ATM and EIF4EBP1

  • Number of citations of the paper that reports this interaction (PMID 10608806)
  • 171
  • Data Source:
  • BioGRID (unspecified method, enzymatic study)
  • HPRD (in vitro, in vivo)

ATM

EIF4EBP1

Gene Name ATM serine/threonine kinase eukaryotic translation initiation factor 4E binding protein 1
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 76 interactors: AATF ABL1 AP1B1 AP2A2 AP2B1 AP3B2 ATR BCL10 BLM BRCA1 BRCA2 CDC6 CDKN2C CHD4 CHEK1 CHEK2 CREB1 CSNK1D CXXC5 DAXX DCLRE1C DDX1 DYRK2 E2F1 E4F1 EEF1E1 EIF3E EIF4EBP1 EXO1 FANCD2 FOXO3 H2AFX HIF1A KAT5 KAT8 LIG4 MCM2 MDC1 MDM2 MDM4 MRE11A NBN PARP1 PEX5 POLR2A PRKDC PTS RAD17 RAD51 RAD9A RBBP8 RHEB RNF20 RNF40 RPA1 RPA2 SMC1A SOCS1 SPSB1 STK11 TCL1A TELO2 TERF1 TERF2 TIPARP TOP1 TOPBP1 TP53 TP53BP1 TRAF6 TREX1 VPRBP WRN XPA XRCC5 ZEB1 32 interactors: AKT1 ATM BUB1 CHTF8 CSNK2A1 CSNK2A2 EIF4E EIF4E2 GSK3B IRAK4 LATS1 LRRK2 MAPK1 MAPK14 MAPKAP1 MAPKAPK5 MLST8 MTOR MVD PPP2CA PPP2R4 PRKCA PRKDC REL RHEBL1 RICTOR RORC RPS6KA5 RPS6KB1 RPTOR STK3 TCF4
Entrez ID 472 1978
HPRD ID 06347 03746
Ensembl ID ENSG00000149311 ENSG00000187840
Uniprot IDs Q13315 Q13541
PDB IDs 1WKW 2JGB 2JGC 2V8W 2V8X 2V8Y 3HXG 3HXI 3M93 3M94 3U7X
Enriched GO Terms of Interacting Partners?
Tagcloud ?
absent  alpha  ataxia  basis  cytokines  defective  degradation  fibroblasts  fully  ikappab  immunoprecipitated  induces  ionizing  kappab  mediates  mitogens  nf  oxidants  oxidative  product  radiation  rapid  restores  stimuli  stresses  telangiectasia  tnf  transfected  understood 
autophagy  bcl2  birc5  buffer  constituents  damaged  dataset  degrades  deregulation  distant  ero1l  fos  gapdh  gse21653  gse3494  gse7390  inc  itpr1  lived  organelles  periodicals  prognostic  proportional  shortened  signature  starvation  subgroups  vegfa  wiley 
Tagcloud (Difference) ?
absent  alpha  ataxia  basis  cytokines  defective  degradation  fibroblasts  fully  ikappab  immunoprecipitated  induces  ionizing  kappab  mediates  mitogens  nf  oxidants  oxidative  product  radiation  rapid  restores  stimuli  stresses  telangiectasia  tnf  transfected  understood 
autophagy  bcl2  birc5  buffer  constituents  damaged  dataset  degrades  deregulation  distant  ero1l  fos  gapdh  gse21653  gse3494  gse7390  inc  itpr1  lived  organelles  periodicals  prognostic  proportional  shortened  signature  starvation  subgroups  vegfa  wiley 
Tagcloud (Intersection) ?