ATM and MCM2

  • Number of citations of the paper that reports this interaction (PMID 15210935)
  • 94
  • Data Source:
  • BioGRID (enzymatic study)

ATM

MCM2

Gene Name ATM serine/threonine kinase minichromosome maintenance complex component 2
Image No pdb structure No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 76 interactors: AATF ABL1 AP1B1 AP2A2 AP2B1 AP3B2 ATR BCL10 BLM BRCA1 BRCA2 CDC6 CDKN2C CHD4 CHEK1 CHEK2 CREB1 CSNK1D CXXC5 DAXX DCLRE1C DDX1 DYRK2 E2F1 E4F1 EEF1E1 EIF3E EIF4EBP1 EXO1 FANCD2 FOXO3 H2AFX HIF1A KAT5 KAT8 LIG4 MCM2 MDC1 MDM2 MDM4 MRE11A NBN PARP1 PEX5 POLR2A PRKDC PTS RAD17 RAD51 RAD9A RBBP8 RHEB RNF20 RNF40 RPA1 RPA2 SMC1A SOCS1 SPSB1 STK11 TCL1A TELO2 TERF1 TERF2 TIPARP TOP1 TOPBP1 TP53 TP53BP1 TRAF6 TREX1 VPRBP WRN XPA XRCC5 ZEB1 47 interactors: AKAP8 APP ATM ATR CCNB2 CCNC CDC6 CDC7 CDK2 CDK4 CDK6 CDKN2A CPSF1 CSNK2A1 DBF4 ELL GNB5 GTF2B GTF2H1 HIST3H3 KAT7 MCM10 MCM3 MCM4 MCM5 MCM6 MCM7 MCPH1 MOB4 MPP3 ORC1 ORC2 ORC4 ORC5 ORC6 P2RX4 PHC2 PLK1 RAD52 RPA1 RPA2 RPA3 RPS4X TBP TCEA2 TERF1 TERF2IP
Entrez ID 472 4171
HPRD ID 06347 00303
Ensembl ID ENSG00000149311 ENSG00000073111
Uniprot IDs Q13315 P49736
PDB IDs
Enriched GO Terms of Interacting Partners?
Tagcloud ?
absent  alpha  ataxia  basis  cytokines  defective  degradation  fibroblasts  fully  ikappab  immunoprecipitated  induces  ionizing  kappab  mediates  mitogens  nf  oxidants  oxidative  product  radiation  rapid  restores  stimuli  stresses  telangiectasia  tnf  transfected  understood 
1alpha  1beta  bcl2  carcinogenic  ccr2  cervices  e2  epithelia  hek293  hpv16  ikappabalpha  inflammation  intact  integration  isomerase  mediators  peptidyl  pin1  potentiated  prolyl  rela  sdf  ser727  squamous  stat3  stromal  supports  survivin  transformed 
Tagcloud (Difference) ?
absent  alpha  ataxia  basis  cytokines  defective  degradation  fibroblasts  fully  ikappab  immunoprecipitated  induces  ionizing  kappab  mediates  mitogens  nf  oxidants  oxidative  product  radiation  rapid  restores  stimuli  stresses  telangiectasia  tnf  transfected  understood 
1alpha  1beta  bcl2  carcinogenic  ccr2  cervices  e2  epithelia  hek293  hpv16  ikappabalpha  inflammation  intact  integration  isomerase  mediators  peptidyl  pin1  potentiated  prolyl  rela  sdf  ser727  squamous  stat3  stromal  supports  survivin  transformed 
Tagcloud (Intersection) ?