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KCNIP3 and IL6ST
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
KCNIP3
IL6ST
Gene Name
Kv channel interacting protein 3, calsenilin
interleukin 6 signal transducer
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Endoplasmic Reticulum
Golgi Apparatus
Cytosol
Plasma Membrane
Dendrite
Protein-DNA Complex
Axon Terminus
Extracellular Region
Extracellular Space
Plasma Membrane
Interleukin-6 Receptor Complex
Oncostatin-M Receptor Complex
External Side Of Plasma Membrane
Membrane
Dendrite
Neuronal Cell Body
Extracellular Vesicular Exosome
Ciliary Neurotrophic Factor Receptor Complex
Molecular Function
DNA Binding
Transcription Corepressor Activity
Voltage-gated Ion Channel Activity
Potassium Channel Activity
Calcium Ion Binding
Protein C-terminus Binding
Potassium Channel Regulator Activity
Sequence-specific DNA Binding
Ion Channel Binding
Calcium-dependent Protein Binding
Ciliary Neurotrophic Factor Receptor Activity
Interleukin-6 Receptor Activity
Interleukin-11 Receptor Activity
Leukemia Inhibitory Factor Receptor Activity
Oncostatin-M Receptor Activity
Ciliary Neurotrophic Factor Receptor Binding
Interleukin-6 Receptor Binding
Protein Binding
Growth Factor Binding
Interleukin-11 Binding
Interleukin-6 Binding
Protein Homodimerization Activity
Interleukin-27 Receptor Activity
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Transcription, DNA-templated
Regulation Of Transcription From RNA Polymerase II Promoter
Intracellular Protein Transport
Apoptotic Process
Signal Transduction
Sensory Perception Of Pain
Regulation Of Ion Transmembrane Transport
Regulation Of Neuron Apoptotic Process
Behavioral Response To Pain
Potassium Ion Transmembrane Transport
Positive Regulation Of Acute Inflammatory Response
Positive Regulation Of Adaptive Immune Response
Glycogen Metabolic Process
Positive Regulation Of Cell Proliferation
Regulation Of Notch Signaling Pathway
Positive Regulation Vascular Endothelial Growth Factor Production
Positive Regulation Of Cardiac Muscle Hypertrophy
Viral Process
Cytokine-mediated Signaling Pathway
Response To Cytokine
Interleukin-11-mediated Signaling Pathway
Oncostatin-M-mediated Signaling Pathway
Positive Regulation Of T Cell Proliferation
Positive Regulation Of Tyrosine Phosphorylation Of Stat1 Protein
Positive Regulation Of Tyrosine Phosphorylation Of Stat3 Protein
Negative Regulation Of Apoptotic Process
Positive Regulation Of Osteoblast Differentiation
Positive Regulation Of Astrocyte Differentiation
Leukemia Inhibitory Factor Signaling Pathway
Interleukin-6-mediated Signaling Pathway
Negative Regulation Of Interleukin-6-mediated Signaling Pathway
Interleukin-27-mediated Signaling Pathway
Ciliary Neurotrophic Factor-mediated Signaling Pathway
Pathways
Signaling by Interleukins
Interleukin-6 signaling
Cytokine Signaling in Immune system
Drugs
Diseases
GWAS
Crohn's disease (
23128233
)
IgG glycosylation (
23382691
)
Rheumatoid arthritis (
20453842
)
Protein-Protein Interactions
17 interactors:
ADRBK1
CALM2
CASP3
CD177
CLN3
CREB1
CREM
GRK6
IGF1R
IGLV3-25
IL6ST
MAVS
PCBD2
PPP3CA
PSEN1
PSEN2
TARBP2
31 interactors:
AR
CDK9
CNTF
CNTFR
CTF1
ERBB2
ERBB3
HCK
IL31RA
IL6
IL6R
JAK1
KCNIP3
LIF
LIFR
MAGEA11
OSM
OSMR
PIK3CG
PLAUR
PRKCD
PTPN11
PTPN6
SGTB
SHC1
SOCS3
STAT3
TLE1
TYK2
UBQLN1
VAV1
Entrez ID
30818
3572
HPRD ID
05232
02824
Ensembl ID
ENSG00000115041
ENSG00000134352
Uniprot IDs
Q9Y2W7
D6RH03
P40189
Q17RA0
PDB IDs
2E6W
1BJ8
1BQU
1I1R
1N2Q
1P9M
1PVH
3L5H
3L5I
3L5J
Enriched GO Terms of Interacting Partners
?
Amyloid Precursor Protein Catabolic Process
Regulation Of Immune System Process
Negative Regulation Of Protein Phosphorylation
Cellular Response To Organic Substance
Response To Organic Substance
Positive Regulation Of Metabolic Process
Negative Regulation Of Phosphorylation
Amyloid Precursor Protein Metabolic Process
Regulation Of Protein Phosphorylation
Immune System Process
Neurotrophin TRK Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Immune Response-regulating Signaling Pathway
Negative Regulation Of Cellular Protein Metabolic Process
Cell Surface Receptor Signaling Pathway
Immune Response
Regulation Of Phosphorylation
Regulation Of Immune Response
Negative Regulation Of Protein Metabolic Process
Signal Transduction
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Cellular Metabolic Process
Cellular Response To Stimulus
Regulation Of Cellular Protein Metabolic Process
Response To Stimulus
Regulation Of Phosphorus Metabolic Process
Signaling
Negative Regulation Of Cellular Metabolic Process
Cell Communication
Regulation Of Protein Metabolic Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Signaling
Regulation Of Protein Kinase Activity
Activation Of Phospholipase C Activity
Negative Regulation Of Signaling
Regulation Of Metabolic Process
Regulation Of Catalytic Activity
Positive Regulation Of Phospholipase C Activity
Regulation Of Kinase Activity
Intracellular Signal Transduction
Negative Regulation Of Protein Kinase Activity
Response To Stress
Negative Regulation Of Kinase Activity
Protein Processing
Negative Regulation Of Apoptotic Process
Positive Regulation Of Phospholipase Activity
Negative Regulation Of Programmed Cell Death
Learning Or Memory
Cytokine-mediated Signaling Pathway
Cellular Response To Cytokine Stimulus
Cell Surface Receptor Signaling Pathway
Response To Cytokine
Cellular Response To Organic Substance
Signal Transduction
Enzyme Linked Receptor Protein Signaling Pathway
Signaling
Cellular Response To Stimulus
Regulation Of Cell Proliferation
Cell Communication
Response To Organic Substance
Positive Regulation Of Cell Proliferation
Regulation Of Peptidyl-tyrosine Phosphorylation
Regulation Of Signal Transduction
Response To Stimulus
Immune Response
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Defense Response
Regulation Of Signaling
Peptidyl-tyrosine Phosphorylation
Regulation Of Intracellular Signal Transduction
Regulation Of Cell Death
Response To Stress
Regulation Of Immune System Process
Regulation Of Phosphorylation
Regulation Of Protein Phosphorylation
Ciliary Neurotrophic Factor-mediated Signaling Pathway
Regulation Of Apoptotic Process
Regulation Of Cellular Amino Acid Metabolic Process
Regulation Of Phosphorus Metabolic Process
Immune System Process
Regulation Of Protein Metabolic Process
JAK-STAT Cascade
Positive Regulation Of Signal Transduction
Innate Immune Response
Positive Regulation Of Intracellular Signal Transduction
Positive Regulation Of Tyrosine Phosphorylation Of Stat3 Protein
Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Phosphorylation
Regulation Of Immune Response
Regulation Of Cellular Ketone Metabolic Process
Leukocyte Migration
Regulation Of Tyrosine Phosphorylation Of Stat3 Protein
Positive Regulation Of Protein Modification Process
Positive Regulation Of Protein Phosphorylation
Negative Regulation Of Cell Death
Positive Regulation Of Peptidyl-tyrosine Phosphorylation
Intracellular Signal Transduction
Regulation Of JAK-STAT Cascade
Tagcloud
?
bioinformatics
bmp2
calm1
cnaq
csf2rb
csf3
expressions
fifteen
gria2
il10ra
il10rb
il11ra
il3ra
lifr
lymphatic
microarrays
myl9
mylk
myosin
nonsmokers
nsclc
paraneoplastic
pathohistological
plcb4
ppp2ca
rac3
rock2
thbs1
verify
Tagcloud (Difference)
?
bioinformatics
bmp2
calm1
cnaq
csf2rb
csf3
expressions
fifteen
gria2
il10ra
il10rb
il11ra
il3ra
lifr
lymphatic
microarrays
myl9
mylk
myosin
nonsmokers
nsclc
paraneoplastic
pathohistological
plcb4
ppp2ca
rac3
rock2
thbs1
verify
Tagcloud (Intersection)
?