SPERT and FRS3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SPERT	FRS3
Gene Name		spermatid associated	fibroblast growth factor receptor substrate 3
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasmic Membrane-bounded Vesicle	Plasma Membrane
	Molecular Function		Fibroblast Growth Factor Receptor Binding Insulin Receptor Binding Protein Binding
	Biological Process		Signal Transduction Fibroblast Growth Factor Receptor Signaling Pathway
Pathways			Signaling by FGFR in disease FRS2-mediated cascade Downstream signaling of activated FGFR Signaling by FGFR
Drugs
Diseases
GWAS
Protein-Protein Interactions		63 interactors: ACTN1 ARHGEF40 ARMC7 C14orf105 C19orf44 C1orf109 CCDC146 CCNG1 CDC23 CEP44 CEP57L1 CEP95 CHCHD3 CHIC2 CKS1B CNNM3 CTNNAL1 DGCR6 DUSP14 DZIP1L EIF4E2 ENKD1 FAM161A FRS3 GOLGA6L2 HAUS1 KIFC3 KLC3 LATS1 LENG1 LMO1 LMO2 LMO3 MED28 METTL17 MLH1 MMAB MOS NINL PID1 PIN1 PLEKHN1 PPP1R18 RPL9 RTP5 RUNX1T1 SCNM1 SH3RF2 SYCE1 TCEANC TCEB3 TEX11 TRIM42 TSC2 TSGA10 TUBGCP4 TXLNA TXLNB ZC2HC1C ZMAT2 ZNF564 ZNF581 ZNF655	20 interactors: ADAMTSL4 AES BMPR2 FGFR1 GATA1 GRB2 KARS MAPK1 NOTCH2NL NTRK1 NTRK2 PLSCR1 PRKCI PTPN11 RFX6 RND1 SPERT SPRY2 TCF4 TRIP6
Entrez ID		220082	10817
HPRD ID		14856	06373
Ensembl ID		ENSG00000174015	ENSG00000137218
Uniprot IDs		Q8NA61	O43559
PDB IDs			2KUP 2KUQ 2YS5 2YT2
Enriched GO Terms of Interacting Partners?		Cell Cycle Process Cell Cycle Male Meiosis Chromosome Segregation Organelle Organization Regulation Of Cell Cycle Chromosome Segregation Negative Regulation Of Phosphorylation Negative Regulation Of Cellular Metabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cell Division Synapsis Homologous Chromosome Segregation Negative Regulation Of Cell Cycle Resolution Of Meiotic Recombination Intermediates Negative Regulation Of MAPK Cascade Mitotic Cell Cycle Process Regulation Of Phosphorus Metabolic Process Microtubule-based Process Mitotic Cell Cycle Meiotic Chromosome Segregation Meiotic Cell Cycle Regulation Of Phosphorylation Chromosome Separation Regulation Of Protein Phosphorylation Synaptonemal Complex Assembly Regulation Of Cell Cycle Phase Transition Regulation Of Mitotic Cell Cycle Synaptonemal Complex Organization Meiosis I Regulation Of Metabolic Process Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Microtubule Cytoskeleton Organization Gene Expression G2/M Transition Of Mitotic Cell Cycle Metaphase Plate Congression Spindle Organization Positive Regulation Of Glucocorticoid Receptor Signaling Pathway Meiotic Metaphase I Plate Congression Negative Regulation Of Mitochondrial DNA Replication Meiotic Spindle Midzone Assembly Establishment Of Meiotic Spindle Orientation Negative Regulation Of Metaphase/anaphase Transition Of Meiotic Cell Cycle Regulation Of Cell Cycle Process Negative Regulation Of Protein Serine/threonine Kinase Activity Cellular Component Assembly Negative Regulation Of Transferase Activity Regulation Of Protein Kinase Activity Negative Regulation Of Insulin Receptor Signaling Pathway Mitotic Nuclear Division	Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Anatomical Structure Morphogenesis Regulation Of Signaling Cellular Response To Growth Factor Stimulus Response To Growth Factor Cell Differentiation Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Signal Transduction Regulation Of Signal Transduction Cell Development Response To External Stimulus Organ Development Positive Regulation Of Protein Phosphorylation Response To Organic Substance Multicellular Organismal Development Positive Regulation Of Cellular Metabolic Process Generation Of Neurons Positive Regulation Of Intracellular Signal Transduction System Development Positive Regulation Of Neuron Differentiation Neurogenesis Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Phosphorylation Positive Regulation Of Protein Metabolic Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Positive Regulation Of Protein Modification Process Regulation Of Phosphorylation Cellular Response To Fibroblast Growth Factor Stimulus Regulation Of MAPK Cascade Response To Fibroblast Growth Factor Neuron Development Developmental Process Intracellular Signal Transduction Axon Guidance Organ Morphogenesis Positive Regulation Of Neurogenesis Cell Surface Receptor Signaling Pathway Signaling Cellular Response To Insulin Stimulus Regulation Of Apoptotic Process Regulation Of Phosphorus Metabolic Process Regulation Of Cell Proliferation Positive Regulation Of Neuron Projection Development Cell Communication Regulation Of Protein Phosphorylation Cell Morphogenesis Involved In Differentiation Epithelium Development
Tagcloud ?			2yf 4yf adapters alleviated anophthalmia coordinated ectodermal embryogenesis eye fgf fgfr laevis maternally microphthalmia mo morphants morpholino oligonucleotide pax6 pi3 placode rescue served shp2 vertebrate xenopus xfrs3 zygotically
Tagcloud (Difference) ?			2yf 4yf adapters alleviated anophthalmia coordinated ectodermal embryogenesis eye fgf fgfr laevis maternally microphthalmia mo morphants morpholino oligonucleotide pax6 pi3 placode rescue served shp2 vertebrate xenopus xfrs3 zygotically
Tagcloud (Intersection) ?