ATM and PARP1

  • Number of citations of the paper that reports this interaction (PMID 17428792)
  • 50

ATM

PARP1

Gene Name ATM serine/threonine kinase poly (ADP-ribose) polymerase 1
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 76 interactors: AATF ABL1 AP1B1 AP2A2 AP2B1 AP3B2 ATR BCL10 BLM BRCA1 BRCA2 CDC6 CDKN2C CHD4 CHEK1 CHEK2 CREB1 CSNK1D CXXC5 DAXX DCLRE1C DDX1 DYRK2 E2F1 E4F1 EEF1E1 EIF3E EIF4EBP1 EXO1 FANCD2 FOXO3 H2AFX HIF1A KAT5 KAT8 LIG4 MCM2 MDC1 MDM2 MDM4 MRE11A NBN PARP1 PEX5 POLR2A PRKDC PTS RAD17 RAD51 RAD9A RBBP8 RHEB RNF20 RNF40 RPA1 RPA2 SMC1A SOCS1 SPSB1 STK11 TCL1A TELO2 TERF1 TERF2 TIPARP TOP1 TOPBP1 TP53 TP53BP1 TRAF6 TREX1 VPRBP WRN XPA XRCC5 ZEB1 84 interactors: APLF APTX ATM BCL2 BUB3 CASP1 CASP3 CASP7 CASP8 CD86 CDKN1A CENPA CENPB CREBBP CTSB CTSG E2F1 ERCC6 ERG FOXO1 GTF2F1 GZMB GZMM H2AFY HDAC1 HDAC3 HIST1H1A HIST1H1C HIST1H2BA HIST1H4A HIST1H4C HIST2H2AA3 HMGA1 HOXB7 HSPA2 KAT2B LIG3 LZTR1 MED14 MED6 MYBL2 NCL NCOA6 NEDD8 NFATC1 NFKB1 NPM1 NRF1 PARP2 PARP3 PCNA PIAS4 POLA1 POLA2 POLB POU2F1 PRKDC RARA RBM14 RELA RNF146 RPS3A RXRA SENP1 SENP3 SIRT1 SP1 SREK1 SUMO1 SUMO2 SUPT16H SWAP70 TCF4 TP53 TRIM29 UBE2I UHRF1 WRN XRCC1 XRCC5 XRCC6 ZBTB16 ZBTB9 ZNF423
Entrez ID 472 142
HPRD ID 06347 01435
Ensembl ID ENSG00000149311 ENSG00000143799
Uniprot IDs Q13315 P09874
PDB IDs 1UK0 1UK1 1WOK 2COK 2CR9 2CS2 2DMJ 2JVN 2L30 2L31 2RCW 2RD6 2RIQ 3GJW 3GN7 3L3L 3L3M 3OD8 3ODA 3ODC 3ODE 4AV1 4DQY 4GV7 4HHY 4HHZ 4L6S
Enriched GO Terms of Interacting Partners?
Tagcloud ?
absent  alpha  ataxia  basis  cytokines  defective  degradation  fibroblasts  fully  ikappab  immunoprecipitated  induces  ionizing  kappab  mediates  mitogens  nf  oxidants  oxidative  product  radiation  rapid  restores  stimuli  stresses  telangiectasia  tnf  transfected  understood 
ageing  ascribes  atm  attrition  brca1  complexity  ctip  ends  fusions  homologous  instability  insufficient  joining  ku70  lig3  lig4  mechanistically  nhej  overhang  rampant  relies  repeats  telomere  telomeres  telomeric  trf2  unanticipated  uncapped  underlining 
Tagcloud (Difference) ?
absent  alpha  ataxia  basis  cytokines  defective  degradation  fibroblasts  fully  ikappab  immunoprecipitated  induces  ionizing  kappab  mediates  mitogens  nf  oxidants  oxidative  product  radiation  rapid  restores  stimuli  stresses  telangiectasia  tnf  transfected  understood 
ageing  ascribes  attrition  brca1  complexity  ctip  ends  fusions  homologous  instability  insufficient  joining  ku70  lig3  lig4  mechanistically  nhej  overhang  rampant  relies  repeats  telomere  telomeres  telomeric  trf2  unanticipated  uncapped  underlining 
Tagcloud (Intersection) ?
atm