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SPERT and CDC23
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
SPERT
CDC23
Gene Name
spermatid associated
cell division cycle 23
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasmic Membrane-bounded Vesicle
Intracellular
Nucleoplasm
Anaphase-promoting Complex
Cytosol
Molecular Function
Ubiquitin-protein Transferase Activity
Biological Process
Mitotic Cell Cycle
Ubiquitin-dependent Protein Catabolic Process
Mitotic Nuclear Division
Mitotic Metaphase Plate Congression
Metaphase/anaphase Transition Of Mitotic Cell Cycle
Mitotic Spindle Assembly Checkpoint
Regulation Of Exit From Mitosis
Regulation Of Mitotic Metaphase/anaphase Transition
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Cell Division
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Protein K11-linked Ubiquitination
Pathways
Phosphorylation of the APC/C
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
Antigen processing: Ubiquitination & Proteasome degradation
Separation of Sister Chromatids
Inactivation of APC/C via direct inhibition of the APC/C complex
Cellular Senescence
Mitotic Anaphase
APC/C:Cdc20 mediated degradation of Securin
M Phase
Inactivation of APC/C via direct inhibition of the APC/C complex
Autodegradation of Cdh1 by Cdh1:APC/C
Mitotic Spindle Checkpoint
Class I MHC mediated antigen processing & presentation
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
APC/C:Cdc20 mediated degradation of mitotic proteins
Senescence-Associated Secretory Phenotype (SASP)
Regulation of APC/C activators between G1/S and early anaphase
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
Cell Cycle, Mitotic
APC/C-mediated degradation of cell cycle proteins
APC/C:Cdc20 mediated degradation of Cyclin B
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
Regulation of mitotic cell cycle
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
Cell Cycle Checkpoints
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint
Mitotic Metaphase and Anaphase
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
63 interactors:
ACTN1
ARHGEF40
ARMC7
C14orf105
C19orf44
C1orf109
CCDC146
CCNG1
CDC23
CEP44
CEP57L1
CEP95
CHCHD3
CHIC2
CKS1B
CNNM3
CTNNAL1
DGCR6
DUSP14
DZIP1L
EIF4E2
ENKD1
FAM161A
FRS3
GOLGA6L2
HAUS1
KIFC3
KLC3
LATS1
LENG1
LMO1
LMO2
LMO3
MED28
METTL17
MLH1
MMAB
MOS
NINL
PID1
PIN1
PLEKHN1
PPP1R18
RPL9
RTP5
RUNX1T1
SCNM1
SH3RF2
SYCE1
TCEANC
TCEB3
TEX11
TRIM42
TSC2
TSGA10
TUBGCP4
TXLNA
TXLNB
ZC2HC1C
ZMAT2
ZNF564
ZNF581
ZNF655
44 interactors:
ANAPC10
ANAPC13
APOL1
ATRIP
BCAS3
BYSL
CCDC24
CCDC36
CDC16
CDH1
CDT1
CEP44
COIL
CRACR2A
CTBP1
CYB5R2
DLX6-AS1
EIF5A2
FAM9B
FBXO5
GORASP2
HEMK1
INCA1
INPP5J
KCTD6
KDM1A
LZTS2
MAPK3
OPTN
PNMA5
RAC1
RAD54B
RBM15B
RBPMS
RSL24D1
SIAH1
SLC52A2
SOX5
SPERT
SSX2IP
SUV39H1
TRIM27
TSC22D4
UBE2S
Entrez ID
220082
8697
HPRD ID
14856
07221
Ensembl ID
ENSG00000174015
ENSG00000094880
Uniprot IDs
Q8NA61
Q9UJX2
PDB IDs
Enriched GO Terms of Interacting Partners
?
Cell Cycle Process
Cell Cycle
Male Meiosis Chromosome Segregation
Organelle Organization
Regulation Of Cell Cycle
Chromosome Segregation
Negative Regulation Of Phosphorylation
Negative Regulation Of Cellular Metabolic Process
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Cell Division
Synapsis
Homologous Chromosome Segregation
Negative Regulation Of Cell Cycle
Resolution Of Meiotic Recombination Intermediates
Negative Regulation Of MAPK Cascade
Mitotic Cell Cycle Process
Regulation Of Phosphorus Metabolic Process
Microtubule-based Process
Mitotic Cell Cycle
Meiotic Chromosome Segregation
Meiotic Cell Cycle
Regulation Of Phosphorylation
Chromosome Separation
Regulation Of Protein Phosphorylation
Synaptonemal Complex Assembly
Regulation Of Cell Cycle Phase Transition
Regulation Of Mitotic Cell Cycle
Synaptonemal Complex Organization
Meiosis I
Regulation Of Metabolic Process
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Microtubule Cytoskeleton Organization
Gene Expression
G2/M Transition Of Mitotic Cell Cycle
Metaphase Plate Congression
Spindle Organization
Positive Regulation Of Glucocorticoid Receptor Signaling Pathway
Meiotic Metaphase I Plate Congression
Negative Regulation Of Mitochondrial DNA Replication
Meiotic Spindle Midzone Assembly
Establishment Of Meiotic Spindle Orientation
Negative Regulation Of Metaphase/anaphase Transition Of Meiotic Cell Cycle
Regulation Of Cell Cycle Process
Negative Regulation Of Protein Serine/threonine Kinase Activity
Cellular Component Assembly
Negative Regulation Of Transferase Activity
Regulation Of Protein Kinase Activity
Negative Regulation Of Insulin Receptor Signaling Pathway
Mitotic Nuclear Division
Protein K11-linked Ubiquitination
Cell Cycle
Regulation Of Organelle Organization
Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Ligase Activity
Mitotic Cell Cycle
Protein Polyubiquitination
Regulation Of Ubiquitin-protein Transferase Activity
Cell Cycle Process
Mitotic Nuclear Division
Regulation Of Cellular Protein Metabolic Process
Mitotic Cell Cycle Process
Regulation Of Chromosome Organization
Organelle Organization
Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Regulation Of Protein Metabolic Process
Positive Regulation Of Protein Ubiquitination
Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Negative Regulation Of Cellular Protein Metabolic Process
Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle
Negative Regulation Of Ubiquitin-protein Transferase Activity
Cell Division
Positive Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Protein Metabolic Process
Negative Regulation Of Transferase Activity
Positive Regulation Of Protein Modification Process
Negative Regulation Of Cellular Metabolic Process
Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Protein Metabolic Process
Negative Regulation Of Chromosome Organization
Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process
Regulation Of Protein Ubiquitination
Regulation Of Cellular Component Organization
Negative Regulation Of Protein Ubiquitination
Positive Regulation Of Transferase Activity
Protein Ubiquitination
Cell Cycle Checkpoint
Protein Modification By Small Protein Conjugation
Activation Of Anaphase-promoting Complex Activity
Regulation Of Mitotic Sister Chromatid Separation
Positive Regulation Of Cellular Metabolic Process
Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process
Positive Regulation Of Cellular Protein Catabolic Process
Regulation Of Metabolic Process
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Tagcloud
?
34c
annexin
arrest
atlas
basal
breast
ccnd1
cdk4
cdk6
downregulated
ectopic
g2
incorporation
inducing
influenced
mediator
microrna
mimicked
mir
mirna
mirnas
mitotic
prkca
qpcr
sirnas
suppressed
suppressor
tcga
thymidine
Tagcloud (Difference)
?
34c
annexin
arrest
atlas
basal
breast
ccnd1
cdk4
cdk6
downregulated
ectopic
g2
incorporation
inducing
influenced
mediator
microrna
mimicked
mir
mirna
mirnas
mitotic
prkca
qpcr
sirnas
suppressed
suppressor
tcga
thymidine
Tagcloud (Intersection)
?