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SPERT and ACTN1
Number of citations of the paper that reports this interaction (PMID
25416956
)
0
Data Source:
BioGRID
(two hybrid)
SPERT
ACTN1
Gene Name
spermatid associated
actinin, alpha 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Cytoplasmic Membrane-bounded Vesicle
Stress Fiber
Ruffle
Extracellular Region
Extracellular Space
Nucleus
Cytoplasm
Cytosol
Plasma Membrane
Fascia Adherens
Focal Adhesion
Z Disc
Cortical Actin Cytoskeleton
Platelet Alpha Granule Lumen
Pseudopodium
Cell Projection
Dendritic Spine
Extracellular Vesicular Exosome
Molecular Function
Double-stranded RNA Binding
Integrin Binding
Calcium Ion Binding
Protein Binding
Vinculin Binding
Protein Domain Specific Binding
Ligand-dependent Nuclear Receptor Transcription Coactivator Activity
Ion Channel Binding
Actin Filament Binding
Biological Process
Platelet Degranulation
Blood Coagulation
Platelet Activation
Extracellular Matrix Organization
Cell Junction Assembly
Regulation Of Apoptotic Process
Focal Adhesion Assembly
Actin Filament Bundle Assembly
Negative Regulation Of Cellular Component Movement
Actin Crosslink Formation
Regulation Of Nucleic Acid-templated Transcription
Pathways
Cell junction organization
Syndecan interactions
Response to elevated platelet cytosolic Ca2+
Regulation of cytoskeletal remodeling and cell spreading by IPP complex components
Nephrin interactions
Platelet degranulation
Non-integrin membrane-ECM interactions
Platelet activation, signaling and aggregation
Cell-extracellular matrix interactions
Drugs
Diseases
GWAS
Prostate cancer (
23535732
)
Smoking behavior (
19247474
)
Protein-Protein Interactions
63 interactors:
ACTN1
ARHGEF40
ARMC7
C14orf105
C19orf44
C1orf109
CCDC146
CCNG1
CDC23
CEP44
CEP57L1
CEP95
CHCHD3
CHIC2
CKS1B
CNNM3
CTNNAL1
DGCR6
DUSP14
DZIP1L
EIF4E2
ENKD1
FAM161A
FRS3
GOLGA6L2
HAUS1
KIFC3
KLC3
LATS1
LENG1
LMO1
LMO2
LMO3
MED28
METTL17
MLH1
MMAB
MOS
NINL
PID1
PIN1
PLEKHN1
PPP1R18
RPL9
RTP5
RUNX1T1
SCNM1
SH3RF2
SYCE1
TCEANC
TCEB3
TEX11
TRIM42
TSC2
TSGA10
TUBGCP4
TXLNA
TXLNB
ZC2HC1C
ZMAT2
ZNF564
ZNF581
ZNF655
70 interactors:
ACTN3
ADORA2A
APC
ATXN2
ATXN7
CACNA1A
CAMK2A
CDK5
CDK5R1
CDK5R2
CLIC5
COIL
COL17A1
CSRP1
CSRP3
CTNNA1
EPM2AIP1
ERBB2IP
FBP1
FXN
GFI1B
GIPC1
GIT2
GRIA4
GRIN2A
GTF2H1
ITGB1
KAT2B
KCTD6
KPNA2
LPP
MAGEA11
MAP2
MAP3K1
MED14
MICALL2
MYOT
MYOZ1
MYOZ2
MYOZ3
NEBL
NR1H3
NUMBL
OAS1
PALLD
PDHX
PDLIM1
PDLIM5
PIAS4
PKD1
PKN1
PLD2
PSEN1
PSMA1
PTK2
PTPN1
PTPN6
PYGB
RAVER1
RPS27
SLC2A4
SORBS2
SPERT
SRC
SSX2IP
TES
TTN
VCL
XRCC4
ZYX
Entrez ID
220082
87
HPRD ID
14856
00020
Ensembl ID
ENSG00000174015
ENSG00000072110
Uniprot IDs
Q8NA61
P12814
PDB IDs
2EYI
2EYN
Enriched GO Terms of Interacting Partners
?
Cell Cycle Process
Cell Cycle
Male Meiosis Chromosome Segregation
Organelle Organization
Regulation Of Cell Cycle
Chromosome Segregation
Negative Regulation Of Phosphorylation
Negative Regulation Of Cellular Metabolic Process
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Cell Division
Synapsis
Homologous Chromosome Segregation
Negative Regulation Of Cell Cycle
Resolution Of Meiotic Recombination Intermediates
Negative Regulation Of MAPK Cascade
Mitotic Cell Cycle Process
Regulation Of Phosphorus Metabolic Process
Microtubule-based Process
Mitotic Cell Cycle
Meiotic Chromosome Segregation
Meiotic Cell Cycle
Regulation Of Phosphorylation
Chromosome Separation
Regulation Of Protein Phosphorylation
Synaptonemal Complex Assembly
Regulation Of Cell Cycle Phase Transition
Regulation Of Mitotic Cell Cycle
Synaptonemal Complex Organization
Meiosis I
Regulation Of Metabolic Process
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Microtubule Cytoskeleton Organization
Gene Expression
G2/M Transition Of Mitotic Cell Cycle
Metaphase Plate Congression
Spindle Organization
Positive Regulation Of Glucocorticoid Receptor Signaling Pathway
Meiotic Metaphase I Plate Congression
Negative Regulation Of Mitochondrial DNA Replication
Meiotic Spindle Midzone Assembly
Establishment Of Meiotic Spindle Orientation
Negative Regulation Of Metaphase/anaphase Transition Of Meiotic Cell Cycle
Regulation Of Cell Cycle Process
Negative Regulation Of Protein Serine/threonine Kinase Activity
Cellular Component Assembly
Negative Regulation Of Transferase Activity
Regulation Of Protein Kinase Activity
Negative Regulation Of Insulin Receptor Signaling Pathway
Mitotic Nuclear Division
Cytoskeleton Organization
Cell Adhesion
Cellular Component Assembly
Organelle Organization
Cell Development
Regulation Of Protein Kinase Activity
Actin Filament-based Process
Regulation Of Kinase Activity
Regulation Of Cellular Protein Metabolic Process
Actin Cytoskeleton Organization
Cell Morphogenesis Involved In Differentiation
Regulation Of Protein Metabolic Process
Cell-substrate Adhesion
Anatomical Structure Morphogenesis
Neurogenesis
Regulation Of Phosphorus Metabolic Process
Cell Differentiation
Generation Of Neurons
Cell Morphogenesis
Regulation Of Protein Phosphorylation
Response To Stress
Actomyosin Structure Organization
Neuron Development
Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Regulation Of Catalytic Activity
Central Nervous System Development
Positive Regulation Of Transferase Activity
Regulation Of Signaling
Response To Stimulus
Response To Wounding
Regulation Of Phosphorylation
Cell-cell Junction Organization
Regulation Of Cell Projection Organization
Nervous System Development
Anatomical Structure Formation Involved In Morphogenesis
Single Organismal Cell-cell Adhesion
Adherens Junction Organization
Neuron Projection Development
Neuron Differentiation
Anatomical Structure Development
Blood Coagulation
Cell Surface Receptor Signaling Pathway
Cell Projection Organization
Hemostasis
Cell-matrix Adhesion
Apical Junction Assembly
Cell Morphogenesis Involved In Neuron Differentiation
Regulation Of Signal Transduction
Regulation Of Cell Death
Regulation Of Neuron Projection Development
Tagcloud
?
b5
bcat1
carbamoyl
ctnnd1
egfr1
eph
filamin
flna
genego
i2d
interactors
interologous
metadherin
mtdh
nucleolin
pathwaycommons
plec
plectin
pycard
pyd
rpkm
s100a2
serpinb5
signalings
stratifin
subpathway
sum149
sum190
tfrc
Tagcloud (Difference)
?
b5
bcat1
carbamoyl
ctnnd1
egfr1
eph
filamin
flna
genego
i2d
interactors
interologous
metadherin
mtdh
nucleolin
pathwaycommons
plec
plectin
pycard
pyd
rpkm
s100a2
serpinb5
signalings
stratifin
subpathway
sum149
sum190
tfrc
Tagcloud (Intersection)
?