Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
TNIK and TUBB2A
Number of citations of the paper that reports this interaction (PMID
17043677
)
96
Data Source:
BioGRID
(two hybrid)
TNIK
TUBB2A
Gene Name
TRAF2 and NCK interacting kinase
tubulin, beta 2A class IIa
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytoskeleton
Apical Plasma Membrane
Recycling Endosome
Extracellular Vesicular Exosome
Nucleus
Cytoplasm
Microtubule
Vesicle
Extracellular Vesicular Exosome
Molecular Function
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Receptor Signaling Protein Serine/threonine Kinase Activity
Small GTPase Regulator Activity
Protein Binding
ATP Binding
GTPase Activity
Structural Constituent Of Cytoskeleton
GTP Binding
Biological Process
Positive Regulation Of Protein Phosphorylation
Protein Phosphorylation
Cytoskeleton Organization
Activation Of JNKK Activity
Wnt Signaling Pathway
Microvillus Assembly
Actin Cytoskeleton Reorganization
Intracellular Signal Transduction
Protein Autophosphorylation
Regulation Of Dendrite Morphogenesis
Protein Localization To Plasma Membrane
Protein Folding
Microtubule-based Process
Cellular Protein Metabolic Process
'de Novo' Posttranslational Protein Folding
Protein Polymerization
Transmembrane Transport
Pathways
Oxidative Stress Induced Senescence
Cellular Senescence
Transport of connexons to the plasma membrane
Mitotic Prometaphase
Organelle biogenesis and maintenance
Axon guidance
Hedgehog 'off' state
Separation of Sister Chromatids
Translocation of GLUT4 to the plasma membrane
G2/M Transition
L1CAM interactions
Mitotic Anaphase
Recycling pathway of L1
Recruitment of NuMA to mitotic centrosomes
Formation of tubulin folding intermediates by CCT/TriC
Intraflagellar transport
M Phase
Prefoldin mediated transfer of substrate to CCT/TriC
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding
Post-chaperonin tubulin folding pathway
Gap junction trafficking and regulation
MHC class II antigen presentation
Recruitment of mitotic centrosome proteins and complexes
Orphan transporters
Protein folding
Gap junction assembly
Gap junction trafficking
Kinesins
Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane
Assembly of the primary cilium
Factors involved in megakaryocyte development and platelet production
Cell Cycle, Mitotic
Resolution of Sister Chromatid Cohesion
Chaperonin-mediated protein folding
Signaling by Hedgehog
Centrosome maturation
Mitotic G2-G2/M phases
Mitotic Metaphase and Anaphase
Adaptive Immune System
Drugs
Diseases
GWAS
Brain imaging in schizophrenia (interaction) (
19023125
)
Coronary heart disease (
21347282
)
Protein-Protein Interactions
38 interactors:
ACTG1
AGTPBP1
AKAP9
ANK2
CLU
CNKSR2
DISC1
DPYSL2
DPYSL3
DST
DYNC1H1
GOLGA4
GSE1
GSN
HARS
MACF1
NCK1
NCOR2
NEDD4
NEFM
PAFAH1B1
PDE4DIP
PPM1E
PPP1R13B
RAP2A
SLC9A1
SMARCE1
SNX6
SOS1
SPTBN1
SRGAP3
SYNE1
TIAM2
TNKS
TRAF2
TRIM2
TUBB2A
WWC1
24 interactors:
ACD
ARL15
CHGB
DISC1
HDAC6
HGS
HMMR
LAMA4
PAFAH1B3
POT1
PSMD11
PTPRS
RABAC1
RIC8A
RPA2
RPLP1
SAT1
SDC3
SERPINB9
TERF1
TK1
TNIK
TPT1
UPF2
Entrez ID
23043
7280
HPRD ID
18206
Ensembl ID
ENSG00000154310
ENSG00000137267
Uniprot IDs
Q9UKE5
Q13885
PDB IDs
2X7F
Enriched GO Terms of Interacting Partners
?
Neurogenesis
Nervous System Development
Cellular Component Assembly
Movement Of Cell Or Subcellular Component
Cell Differentiation
Organelle Organization
Generation Of Neurons
Cytoskeleton Organization
Regulation Of Neuron Projection Development
Regulation Of Cellular Component Organization
Locomotion
Regulation Of Cell Projection Organization
System Development
Regulation Of Neuron Differentiation
Anatomical Structure Development
Endomembrane System Organization
Regulation Of Cellular Component Size
Signaling
Multicellular Organismal Development
Signal Transduction
Cell Projection Organization
Cell Communication
Regulation Of Neurogenesis
Cellular Localization
Plasma Membrane Organization
Regulation Of Signal Transduction
Axonogenesis
Developmental Process
Positive Regulation Of Signal Transduction
Axon Guidance
Axon Development
Cellular Response To Stimulus
Cell Morphogenesis Involved In Neuron Differentiation
Neuron Projection Development
Cell Morphogenesis
Protein Localization To Plasma Membrane
Cell Projection Morphogenesis
Membrane Organization
Regulation Of Cell Development
Regulation Of Signaling
Cell Part Morphogenesis
Neuron Projection Morphogenesis
Neuron Differentiation
Golgi To Plasma Membrane Protein Transport
Anatomical Structure Morphogenesis
Establishment Of Protein Localization To Plasma Membrane
Establishment Or Maintenance Of Cell Polarity
Cell Development
Protein Localization To Organelle
Cell Morphogenesis Involved In Differentiation
Negative Regulation Of Telomere Maintenance Via Telomerase
Negative Regulation Of Telomere Maintenance
Regulation Of Telomere Maintenance Via Telomerase
Regulation Of Telomerase Activity
Telomere Maintenance
Regulation Of Telomere Maintenance
Telomere Maintenance Via Telomere Lengthening
Telomere Assembly
Regulation Of DNA Biosynthetic Process
Telomere Capping
Negative Regulation Of DNA Replication
Catabolic Process
Positive Regulation Of Telomerase Activity
Telomere Maintenance Via Telomerase
Negative Regulation Of Telomerase Activity
Negative Regulation Of Chromosome Organization
Negative Regulation Of DNA Metabolic Process
Cellular Protein Localization
Positive Regulation Of DNA Biosynthetic Process
Cellular Component Assembly
RNA-dependent DNA Replication
Regulation Of DNA Replication
Negative Regulation Of DNA Biosynthetic Process
Response To Stimulus
Developmental Process
Regulation Of Proteolysis
Negative Regulation Of Mitotic Cell Cycle Phase Transition
Extracellular Matrix Organization
Extracellular Structure Organization
Regulation Of Protein Catabolic Process
Mitotic Cell Cycle Checkpoint
Glycosaminoglycan Metabolic Process
Negative Regulation Of Catalytic Activity
Regulation Of Catalytic Activity
Regulation Of Chromosome Organization
Cellular Macromolecule Catabolic Process
Cellular Localization
Pathogenesis
Cell-cell Adhesion Involved In Gastrulation
Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death
Positive Regulation Of Single-stranded Telomeric DNA Binding
Positive Regulation Of DNA Strand Elongation
Fetal Process Involved In Parturition
Hsp90 Deacetylation
Regulation Of Mitotic Cell Cycle Phase Transition
Negative Regulation Of Mitotic Cell Cycle
Homeostatic Process
Protein Localization
Intracellular Protein Transport
Regulation Of Cell Cycle Phase Transition
Tagcloud
?
a549
attenuation
carboxamide
competition
continuing
crosstalk
docking
efforts
emerging
emt
fak
focal
hinge
ky
methylbenzamido
motility
nck
orchestrated
paxillin
pharmacologic
phenylamino
smad
tgf
thiazole
traf2
transforming
triggers
validate
wnt
Tagcloud (Difference)
?
a549
attenuation
carboxamide
competition
continuing
crosstalk
docking
efforts
emerging
emt
fak
focal
hinge
ky
methylbenzamido
motility
nck
orchestrated
paxillin
pharmacologic
phenylamino
smad
tgf
thiazole
traf2
transforming
triggers
validate
wnt
Tagcloud (Intersection)
?