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KCNIP3 and ADRBK1
Number of citations of the paper that reports this interaction (PMID
17102134
)
14
Data Source:
BioGRID
(pull down, enzymatic study)
KCNIP3
ADRBK1
Gene Name
Kv channel interacting protein 3, calsenilin
adrenergic, beta, receptor kinase 1
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Endoplasmic Reticulum
Golgi Apparatus
Cytosol
Plasma Membrane
Dendrite
Protein-DNA Complex
Axon Terminus
Cytoplasm
Cytosol
Plasma Membrane
Membrane
Primary Cilium
Molecular Function
DNA Binding
Transcription Corepressor Activity
Voltage-gated Ion Channel Activity
Potassium Channel Activity
Calcium Ion Binding
Protein C-terminus Binding
Potassium Channel Regulator Activity
Sequence-specific DNA Binding
Ion Channel Binding
Calcium-dependent Protein Binding
Protein Kinase Activity
G-protein Coupled Receptor Kinase Activity
Protein Binding
ATP Binding
Alpha-2A Adrenergic Receptor Binding
Edg-2 Lysophosphatidic Acid Receptor Binding
Beta-adrenergic Receptor Kinase Activity
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Transcription, DNA-templated
Regulation Of Transcription From RNA Polymerase II Promoter
Intracellular Protein Transport
Apoptotic Process
Signal Transduction
Sensory Perception Of Pain
Regulation Of Ion Transmembrane Transport
Regulation Of Neuron Apoptotic Process
Behavioral Response To Pain
Potassium Ion Transmembrane Transport
Desensitization Of G-protein Coupled Receptor Protein Signaling Pathway
Negative Regulation Of The Force Of Heart Contraction By Chemical Signal
Signal Transduction
Epidermal Growth Factor Receptor Signaling Pathway
Activation Of Phospholipase C Activity
G-protein Coupled Acetylcholine Receptor Signaling Pathway
Tachykinin Receptor Signaling Pathway
Heart Development
Fibroblast Growth Factor Receptor Signaling Pathway
Peptidyl-serine Phosphorylation
Peptidyl-threonine Phosphorylation
Receptor Internalization
Positive Regulation Of Catecholamine Secretion
Termination Of G-protein Coupled Receptor Signaling Pathway
Innate Immune Response
Negative Regulation Of Striated Muscle Contraction
Neurotrophin TRK Receptor Signaling Pathway
Cardiac Muscle Contraction
Pathways
G alpha (q) signalling events
Ca-dependent events
Signaling by GPCR
CaM pathway
Phospholipase C-mediated cascade
Signaling by FGFR in disease
Signaling by EGFRvIII in Cancer
PLCG1 events in ERBB2 signaling
DAG and IP3 signaling
CaM pathway
DAP12 signaling
Gastrin-CREB signalling pathway via PKC and MAPK
Hedgehog 'on' state
Downstream signaling of activated FGFR
Innate Immune System
Signaling by PDGF
Calmodulin induced events
Signalling by NGF
DAP12 interactions
PLC beta mediated events
Opioid Signalling
Signaling by Ligand-Responsive EGFR Variants in Cancer
NGF signalling via TRKA from the plasma membrane
G-protein mediated events
Signaling by Overexpressed Wild-Type EGFR in Cancer
Signaling by FGFR
EGFR interacts with phospholipase C-gamma
Signaling by ERBB2
G alpha (q) signalling events
Signaling by EGFR
GPCR downstream signaling
Calmodulin induced events
Downstream signal transduction
PLC-gamma1 signalling
Signaling by Hedgehog
Signaling by EGFR in Cancer
Activation of SMO
Drugs
Adenosine triphosphate
Diseases
GWAS
Protein-Protein Interactions
17 interactors:
ADRBK1
CALM2
CASP3
CD177
CLN3
CREB1
CREM
GRK6
IGF1R
IGLV3-25
IL6ST
MAVS
PCBD2
PPP3CA
PSEN1
PSEN2
TARBP2
47 interactors:
ADRA2A
ADRB2
AGTR1
AKAP12
ARRB1
BDKRB2
CAPN2
CAV1
CCR4
CCR5
CSNK2B
EGF
EGFR
EPHA2
FBXO25
FPR1
FSHR
GIT1
GIT2
GNA15
GNAQ
GNB1
GRM1
HDAC6
KCNIP3
MAPK3
MC4R
MDM2
NCS1
OPRD1
PDC
PDCL
PDE6G
PEBP1
PIK3CG
PRKACA
PRKCA
PRKCB
PRKCD
PRKCG
RASGRF1
RCVRN
RHO
RPLP2
SNCA
SRC
TPM2
Entrez ID
30818
156
HPRD ID
05232
00182
Ensembl ID
ENSG00000115041
ENSG00000173020
Uniprot IDs
Q9Y2W7
P25098
PDB IDs
2E6W
1BAK
3CIK
3KRW
3KRX
3V5W
Enriched GO Terms of Interacting Partners
?
Amyloid Precursor Protein Catabolic Process
Regulation Of Immune System Process
Negative Regulation Of Protein Phosphorylation
Cellular Response To Organic Substance
Response To Organic Substance
Positive Regulation Of Metabolic Process
Negative Regulation Of Phosphorylation
Amyloid Precursor Protein Metabolic Process
Regulation Of Protein Phosphorylation
Immune System Process
Neurotrophin TRK Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Immune Response-regulating Signaling Pathway
Negative Regulation Of Cellular Protein Metabolic Process
Cell Surface Receptor Signaling Pathway
Immune Response
Regulation Of Phosphorylation
Regulation Of Immune Response
Negative Regulation Of Protein Metabolic Process
Signal Transduction
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Cellular Metabolic Process
Cellular Response To Stimulus
Regulation Of Cellular Protein Metabolic Process
Response To Stimulus
Regulation Of Phosphorus Metabolic Process
Signaling
Negative Regulation Of Cellular Metabolic Process
Cell Communication
Regulation Of Protein Metabolic Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Signaling
Regulation Of Protein Kinase Activity
Activation Of Phospholipase C Activity
Negative Regulation Of Signaling
Regulation Of Metabolic Process
Regulation Of Catalytic Activity
Positive Regulation Of Phospholipase C Activity
Regulation Of Kinase Activity
Intracellular Signal Transduction
Negative Regulation Of Protein Kinase Activity
Response To Stress
Negative Regulation Of Kinase Activity
Protein Processing
Negative Regulation Of Apoptotic Process
Positive Regulation Of Phospholipase Activity
Negative Regulation Of Programmed Cell Death
Learning Or Memory
Cell Surface Receptor Signaling Pathway
Regulation Of Catalytic Activity
Cell Communication
Signaling
Platelet Activation
Signal Transduction
Cellular Response To Stimulus
Positive Regulation Of Catalytic Activity
Regulation Of Cellular Protein Metabolic Process
Regulation Of G-protein Coupled Receptor Protein Signaling Pathway
Response To External Stimulus
Regulation Of Signal Transduction
Regulation Of Phosphorus Metabolic Process
G-protein Coupled Receptor Signaling Pathway
Regulation Of Protein Metabolic Process
Response To Stimulus
Regulation Of Signaling
Positive Regulation Of Metabolic Process
Blood Coagulation
Hemostasis
Regulation Of Protein Phosphorylation
Response To Abiotic Stimulus
Positive Regulation Of Cellular Protein Metabolic Process
Regulation Of Phosphorylation
Regulation Of MAP Kinase Activity
Positive Regulation Of Protein Phosphorylation
Regulation Of Protein Kinase Activity
Regulation Of Intracellular Signal Transduction
Regulation Of MAPK Cascade
Positive Regulation Of Protein Modification Process
Positive Regulation Of Protein Metabolic Process
Regulation Of Kinase Activity
Positive Regulation Of Signal Transduction
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Phospholipase Activity
Cell Activation
Regulation Of Body Fluid Levels
Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway
Positive Regulation Of Phosphorylation
Wound Healing
Cellular Calcium Ion Homeostasis
Regulation Of Metabolic Process
Calcium Ion Homeostasis
Positive Regulation Of Cellular Metabolic Process
Response To Stress
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Cytosolic Calcium Ion Homeostasis
Positive Regulation Of MAPK Cascade
Positive Regulation Of Phospholipase Activity
Response To Wounding
Tagcloud
?
adrenergic
adverse
antihypertensive
atenolol
bp
diastolic
gln41leu
grk2
grk5
grks
hydrochlorothiazide
hypertensives
infarction
leu41
leukocyte
lymphoblastoid
mmhg
pharmacogenomic
protects
rs1894111
sequenced
snp
snps
sr
substudy
systolic
trandolapril
verapamil
whites
Tagcloud (Difference)
?
adrenergic
adverse
antihypertensive
atenolol
bp
diastolic
gln41leu
grk2
grk5
grks
hydrochlorothiazide
hypertensives
infarction
leu41
leukocyte
lymphoblastoid
mmhg
pharmacogenomic
protects
rs1894111
sequenced
snp
snps
sr
substudy
systolic
trandolapril
verapamil
whites
Tagcloud (Intersection)
?