TNIK and GOLGA4

Number of citations of the paper that reports this interaction (PMID 17043677)
96

Data Source:
BioGRID (two hybrid)

		TNIK	GOLGA4
Gene Name		TRAF2 and NCK interacting kinase	golgin A4
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytoskeleton Apical Plasma Membrane Recycling Endosome Extracellular Vesicular Exosome	Golgi Membrane Nucleoplasm Cytoplasm Golgi Apparatus Trans-Golgi Network Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Receptor Signaling Protein Serine/threonine Kinase Activity Small GTPase Regulator Activity Protein Binding ATP Binding	Protein Binding GTPase Binding
	Biological Process	Positive Regulation Of Protein Phosphorylation Protein Phosphorylation Cytoskeleton Organization Activation Of JNKK Activity Wnt Signaling Pathway Microvillus Assembly Actin Cytoskeleton Reorganization Intracellular Signal Transduction Protein Autophosphorylation Regulation Of Dendrite Morphogenesis Protein Localization To Plasma Membrane	Protein Targeting To Golgi Vesicle-mediated Transport Golgi To Plasma Membrane Protein Transport Positive Regulation Of Axon Extension
Pathways		Oxidative Stress Induced Senescence Cellular Senescence
Drugs
Diseases
GWAS		Brain imaging in schizophrenia (interaction) ( 19023125) Coronary heart disease ( 21347282)
Protein-Protein Interactions		38 interactors: ACTG1 AGTPBP1 AKAP9 ANK2 CLU CNKSR2 DISC1 DPYSL2 DPYSL3 DST DYNC1H1 GOLGA4 GSE1 GSN HARS MACF1 NCK1 NCOR2 NEDD4 NEFM PAFAH1B1 PDE4DIP PPM1E PPP1R13B RAP2A SLC9A1 SMARCE1 SNX6 SOS1 SPTBN1 SRGAP3 SYNE1 TIAM2 TNKS TRAF2 TRIM2 TUBB2A WWC1	8 interactors: APP ARL1 ARL3 EXOC1 MACF1 RAB6A TNIK TRAF3IP1
Entrez ID		23043	2803
HPRD ID		18206	03941
Ensembl ID		ENSG00000154310	ENSG00000144674
Uniprot IDs		Q9UKE5	Q13439 Q49A56
PDB IDs		2X7F	1R4A 1UPT
Enriched GO Terms of Interacting Partners?		Neurogenesis Nervous System Development Cellular Component Assembly Movement Of Cell Or Subcellular Component Cell Differentiation Organelle Organization Generation Of Neurons Cytoskeleton Organization Regulation Of Neuron Projection Development Regulation Of Cellular Component Organization Locomotion Regulation Of Cell Projection Organization System Development Regulation Of Neuron Differentiation Anatomical Structure Development Endomembrane System Organization Regulation Of Cellular Component Size Signaling Multicellular Organismal Development Signal Transduction Cell Projection Organization Cell Communication Regulation Of Neurogenesis Cellular Localization Plasma Membrane Organization Regulation Of Signal Transduction Axonogenesis Developmental Process Positive Regulation Of Signal Transduction Axon Guidance Axon Development Cellular Response To Stimulus Cell Morphogenesis Involved In Neuron Differentiation Neuron Projection Development Cell Morphogenesis Protein Localization To Plasma Membrane Cell Projection Morphogenesis Membrane Organization Regulation Of Cell Development Regulation Of Signaling Cell Part Morphogenesis Neuron Projection Morphogenesis Neuron Differentiation Golgi To Plasma Membrane Protein Transport Anatomical Structure Morphogenesis Establishment Of Protein Localization To Plasma Membrane Establishment Or Maintenance Of Cell Polarity Cell Development Protein Localization To Organelle Cell Morphogenesis Involved In Differentiation	Cellular Localization Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Establishment Of Localization In Cell Golgi Vesicle Transport Vesicle-mediated Transport Intracellular Transport Microtubule-based Movement Protein Localization Movement Of Cell Or Subcellular Component Intraciliary Transport Microtubule-based Process Protein Localization To Golgi Apparatus Transport Retrograde Transport, Endosome To Golgi Endomembrane System Organization Cell Projection Organization Nervous System Development Post-Golgi Vesicle-mediated Transport Protein Localization To Organelle Cellular Protein Localization Regulation Of Neuron Differentiation Synaptic Growth At Neuromuscular Junction Protein Transport Establishment Of Protein Localization Small GTPase Mediated Signal Transduction Collateral Sprouting In Absence Of Injury Minus-end-directed Organelle Transport Along Microtubule Peptidyl-cysteine Methylation Generation Of Neurons Protein Localization To Plasma Membrane Regulation Of Neurogenesis Neurogenesis Collateral Sprouting Axon Midline Choice Point Recognition Organelle Organization Cilium Organization Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Intracellular Signal Transduction Endosomal Transport Signal Transduction Cell Projection Morphogenesis Axon Choice Point Recognition Regulation Of Cell Development Membrane Organization Cilium Morphogenesis Cell Part Morphogenesis Plasma Membrane Organization Posttranslational Protein Targeting To Membrane Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning
Tagcloud ?		a549 attenuation carboxamide competition continuing crosstalk docking efforts emerging emt fak focal hinge ky methylbenzamido motility nck orchestrated paxillin pharmacologic phenylamino smad tgf thiazole traf2 transforming triggers validate wnt
Tagcloud (Difference) ?		a549 attenuation carboxamide competition continuing crosstalk docking efforts emerging emt fak focal hinge ky methylbenzamido motility nck orchestrated paxillin pharmacologic phenylamino smad tgf thiazole traf2 transforming triggers validate wnt
Tagcloud (Intersection) ?