MAP4 and MARK1

Number of citations of the paper that reports this interaction (PMID 8631898)
30

Data Source:
HPRD (in vitro)

		MAP4	MARK1
Gene Name		microtubule-associated protein 4	MAP/microtubule affinity-regulating kinase 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Microtubule Microtubule Associated Complex Plasma Membrane Microtubule Cytoskeleton Extracellular Vesicular Exosome Mitotic Spindle	Cytoplasm Cytoskeleton Plasma Membrane Microtubule Cytoskeleton
	Molecular Function	Structural Molecule Activity Protein Binding Microtubule Binding Poly(A) RNA Binding	Magnesium Ion Binding Phosphatidylserine Binding Protein Serine/threonine Kinase Activity ATP Binding Phosphatidylinositol-4,5-bisphosphate Binding Tau-protein Kinase Activity Phosphatidic Acid Binding
	Biological Process	Mitotic Spindle Organization Microtubule Sliding Establishment Of Spindle Orientation Cell Division	Neuron Migration Protein Phosphorylation Cytoskeleton Organization Wnt Signaling Pathway Intracellular Signal Transduction
Pathways
Drugs
Diseases
GWAS		Blood pressure ( 21909110)	Bipolar disorder ( 22205951) Fat distribution (HIV) ( 21897333)
Protein-Protein Interactions		16 interactors: CCNB1 CDK1 ENO2 ERBB2IP GSK3B IL7R LDLR MARK1 MARK4 NR1I3 POT1 RXRB RXRG SNTA1 TERF1 TUBB	7 interactors: CCDC102B GJA5 MAP2 MAP4 MAPT STK11 TAOK1
Entrez ID		4134	4139
HPRD ID		01141	07353
Ensembl ID		ENSG00000047849	ENSG00000116141
Uniprot IDs		E7EVA0 P27816	B4DIB3 Q9P0L2
PDB IDs			2HAK 3OSE
Enriched GO Terms of Interacting Partners?		G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Ventricular Cardiac Muscle Cell Differentiation Negative Regulation Of Telomere Maintenance Via Telomerase Cell Cycle Striated Muscle Cell Differentiation Muscle Structure Development Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Negative Regulation Of Telomerase Activity Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Gene Expression Cell Cycle Process Positive Regulation Of Cellular Biosynthetic Process Steroid Hormone Mediated Signaling Pathway Regulation Of Telomerase Activity Regulation Of Nitrogen Compound Metabolic Process Striated Muscle Tissue Development Muscle Cell Differentiation Cardiac Muscle Cell Differentiation Muscle Tissue Development Mitotic Cell Cycle Process Positive Regulation Of Mitotic Cell Cycle Peptidyl-serine Phosphorylation Ventricular Cardiac Muscle Cell Development Regulation Of Telomere Maintenance Regulation Of DNA Replication Cardiocyte Differentiation Hormone-mediated Signaling Pathway RNA-dependent DNA Replication Mitotic Cell Cycle Positive Regulation Of Cellular Metabolic Process Cellular Response To Organic Substance Regulation Of Protein Catabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of DNA Biosynthetic Process Cellular Response To Organic Cyclic Compound Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Organelle Organization Positive Regulation Of Cellular Protein Catabolic Process Cellular Response To Lipid Positive Regulation Of Developmental Growth Cell Division G1/S Transition Of Mitotic Cell Cycle Retinoic Acid Receptor Signaling Pathway Response To Stimulus Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter	Organelle Localization Microtubule Cytoskeleton Organization Execution Phase Of Apoptosis Positive Regulation Of Axonogenesis Axonogenesis Vasomotion Microtubule Sliding AV Node Cell To Bundle Of His Cell Communication By Electrical Coupling TCR Signalosome Assembly Axon Development Cell Morphogenesis Involved In Neuron Differentiation Establishment Of Cell Polarity Neuron Projection Morphogenesis Atrial Ventricular Junction Remodeling Pulmonary Valve Formation Foramen Ovale Closure Positive Regulation Of Cell Communication By Chemical Coupling Cell Morphogenesis Involved In Differentiation Microtubule-based Process Regulation Of Axonogenesis Positive Regulation Of Cell Morphogenesis Involved In Differentiation Neuron Projection Development Cell Projection Morphogenesis Establishment Or Maintenance Of Cell Polarity Cell Part Morphogenesis Regulation Of Membrane Depolarization During Cardiac Muscle Cell Action Potential Cell Communication By Chemical Coupling Regulation Of Membrane Depolarization During Action Potential AV Node Cell To Bundle Of His Cell Communication Neuron Development Apoptotic Process Positive Regulation Of Neuron Projection Development Anatomical Structure Morphogenesis Programmed Cell Death Negative Regulation Of Glomerular Filtration Cell Cycle Process Cell Death Death Cell Morphogenesis Regulation Of Ventricular Cardiac Muscle Cell Membrane Depolarization Mitral Valve Development SA Node Cell Action Potential Regulation Of Renin Secretion Into Blood Stream Anoikis Cellular Response To UV-B Regulation Of Cardiac Muscle Cell Action Potential Bundle Of His Cell To Purkinje Myocyte Communication Neuron Differentiation Cytoskeleton Organization Activation Of Protein Kinase Activity
Tagcloud ?		brefeldin constructs dextran dic distributions golgi impacts inducibly mock morphogenesis motility movements mt mts organellar organelle overexpress overexpressed polarization repositioning retarded stabilization stabilize stabilized steady taxol transferrin unusual vesicle	backgroundprocess behavior broadly conclusionsthe coping eating engagement improvements informed intervention inverted mark0 mark2 mark5 mediators methods108 motivation motivational pmblc pmlbc question r2 resultsthe specified theoretical theoretically theories underpinning
Tagcloud (Difference) ?		brefeldin constructs dextran dic distributions golgi impacts inducibly mock morphogenesis motility movements mt mts organellar organelle overexpress overexpressed polarization repositioning retarded stabilization stabilize stabilized steady taxol transferrin unusual vesicle	backgroundprocess behavior broadly conclusionsthe coping eating engagement improvements informed intervention inverted mark0 mark2 mark5 mediators methods108 motivation motivational pmblc pmlbc question r2 resultsthe specified theoretical theoretically theories underpinning
Tagcloud (Intersection) ?