00000198625
Uniprot IDs Q13315 O15151 Q59FS6 Q68DC0
PDB IDs 2CR8 2VJE 2VJF 2VYR 3DAB 3EQY 3FDO 3FE7 3FEA 3JZO 3JZP 3JZQ 3LBJ 3U15
Enriched GO Terms of Interacting Partners?
Tagcloud ?
absent  alpha  ataxia  basis  cytokines  defective  degradation  fibroblasts  fully  ikappab  immunoprecipitated  induces  ionizing  kappab  mediates  mitogens  nf  oxidants  oxidative  product  radiation  rapid  restores  stimuli  stresses  telangiectasia  tnf  transfected  understood 
aberrations  abstract  along  attractive  cdk  cdk4  checkpoint  correlate  cyclind  developments  entered  highlights  kinases  logical  make  maximizing  mdm2  melanoma  melanomagenesis  p16  preliminary  rb  rb1  reactivating  reactivation  reporting  summary  targeting  video 
Tagcloud (Difference) ?
absent  alpha  ataxia  basis  cytokines  defective  degradation  fibroblasts  fully  ikappab  immunoprecipitated  induces  ionizing  kappab  mediates  mitogens  nf  oxidants  oxidative  product  radiation  rapid  restores  stimuli  stresses  telangiectasia  tnf  transfected  understood 
aberrations  abstract  along  attractive  cdk  cdk4  checkpoint  correlate  cyclind  developments  entered  highlights  kinases  logical  make  maximizing  mdm2  melanoma  melanomagenesis  p16  preliminary  rb  rb1  reactivating  reactivation  reporting  summary  targeting  video 
Tagcloud (Intersection) ?