NCK1 and TNIK

  • Number of citations of the paper that reports this interaction (PMID 10521462)
  • 29
  • Data Source:
  • HPRD (in vivo, two hybrid, in vitro)

NCK1

TNIK

Gene Name NCK adaptor protein 1 TRAF2 and NCK interacting kinase
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Brain imaging in schizophrenia (interaction) ( 19023125)
  • Coronary heart disease ( 21347282)
Protein-Protein Interactions 76 interactors: ABI1 ABL1 ADAM15 ARHGAP32 ARHGEF7 BCAR1 BLNK BRK1 CAV2 CBL CBLB CD3E CRK CSNK1G2 CYFIP2 DAG1 DCC DNM1 DOK1 DOK2 DRD3 DRD4 EGFR EIF2B2 EIF2S2 EPHB1 EPHB2 ERBB3 FASLG FGFR1 FLT1 FLT3 FRS2 GAB2 KDR KHDRBS1 KIAA1522 LCP2 LPHN2 MAP4K1 MAP4K4 MINK1 NCKAP1 NCKAP5 NCKIPSD NEDD9 NPHS1 NTRK2 PAK1 PAK2 PAK3 PDGFRB PFN1 PHC2 PKN2 PLCG1 PTK2 PXN RAC1 RASA1 RHOU RRAS SHANK3 SOCS1 SOCS7 SOS1 SYNJ2 SYNPO TBK1 TNIK TNK2 UBA52 WAS WASF1 WASL WIPF1 38 interactors: ACTG1 AGTPBP1 AKAP9 ANK2 CLU CNKSR2 DISC1 DPYSL2 DPYSL3 DST DYNC1H1 GOLGA4 GSE1 GSN HARS MACF1 NCK1 NCOR2 NEDD4 NEFM PAFAH1B1 PDE4DIP PPM1E PPP1R13B RAP2A SLC9A1 SMARCE1 SNX6 SOS1 SPTBN1 SRGAP3 SYNE1 TIAM2 TNKS TRAF2 TRIM2 TUBB2A WWC1
Entrez ID 4690 23043
HPRD ID 02740 18206
Ensembl ID ENSG00000158092 ENSG00000154310
Uniprot IDs P16333 Q9UKE5
PDB IDs 2CI8 2CI9 2CUB 2JS0 2JS2 2JW4 2X7F
Enriched GO Terms of Interacting Partners?
Tagcloud ?
adaptor  biogenesis  biosynthesis  compatible  delays  dephosphorylated  dephosphorylation  faster  homology  insulinoma  islets  juxtamembrane  littermates  min6  negatively  nonphosphorylatable  pancreatic  perk  proinsulin  protecting  proteostasis  py  regulates  sh2  threonine  transmembrane  y  y561f 
a549  attenuation  carboxamide  competition  continuing  crosstalk  docking  efforts  emerging  emt  fak  focal  hinge  ky  methylbenzamido  motility  nck  orchestrated  paxillin  pharmacologic  phenylamino  smad  tgf  thiazole  traf2  transforming  triggers  validate  wnt 
Tagcloud (Difference) ?
adaptor  biogenesis  biosynthesis  compatible  delays  dephosphorylated  dephosphorylation  faster  homology  insulinoma  islets  juxtamembrane  littermates  min6  negatively  nonphosphorylatable  pancreatic  perk  proinsulin  protecting  proteostasis  py  regulates  sh2  threonine  transmembrane  y  y561f 
a549  attenuation  carboxamide  competition  continuing  crosstalk  docking  efforts  emerging  emt  fak  focal  hinge  ky  methylbenzamido  motility  orchestrated  paxillin  pharmacologic  phenylamino  smad  tgf  thiazole  traf2  transforming  triggers  validate  wnt 
Tagcloud (Intersection) ?
nck