SPERT and DUSP14

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SPERT	DUSP14
Gene Name		spermatid associated	dual specificity phosphatase 14
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasmic Membrane-bounded Vesicle
	Molecular Function		Protein Tyrosine Phosphatase Activity Protein Tyrosine/serine/threonine Phosphatase Activity MAP Kinase Tyrosine/serine/threonine Phosphatase Activity Poly(A) RNA Binding
	Biological Process		Inactivation Of MAPK Activity Peptidyl-tyrosine Dephosphorylation
Pathways
Drugs
Diseases
GWAS			Ovarian cancer ( 23535730)
Protein-Protein Interactions		63 interactors: ACTN1 ARHGEF40 ARMC7 C14orf105 C19orf44 C1orf109 CCDC146 CCNG1 CDC23 CEP44 CEP57L1 CEP95 CHCHD3 CHIC2 CKS1B CNNM3 CTNNAL1 DGCR6 DUSP14 DZIP1L EIF4E2 ENKD1 FAM161A FRS3 GOLGA6L2 HAUS1 KIFC3 KLC3 LATS1 LENG1 LMO1 LMO2 LMO3 MED28 METTL17 MLH1 MMAB MOS NINL PID1 PIN1 PLEKHN1 PPP1R18 RPL9 RTP5 RUNX1T1 SCNM1 SH3RF2 SYCE1 TCEANC TCEB3 TEX11 TRIM42 TSC2 TSGA10 TUBGCP4 TXLNA TXLNB ZC2HC1C ZMAT2 ZNF564 ZNF581 ZNF655	4 interactors: CD28 ISYNA1 SPERT UCHL5
Entrez ID		220082	11072
HPRD ID		14856	09427
Ensembl ID		ENSG00000174015	ENSG00000161326
Uniprot IDs		Q8NA61	O95147 Q6FI36
PDB IDs			2WGP
Enriched GO Terms of Interacting Partners?		Cell Cycle Process Cell Cycle Male Meiosis Chromosome Segregation Organelle Organization Regulation Of Cell Cycle Chromosome Segregation Negative Regulation Of Phosphorylation Negative Regulation Of Cellular Metabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cell Division Synapsis Homologous Chromosome Segregation Negative Regulation Of Cell Cycle Resolution Of Meiotic Recombination Intermediates Negative Regulation Of MAPK Cascade Mitotic Cell Cycle Process Regulation Of Phosphorus Metabolic Process Microtubule-based Process Mitotic Cell Cycle Meiotic Chromosome Segregation Meiotic Cell Cycle Regulation Of Phosphorylation Chromosome Separation Regulation Of Protein Phosphorylation Synaptonemal Complex Assembly Regulation Of Cell Cycle Phase Transition Regulation Of Mitotic Cell Cycle Synaptonemal Complex Organization Meiosis I Regulation Of Metabolic Process Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Microtubule Cytoskeleton Organization Gene Expression G2/M Transition Of Mitotic Cell Cycle Metaphase Plate Congression Spindle Organization Positive Regulation Of Glucocorticoid Receptor Signaling Pathway Meiotic Metaphase I Plate Congression Negative Regulation Of Mitochondrial DNA Replication Meiotic Spindle Midzone Assembly Establishment Of Meiotic Spindle Orientation Negative Regulation Of Metaphase/anaphase Transition Of Meiotic Cell Cycle Regulation Of Cell Cycle Process Negative Regulation Of Protein Serine/threonine Kinase Activity Cellular Component Assembly Negative Regulation Of Transferase Activity Regulation Of Protein Kinase Activity Negative Regulation Of Insulin Receptor Signaling Pathway Mitotic Nuclear Division	Inositol Biosynthetic Process Regulatory T Cell Differentiation Positive Regulation Of Isotype Switching To IgG Isotypes Regulation Of Isotype Switching To IgG Isotypes Positive Regulation Of Inflammatory Response To Antigenic Stimulus Negative Thymic T Cell Selection Cellular Response To Growth Factor Stimulus Positive Regulation Of Alpha-beta T Cell Proliferation Positive Regulation Of Interleukin-2 Biosynthetic Process Negative T Cell Selection Response To Growth Factor Inositol Metabolic Process Positive Regulation Of Viral Genome Replication Forebrain Morphogenesis Thymic T Cell Selection Lateral Ventricle Development Regulation Of Interleukin-2 Biosynthetic Process Cytokine Biosynthetic Process Positive Regulation Of Isotype Switching Regulation Of Defense Response To Virus By Virus Cytokine Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Isotype Switching Positive Regulation Of Interleukin-2 Production Positive Regulation Of Immunoglobulin Mediated Immune Response Positive Regulation Of Immunoglobulin Production Positive Regulation Of Mitotic Nuclear Division T Cell Selection Brain Morphogenesis Ventricular System Development Inositol Phosphate Metabolic Process
Tagcloud ?			attenuated autoimmune classified deficiency deficient dephosphorylated dual encephalomyelitis enhanced hairpin ikappab immune inactivation inhibiting interacted jnk mapks mkp6 negatively phosphatase remain responses ser susceptible tab1 tak1 tcr tgf upon
Tagcloud (Difference) ?			attenuated autoimmune classified deficiency deficient dephosphorylated dual encephalomyelitis enhanced hairpin ikappab immune inactivation inhibiting interacted jnk mapks mkp6 negatively phosphatase remain responses ser susceptible tab1 tak1 tcr tgf upon
Tagcloud (Intersection) ?