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TNIK and CNKSR2
Number of citations of the paper that reports this interaction (PMID
17043677
)
96
Data Source:
BioGRID
(two hybrid)
TNIK
CNKSR2
Gene Name
TRAF2 and NCK interacting kinase
connector enhancer of kinase suppressor of Ras 2
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytoplasm
Cytoskeleton
Apical Plasma Membrane
Recycling Endosome
Extracellular Vesicular Exosome
Golgi Apparatus
Plasma Membrane
Neuron Projection
Neuronal Cell Body
Postsynaptic Membrane
Extracellular Vesicular Exosome
Molecular Function
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
Receptor Signaling Protein Serine/threonine Kinase Activity
Small GTPase Regulator Activity
Protein Binding
ATP Binding
Identical Protein Binding
Biological Process
Positive Regulation Of Protein Phosphorylation
Protein Phosphorylation
Cytoskeleton Organization
Activation Of JNKK Activity
Wnt Signaling Pathway
Microvillus Assembly
Actin Cytoskeleton Reorganization
Intracellular Signal Transduction
Protein Autophosphorylation
Regulation Of Dendrite Morphogenesis
Protein Localization To Plasma Membrane
Regulation Of Signal Transduction
Pathways
Oxidative Stress Induced Senescence
Cellular Senescence
Drugs
Diseases
GWAS
Brain imaging in schizophrenia (interaction) (
19023125
)
Coronary heart disease (
21347282
)
Protein-Protein Interactions
38 interactors:
ACTG1
AGTPBP1
AKAP9
ANK2
CLU
CNKSR2
DISC1
DPYSL2
DPYSL3
DST
DYNC1H1
GOLGA4
GSE1
GSN
HARS
MACF1
NCK1
NCOR2
NEDD4
NEFM
PAFAH1B1
PDE4DIP
PPM1E
PPP1R13B
RAP2A
SLC9A1
SMARCE1
SNX6
SOS1
SPTBN1
SRGAP3
SYNE1
TIAM2
TNKS
TRAF2
TRIM2
TUBB2A
WWC1
12 interactors:
DLG1
DLG2
DLG3
DLG4
INADL
LRRC7
RALA
RGS3
SHANK3
SNTA1
TJP1
TNIK
Entrez ID
23043
22866
HPRD ID
18206
06473
Ensembl ID
ENSG00000154310
ENSG00000149970
Uniprot IDs
Q9UKE5
B3KPN2
Q8WXI2
PDB IDs
2X7F
2EAN
3BS5
Enriched GO Terms of Interacting Partners
?
Neurogenesis
Nervous System Development
Cellular Component Assembly
Movement Of Cell Or Subcellular Component
Cell Differentiation
Organelle Organization
Generation Of Neurons
Cytoskeleton Organization
Regulation Of Neuron Projection Development
Regulation Of Cellular Component Organization
Locomotion
Regulation Of Cell Projection Organization
System Development
Regulation Of Neuron Differentiation
Anatomical Structure Development
Endomembrane System Organization
Regulation Of Cellular Component Size
Signaling
Multicellular Organismal Development
Signal Transduction
Cell Projection Organization
Cell Communication
Regulation Of Neurogenesis
Cellular Localization
Plasma Membrane Organization
Regulation Of Signal Transduction
Axonogenesis
Developmental Process
Positive Regulation Of Signal Transduction
Axon Guidance
Axon Development
Cellular Response To Stimulus
Cell Morphogenesis Involved In Neuron Differentiation
Neuron Projection Development
Cell Morphogenesis
Protein Localization To Plasma Membrane
Cell Projection Morphogenesis
Membrane Organization
Regulation Of Cell Development
Regulation Of Signaling
Cell Part Morphogenesis
Neuron Projection Morphogenesis
Neuron Differentiation
Golgi To Plasma Membrane Protein Transport
Anatomical Structure Morphogenesis
Establishment Of Protein Localization To Plasma Membrane
Establishment Or Maintenance Of Cell Polarity
Cell Development
Protein Localization To Organelle
Cell Morphogenesis Involved In Differentiation
Receptor Localization To Synapse
Receptor Clustering
Protein Localization To Synapse
Membrane Organization
Protein Localization To Membrane
Nucleotide Phosphorylation
Establishment Or Maintenance Of Apical/basal Cell Polarity
Cell-cell Signaling
Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Clustering
Synaptic Transmission
Regulation Of Membrane Potential
Dendritic Spine Morphogenesis
Cellular Protein Localization
Vocalization Behavior
Cell-cell Junction Assembly
Cellular Localization
Dendritic Spine Development
Regulation Of Ion Transmembrane Transport
Dendritic Spine Organization
Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity
Synapse Organization
Cortical Actin Cytoskeleton Organization
Response To External Stimulus
Postsynaptic Membrane Organization
Establishment Or Maintenance Of Cell Polarity
Phosphorylation
Cortical Cytoskeleton Organization
Signaling
Cellular Component Assembly
Regulation Of Long-term Neuronal Synaptic Plasticity
Protein Localization
Cytoskeleton Organization
Nucleotide Metabolic Process
Cell Junction Assembly
Cell Communication
Cell Projection Organization
Positive Regulation Of Excitatory Postsynaptic Membrane Potential
Cell Morphogenesis Involved In Neuron Differentiation
Cell-cell Junction Organization
Chemotaxis
Actin Cytoskeleton Organization
Regulation Of Sodium Ion Transmembrane Transport
Regulation Of Ion Transport
Neuron Projection Morphogenesis
Social Behavior
Actin Filament-based Process
Nucleobase-containing Small Molecule Metabolic Process
Positive Regulation Of Membrane Potential
Tight Junction Assembly
Cell Morphogenesis Involved In Differentiation
Tagcloud
?
a549
attenuation
carboxamide
competition
continuing
crosstalk
docking
efforts
emerging
emt
fak
focal
hinge
ky
methylbenzamido
motility
nck
orchestrated
paxillin
pharmacologic
phenylamino
smad
tgf
thiazole
traf2
transforming
triggers
validate
wnt
Tagcloud (Difference)
?
a549
attenuation
carboxamide
competition
continuing
crosstalk
docking
efforts
emerging
emt
fak
focal
hinge
ky
methylbenzamido
motility
nck
orchestrated
paxillin
pharmacologic
phenylamino
smad
tgf
thiazole
traf2
transforming
triggers
validate
wnt
Tagcloud (Intersection)
?