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KCNIP3 and MAVS
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
KCNIP3
MAVS
Gene Name
Kv channel interacting protein 3, calsenilin
mitochondrial antiviral signaling protein
Image
Gene Ontology Annotations
Cellular Component
Nucleus
Endoplasmic Reticulum
Golgi Apparatus
Cytosol
Plasma Membrane
Dendrite
Protein-DNA Complex
Axon Terminus
Mitochondrion
Mitochondrial Outer Membrane
Peroxisomal Membrane
Integral Component Of Membrane
Mitochondrial Membrane
Molecular Function
DNA Binding
Transcription Corepressor Activity
Voltage-gated Ion Channel Activity
Potassium Channel Activity
Calcium Ion Binding
Protein C-terminus Binding
Potassium Channel Regulator Activity
Sequence-specific DNA Binding
Ion Channel Binding
Calcium-dependent Protein Binding
Signal Transducer Activity
Protein Binding
Protein Kinase Binding
CARD Domain Binding
Biological Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter
Transcription, DNA-templated
Regulation Of Transcription From RNA Polymerase II Promoter
Intracellular Protein Transport
Apoptotic Process
Signal Transduction
Sensory Perception Of Pain
Regulation Of Ion Transmembrane Transport
Regulation Of Neuron Apoptotic Process
Behavioral Response To Pain
Potassium Ion Transmembrane Transport
Positive Regulation Of Protein Phosphorylation
Activation Of Innate Immune Response
Positive Regulation Of Defense Response To Virus By Host
Signal Transduction
Viral Process
Negative Regulation Of Type I Interferon Production
Positive Regulation Of Interferon-alpha Production
Positive Regulation Of Interferon-beta Production
Positive Regulation Of Interleukin-8 Production
Positive Regulation Of Tumor Necrosis Factor Production
Positive Regulation Of Protein Import Into Nucleus, Translocation
RIG-I Signaling Pathway
Defense Response To Bacterium
Positive Regulation Of Transcription Factor Import Into Nucleus
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Negative Regulation Of Viral Genome Replication
Innate Immune Response
Positive Regulation Of Transcription From RNA Polymerase II Promoter
Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Defense Response To Virus
Positive Regulation Of Type I Interferon-mediated Signaling Pathway
Cellular Response To Exogenous DsRNA
Positive Regulation Of Chemokine (C-C Motif) Ligand 5 Production
Positive Regulation Of IP-10 Production
Regulation Of Peroxisome Organization
Pathways
TRAF3-dependent IRF activation pathway
RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
Negative regulators of RIG-I/MDA5 signaling
TRAF6 mediated IRF7 activation
TRAF6 mediated NF-kB activation
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
17 interactors:
ADRBK1
CALM2
CASP3
CD177
CLN3
CREB1
CREM
GRK6
IGF1R
IGLV3-25
IL6ST
MAVS
PCBD2
PPP3CA
PSEN1
PSEN2
TARBP2
19 interactors:
ABL1
BAG6
CALCOCO2
DDX58
IRF3
IRF5
IRF7
KCNIP3
MAP3K7
OAS3
RIPK2
RNF5
SMURF2
STAT1
TBK1
TICAM1
TRAF5
TRAF6
UBE4A
Entrez ID
30818
57506
HPRD ID
05232
13847
Ensembl ID
ENSG00000115041
Uniprot IDs
Q9Y2W7
M1P2Z0
Q7Z434
PDB IDs
2E6W
2VGQ
Enriched GO Terms of Interacting Partners
?
Amyloid Precursor Protein Catabolic Process
Regulation Of Immune System Process
Negative Regulation Of Protein Phosphorylation
Cellular Response To Organic Substance
Response To Organic Substance
Positive Regulation Of Metabolic Process
Negative Regulation Of Phosphorylation
Amyloid Precursor Protein Metabolic Process
Regulation Of Protein Phosphorylation
Immune System Process
Neurotrophin TRK Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Immune Response-regulating Signaling Pathway
Negative Regulation Of Cellular Protein Metabolic Process
Cell Surface Receptor Signaling Pathway
Immune Response
Regulation Of Phosphorylation
Regulation Of Immune Response
Negative Regulation Of Protein Metabolic Process
Signal Transduction
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Cellular Metabolic Process
Cellular Response To Stimulus
Regulation Of Cellular Protein Metabolic Process
Response To Stimulus
Regulation Of Phosphorus Metabolic Process
Signaling
Negative Regulation Of Cellular Metabolic Process
Cell Communication
Regulation Of Protein Metabolic Process
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Regulation Of Nitrogen Compound Metabolic Process
Regulation Of Signaling
Regulation Of Protein Kinase Activity
Activation Of Phospholipase C Activity
Negative Regulation Of Signaling
Regulation Of Metabolic Process
Regulation Of Catalytic Activity
Positive Regulation Of Phospholipase C Activity
Regulation Of Kinase Activity
Intracellular Signal Transduction
Negative Regulation Of Protein Kinase Activity
Response To Stress
Negative Regulation Of Kinase Activity
Protein Processing
Negative Regulation Of Apoptotic Process
Positive Regulation Of Phospholipase Activity
Negative Regulation Of Programmed Cell Death
Learning Or Memory
Positive Regulation Of Interferon-beta Production
Regulation Of Interferon-beta Production
Positive Regulation Of Interferon-alpha Production
Innate Immune Response
Response To Other Organism
Response To Biotic Stimulus
TRIF-dependent Toll-like Receptor Signaling Pathway
Positive Regulation Of Cytokine Production
Regulation Of I-kappaB Kinase/NF-kappaB Signaling
MyD88-independent Toll-like Receptor Signaling Pathway
Toll-like Receptor 3 Signaling Pathway
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Positive Regulation Of Type I Interferon Production
Regulation Of Innate Immune Response
Activation Of Innate Immune Response
Defense Response To Virus
Toll-like Receptor 4 Signaling Pathway
Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Innate Immune Response
Immune Response
Regulation Of Type I Interferon Production
Defense Response
Toll-like Receptor Signaling Pathway
Regulation Of Cytokine Production
Response To Virus
Immune System Process
Response To Stress
Immune Response-regulating Signaling Pathway
Response To Bacterium
Response To Organic Substance
Response To Exogenous DsRNA
Regulation Of Immune Response
Positive Regulation Of Immune Response
I-kappaB Kinase/NF-kappaB Signaling
Apoptotic Process
Response To External Stimulus
Programmed Cell Death
Cellular Response To Lipopolysaccharide
Cellular Response To Organic Substance
Response To DsRNA
Cell Death
Cellular Response To Molecule Of Bacterial Origin
Death
Response To Interferon-gamma
Response To Molecule Of Bacterial Origin
Regulation Of Gene Expression
Cytoplasmic Pattern Recognition Receptor Signaling Pathway In Response To Virus
Intracellular Receptor Signaling Pathway
Positive Regulation Of Immune System Process
Tagcloud
?
2b
2c
3c
3cpro
adaptors
asp
classic
cleavage
comprises
conducts
cys
evasion
genera
glu
innate
irf3
irf7
livestock
nemo
p1
p2
picornavirus
polyproteins
preference
triad
trif
vp1
vp2
vp3
Tagcloud (Difference)
?
2b
2c
3c
3cpro
adaptors
asp
classic
cleavage
comprises
conducts
cys
evasion
genera
glu
innate
irf3
irf7
livestock
nemo
p1
p2
picornavirus
polyproteins
preference
triad
trif
vp1
vp2
vp3
Tagcloud (Intersection)
?