MAP4 and IL7R

Number of citations of the paper that reports this interaction (PMID 23151878)
3

Data Source:
BioGRID (unspecified method)

		MAP4	IL7R
Gene Name		microtubule-associated protein 4	interleukin 7 receptor
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Microtubule Microtubule Associated Complex Plasma Membrane Microtubule Cytoskeleton Extracellular Vesicular Exosome Mitotic Spindle	Extracellular Region Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Structural Molecule Activity Protein Binding Microtubule Binding Poly(A) RNA Binding	Antigen Binding Interleukin-7 Receptor Activity Protein Binding
	Biological Process	Mitotic Spindle Organization Microtubule Sliding Establishment Of Spindle Orientation Cell Division	Regulation Of DNA Recombination Cell Morphogenesis Negative Regulation Of T Cell Mediated Cytotoxicity Immunoglobulin Production Immune Response Signal Transduction Cell Surface Receptor Signaling Pathway Regulation Of Cell Size Positive Regulation Of Gene Expression Cell Growth T Cell Differentiation Positive Regulation Of T Cell Differentiation In Thymus Interleukin-7-mediated Signaling Pathway B Cell Proliferation Lymph Node Development Homeostasis Of Number Of Cells
Pathways			Signaling by Interleukins Interleukin-7 signaling Cytokine Signaling in Immune system
Drugs
Diseases
GWAS		Blood pressure ( 21909110)	Multiple sclerosis ( 21244703 19525953 21833088) Primary biliary cirrhosis ( 23000144 21399635) Type 1 diabetes ( 17554260) Ulcerative colitis ( 21297633)
Protein-Protein Interactions		16 interactors: CCNB1 CDK1 ENO2 ERBB2IP GSK3B IL7R LDLR MARK1 MARK4 NR1I3 POT1 RXRB RXRG SNTA1 TERF1 TUBB	104 interactors: ALYREF CIRBP CPSF1 CRLF2 DDX21 DDX39B DDX3X DDX5 DHX36 DHX9 EIF2AK2 ELAVL1 EMG1 FAU FUS FYN G3BP1 GNB2L1 H1FX HIST1H1C HIST1H1E HIST2H2BE HNRNPA0 HNRNPA3 HNRNPAB HNRNPC HNRNPD HNRNPDL HNRNPH3 HNRNPL HNRNPR HNRNPU HNRNPUL1 HNRNPUL2 IL2RG IL7 ILF2 ILF3 JAK1 JAK3 KIT LYN MAP4 NCL NONO PABPC1 PABPC4 PABPN1 PIK3R1 PTBP1 PTK2B PTMA PURA PURB QKI RAD21 RBM3 RBMX RPL15 RPL18 RPL22 RPL29 RPL30 RPL31 RPL6 RPL7 RPL8 RPS20 RPS3 RPSA RRAGA RSL1D1 SAFB SF1 SF3A1 SF3B1 SNRNP70 SNRPA SNRPB SNRPD1 SNRPD2 SNRPD3 SNRPE SNRPF SNRPG SRP14 SRP9 SRSF3 SRSF9 SSB STAT3 STAT5A STAT5B SYNCRIP TOE1 TOP1 TSLP U2AF1 U2AF2 YBX1 YBX3 YWHAE YWHAG ZNF787
Entrez ID		4134	3575
HPRD ID		01141	00893
Ensembl ID		ENSG00000047849	ENSG00000168685
Uniprot IDs		E7EVA0 P27816	D6RGV2 D9N160 P16871
PDB IDs			3DI2 3DI3 3UP1
Enriched GO Terms of Interacting Partners?		G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Ventricular Cardiac Muscle Cell Differentiation Negative Regulation Of Telomere Maintenance Via Telomerase Cell Cycle Striated Muscle Cell Differentiation Muscle Structure Development Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Negative Regulation Of Telomerase Activity Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Gene Expression Cell Cycle Process Positive Regulation Of Cellular Biosynthetic Process Steroid Hormone Mediated Signaling Pathway Regulation Of Telomerase Activity Regulation Of Nitrogen Compound Metabolic Process Striated Muscle Tissue Development Muscle Cell Differentiation Cardiac Muscle Cell Differentiation Muscle Tissue Development Mitotic Cell Cycle Process Positive Regulation Of Mitotic Cell Cycle Peptidyl-serine Phosphorylation Ventricular Cardiac Muscle Cell Development Regulation Of Telomere Maintenance Regulation Of DNA Replication Cardiocyte Differentiation Hormone-mediated Signaling Pathway RNA-dependent DNA Replication Mitotic Cell Cycle Positive Regulation Of Cellular Metabolic Process Cellular Response To Organic Substance Regulation Of Protein Catabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of DNA Biosynthetic Process Cellular Response To Organic Cyclic Compound Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Organelle Organization Positive Regulation Of Cellular Protein Catabolic Process Cellular Response To Lipid Positive Regulation Of Developmental Growth Cell Division G1/S Transition Of Mitotic Cell Cycle Retinoic Acid Receptor Signaling Pathway Response To Stimulus Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter	MRNA Metabolic Process MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Processing RNA Splicing MRNA Processing RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Viral Process RNA Biosynthetic Process SRP-dependent Cotranslational Protein Targeting To Membrane Termination Of RNA Polymerase II Transcription Cotranslational Protein Targeting To Membrane Protein Targeting To ER Establishment Of Protein Localization To Endoplasmic Reticulum Cellular Macromolecule Biosynthetic Process Regulation Of MRNA Stability Regulation Of RNA Stability Macromolecule Biosynthetic Process Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Protein Localization To Endoplasmic Reticulum Viral Life Cycle Cytoplasmic Transport Posttranscriptional Regulation Of Gene Expression MRNA Stabilization RNA 3'-end Processing MRNA 3'-end Processing RNA Catabolic Process Viral Transcription Cellular Metabolic Process Protein Targeting To Membrane DNA-templated Transcription, Termination Protein Targeting Nuclear-transcribed MRNA Catabolic Process Establishment Of Protein Localization To Organelle MRNA Catabolic Process Ribonucleoprotein Complex Assembly Regulation Of Translation Ribonucleoprotein Complex Biogenesis Biosynthetic Process Protein Localization To Organelle Translational Termination Establishment Of Protein Localization To Membrane Intracellular Transport Translational Elongation
Tagcloud ?		brefeldin constructs dextran dic distributions golgi impacts inducibly mock morphogenesis motility movements mt mts organellar organelle overexpress overexpressed polarization repositioning retarded stabilization stabilize stabilized steady taxol transferrin unusual vesicle	aldh1a1 anxa1 bcar1 cldn1 crmp1 endpoint folr1 foxm1 il12rb2 inconclusive kiaa1524 lox mcm7 mta1 mtdh ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1
Tagcloud (Difference) ?		brefeldin constructs dextran dic distributions golgi impacts inducibly mock morphogenesis motility movements mt mts organellar organelle overexpress overexpressed polarization repositioning retarded stabilization stabilize stabilized steady taxol transferrin unusual vesicle	aldh1a1 anxa1 bcar1 cldn1 crmp1 endpoint folr1 foxm1 il12rb2 inconclusive kiaa1524 lox mcm7 mta1 mtdh ncoa3 ndrg2 nedd9 nes overview pbk ppm1d principally prognostication qualifying slc7a5 sqstm1 warranted wnt1
Tagcloud (Intersection) ?