LEPR and SOCS3

  • Number of citations of the paper that reports this interaction (PMID 11018044)
  • 84
  • Data Source:
  • HPRD (in vitro, in vivo)

LEPR

SOCS3

Gene Name leptin receptor suppressor of cytokine signaling 3
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Blood trace element (Se levels) ( 23720494)
Protein-Protein Interactions 16 interactors: APOD CLU CSNK2B DGKZ JAK2 LEP PIN1 PTPN11 RNF41 SNX1 SNX2 SNX4 SNX6 SOCS3 STAT3 XRN1 48 interactors: ACADVL APP BCL10 BIK CSF1R CSF3R CSNK1E CUEDC2 CXCR4 EGFR EPOR GFRA1 GHR HIVEP1 IGF1R IL12RB2 IL2RB IL6ST INSR IRS1 IRS2 JAK1 JAK2 JAK3 KIAA1958 LEPR MAP1S MAPK11 MAPK6 NME4 PDPK1 PIN1 PPP3CB PRLR PTK2 PTPN11 RASA1 RBMX RNF31 RPL7A SOCS2 TCEB1 TCEB2 TES TFDP1 TFR2 TXNDC11 YES1
Entrez ID 3953 9021
HPRD ID 03001 05006
Ensembl ID ENSG00000116678 ENSG00000184557
Uniprot IDs P48357 Q4G138 O14543 Q6FI39
PDB IDs 3V6O
Enriched GO Terms of Interacting Partners?
Tagcloud ?
augmentation  avenue  confounded  constitute  conversely  cre  detrimental  dissociation  functionally  hypothalamic  hypothalamus  isolating  locomotor  melanocortin  neuroanatomically  neurochemically  neuron  obesity  opiomelanocortin  pomc  pomcneo  reactivatable  recombinase  restrict  severely  subpopulations  therapeutically  thirds  utilized 
activates  activator  ameliorate  attenuate  autoimmune  cd25lowcd44lowcd62lhigh  cd4  coculture  enhance  fate  h3k27me3  h3k4me3  immunomodulatory  immunoregulatory  inhibit  interferon  leading  manifestations  mesenchymal  msc  mscs  promoters  reciprocal  rorgammat  stat1  stat3  suppressors  th17  transducer 
Tagcloud (Difference) ?
augmentation  avenue  confounded  constitute  conversely  cre  detrimental  dissociation  functionally  hypothalamic  hypothalamus  isolating  locomotor  melanocortin  neuroanatomically  neurochemically  neuron  obesity  opiomelanocortin  pomc  pomcneo  reactivatable  recombinase  restrict  severely  subpopulations  therapeutically  thirds  utilized 
activates  activator  ameliorate  attenuate  autoimmune  cd25lowcd44lowcd62lhigh  cd4  coculture  enhance  fate  h3k27me3  h3k4me3  immunomodulatory  immunoregulatory  inhibit  interferon  leading  manifestations  mesenchymal  msc  mscs  promoters  reciprocal  rorgammat  stat1  stat3  suppressors  th17  transducer 
Tagcloud (Intersection) ?