TNIK and GSE1

Number of citations of the paper that reports this interaction (PMID 17043677)
96

Data Source:
BioGRID (two hybrid)

		TNIK	GSE1
Gene Name		TRAF2 and NCK interacting kinase	Gse1 coiled-coil protein
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytoskeleton Apical Plasma Membrane Recycling Endosome Extracellular Vesicular Exosome
	Molecular Function	Protein Kinase Activity Protein Serine/threonine Kinase Activity Receptor Signaling Protein Serine/threonine Kinase Activity Small GTPase Regulator Activity Protein Binding ATP Binding	Protein Binding
	Biological Process	Positive Regulation Of Protein Phosphorylation Protein Phosphorylation Cytoskeleton Organization Activation Of JNKK Activity Wnt Signaling Pathway Microvillus Assembly Actin Cytoskeleton Reorganization Intracellular Signal Transduction Protein Autophosphorylation Regulation Of Dendrite Morphogenesis Protein Localization To Plasma Membrane
Pathways		Oxidative Stress Induced Senescence Cellular Senescence
Drugs
Diseases
GWAS		Brain imaging in schizophrenia (interaction) ( 19023125) Coronary heart disease ( 21347282)
Protein-Protein Interactions		38 interactors: ACTG1 AGTPBP1 AKAP9 ANK2 CLU CNKSR2 DISC1 DPYSL2 DPYSL3 DST DYNC1H1 GOLGA4 GSE1 GSN HARS MACF1 NCK1 NCOR2 NEDD4 NEFM PAFAH1B1 PDE4DIP PPM1E PPP1R13B RAP2A SLC9A1 SMARCE1 SNX6 SOS1 SPTBN1 SRGAP3 SYNE1 TIAM2 TNKS TRAF2 TRIM2 TUBB2A WWC1	17 interactors: C1orf94 C6orf165 CDC5L CEP63 DGCR6 EXOSC6 GOLGA2 NUDT18 RALBP1 RBM48 RBPMS RCOR3 RUNX1T1 TEKT4 TNIK TRIP6 XRCC6
Entrez ID		23043	23199
HPRD ID		18206	11066
Ensembl ID		ENSG00000154310	ENSG00000131149
Uniprot IDs		Q9UKE5	Q14687
PDB IDs		2X7F
Enriched GO Terms of Interacting Partners?		Neurogenesis Nervous System Development Cellular Component Assembly Movement Of Cell Or Subcellular Component Cell Differentiation Organelle Organization Generation Of Neurons Cytoskeleton Organization Regulation Of Neuron Projection Development Regulation Of Cellular Component Organization Locomotion Regulation Of Cell Projection Organization System Development Regulation Of Neuron Differentiation Anatomical Structure Development Endomembrane System Organization Regulation Of Cellular Component Size Signaling Multicellular Organismal Development Signal Transduction Cell Projection Organization Cell Communication Regulation Of Neurogenesis Cellular Localization Plasma Membrane Organization Regulation Of Signal Transduction Axonogenesis Developmental Process Positive Regulation Of Signal Transduction Axon Guidance Axon Development Cellular Response To Stimulus Cell Morphogenesis Involved In Neuron Differentiation Neuron Projection Development Cell Morphogenesis Protein Localization To Plasma Membrane Cell Projection Morphogenesis Membrane Organization Regulation Of Cell Development Regulation Of Signaling Cell Part Morphogenesis Neuron Projection Morphogenesis Neuron Differentiation Golgi To Plasma Membrane Protein Transport Anatomical Structure Morphogenesis Establishment Of Protein Localization To Plasma Membrane Establishment Or Maintenance Of Cell Polarity Cell Development Protein Localization To Organelle Cell Morphogenesis Involved In Differentiation	GDP Catabolic Process DGDP Catabolic Process DADP Catabolic Process RNA Metabolic Process Transcription, DNA-templated Signal Transduction In Response To DNA Damage Positive Regulation Of Protein Import Into Nucleus RNA Biosynthetic Process Gene Expression Nucleobase-containing Compound Metabolic Process Cellular Hyperosmotic Salinity Response Positive Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Protein Localization To Nucleus Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Release Of Cytoplasmic Sequestered NF-kappaB Intracellular Signal Transduction Cellular Nitrogen Compound Metabolic Process Cellular Response To X-ray Purine Ribonucleoside Diphosphate Catabolic Process Nucleobase-containing Small Molecule Catabolic Process DNA Damage Checkpoint Positive Regulation Of Intracellular Protein Transport Regulation Of Protein Import Into Nucleus Ribonucleoside Diphosphate Catabolic Process Establishment Of Integrated Proviral Latency DNA Deamination Nucleoside Diphosphate Catabolic Process Cellular Hyperosmotic Response Hyperosmotic Salinity Response Activation Of JNKK Activity Establishment Of Viral Latency Regulation Of Protein Localization To Nucleus Nitrogen Compound Metabolic Process Deoxyribonucleoside Diphosphate Metabolic Process Regulation Of Nucleocytoplasmic Transport Cellular Response To Salt Stress Centriole Replication Purine Ribonucleoside Catabolic Process Cell Cycle Checkpoint DNA Recombination Positive Regulation Of Intracellular Transport Positive Regulation Of SMAD Protein Import Into Nucleus DNA Ligation Microvillus Assembly Cellular Response To Stress Regulation Of Binding Microvillus Organization Regulation Of Intracellular Protein Transport Regulation Of SMAD Protein Import Into Nucleus
Tagcloud ?		a549 attenuation carboxamide competition continuing crosstalk docking efforts emerging emt fak focal hinge ky methylbenzamido motility nck orchestrated paxillin pharmacologic phenylamino smad tgf thiazole traf2 transforming triggers validate wnt
Tagcloud (Difference) ?		a549 attenuation carboxamide competition continuing crosstalk docking efforts emerging emt fak focal hinge ky methylbenzamido motility nck orchestrated paxillin pharmacologic phenylamino smad tgf thiazole traf2 transforming triggers validate wnt
Tagcloud (Intersection) ?