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TNIK and SNX6
Number of citations of the paper that reports this interaction (PMID
17043677
)
96
Data Source:
BioGRID
(two hybrid)
TNIK
SNX6
Gene Name
TRAF2 and NCK interacting kinase
sorting nexin 6
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytoskeleton
Apical Plasma Membrane
Recycling Endosome
Extracellular Vesicular Exosome
Intracellular
Nucleus
Cytoplasm
Cytoplasmic Membrane-bounded Vesicle
Extrinsic Component Of Membrane
Retromer Complex
Early Endosome Membrane
Tubular Endosome
Molecular Function
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Receptor Signaling Protein Serine/threonine Kinase Activity
Small GTPase Regulator Activity
Protein Binding
ATP Binding
Protein Binding
Dynactin Binding
Phosphatidylinositol Binding
Protein Homodimerization Activity
Biological Process
Positive Regulation Of Protein Phosphorylation
Protein Phosphorylation
Cytoskeleton Organization
Activation Of JNKK Activity
Wnt Signaling Pathway
Microvillus Assembly
Actin Cytoskeleton Reorganization
Intracellular Signal Transduction
Protein Autophosphorylation
Regulation Of Dendrite Morphogenesis
Protein Localization To Plasma Membrane
Intracellular Protein Transport
Endocytosis
Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity
Vesicle Organization
Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Retrograde Transport, Endosome To Golgi
Negative Regulation Of Transcription, DNA-templated
Regulation Of Histamine Secretion By Mast Cell
Pathways
Oxidative Stress Induced Senescence
Cellular Senescence
Drugs
Diseases
GWAS
Brain imaging in schizophrenia (interaction) (
19023125
)
Coronary heart disease (
21347282
)
Protein-Protein Interactions
38 interactors:
ACTG1
AGTPBP1
AKAP9
ANK2
CLU
CNKSR2
DISC1
DPYSL2
DPYSL3
DST
DYNC1H1
GOLGA4
GSE1
GSN
HARS
MACF1
NCK1
NCOR2
NEDD4
NEFM
PAFAH1B1
PDE4DIP
PPM1E
PPP1R13B
RAP2A
SLC9A1
SMARCE1
SNX6
SOS1
SPTBN1
SRGAP3
SYNE1
TIAM2
TNKS
TRAF2
TRIM2
TUBB2A
WWC1
22 interactors:
ACVR2B
ACVRL1
BMPR1B
BRCA1
BRMS1
CALM1
COIL
CSNK2A2
DISC1
EGFR
INSR
LEPR
NDEL1
PDGFRA
PIM1
SNX1
SNX2
SNX4
TGFBR1
TGFBR2
TNIK
TPT1
Entrez ID
23043
58533
HPRD ID
18206
12086
Ensembl ID
ENSG00000154310
ENSG00000129515
Uniprot IDs
Q9UKE5
B4DJS7
Q9UNH7
PDB IDs
2X7F
Enriched GO Terms of Interacting Partners
?
Neurogenesis
Nervous System Development
Cellular Component Assembly
Movement Of Cell Or Subcellular Component
Cell Differentiation
Organelle Organization
Generation Of Neurons
Cytoskeleton Organization
Regulation Of Neuron Projection Development
Regulation Of Cellular Component Organization
Locomotion
Regulation Of Cell Projection Organization
System Development
Regulation Of Neuron Differentiation
Anatomical Structure Development
Endomembrane System Organization
Regulation Of Cellular Component Size
Signaling
Multicellular Organismal Development
Signal Transduction
Cell Projection Organization
Cell Communication
Regulation Of Neurogenesis
Cellular Localization
Plasma Membrane Organization
Regulation Of Signal Transduction
Axonogenesis
Developmental Process
Positive Regulation Of Signal Transduction
Axon Guidance
Axon Development
Cellular Response To Stimulus
Cell Morphogenesis Involved In Neuron Differentiation
Neuron Projection Development
Cell Morphogenesis
Protein Localization To Plasma Membrane
Cell Projection Morphogenesis
Membrane Organization
Regulation Of Cell Development
Regulation Of Signaling
Cell Part Morphogenesis
Neuron Projection Morphogenesis
Neuron Differentiation
Golgi To Plasma Membrane Protein Transport
Anatomical Structure Morphogenesis
Establishment Of Protein Localization To Plasma Membrane
Establishment Or Maintenance Of Cell Polarity
Cell Development
Protein Localization To Organelle
Cell Morphogenesis Involved In Differentiation
Positive Regulation Of Protein Modification Process
Positive Regulation Of Protein Metabolic Process
Positive Regulation Of Cellular Protein Metabolic Process
Signal Transduction By Phosphorylation
Regulation Of Signaling
Developmental Process
Positive Regulation Of Kinase Activity
Regulation Of Protein Metabolic Process
Regulation Of Signal Transduction
Positive Regulation Of Transferase Activity
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Phosphorylation
Protein Phosphorylation
Positive Regulation Of Protein Kinase Activity
Positive Regulation Of Protein Phosphorylation
Positive Regulation Of Metabolic Process
Anatomical Structure Development
Phosphorylation
Intracellular Signal Transduction
Regulation Of Kinase Activity
Positive Regulation Of Cellular Metabolic Process
Enzyme Linked Receptor Protein Signaling Pathway
Multicellular Organismal Development
Regulation Of Phosphorylation
Activation Of Protein Kinase Activity
Regulation Of Protein Kinase Activity
Regulation Of Protein Phosphorylation
Anatomical Structure Morphogenesis
Regulation Of Phosphorus Metabolic Process
Positive Regulation Of Catalytic Activity
Cell Surface Receptor Signaling Pathway
Regulation Of Cell Differentiation
Cellular Protein Modification Process
Cellular Response To Growth Factor Stimulus
Regulation Of Metabolic Process
Sensory Organ Development
Camera-type Eye Development
Response To Growth Factor
Positive Regulation Of Signal Transduction
Retina Vasculature Development In Camera-type Eye
Eye Development
Phosphate-containing Compound Metabolic Process
Protein Autophosphorylation
Regulation Of Catalytic Activity
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Regulation Of Cell Proliferation
Palate Development
Activin Receptor Signaling Pathway
Chordate Embryonic Development
Embryo Development
Tagcloud
?
a549
attenuation
carboxamide
competition
continuing
crosstalk
docking
efforts
emerging
emt
fak
focal
hinge
ky
methylbenzamido
motility
nck
orchestrated
paxillin
pharmacologic
phenylamino
smad
tgf
thiazole
traf2
transforming
triggers
validate
wnt
Tagcloud (Difference)
?
a549
attenuation
carboxamide
competition
continuing
crosstalk
docking
efforts
emerging
emt
fak
focal
hinge
ky
methylbenzamido
motility
nck
orchestrated
paxillin
pharmacologic
phenylamino
smad
tgf
thiazole
traf2
transforming
triggers
validate
wnt
Tagcloud (Intersection)
?