SPERT and MED28

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SPERT	MED28
Gene Name		spermatid associated	mediator complex subunit 28
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasmic Membrane-bounded Vesicle	Membrane Mediator Complex Cortical Actin Cytoskeleton
	Molecular Function		Actin Binding Protein Binding
	Biological Process		Transcription, DNA-templated Regulation Of Transcription, DNA-templated Stem Cell Maintenance Negative Regulation Of Smooth Muscle Cell Differentiation
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		63 interactors: ACTN1 ARHGEF40 ARMC7 C14orf105 C19orf44 C1orf109 CCDC146 CCNG1 CDC23 CEP44 CEP57L1 CEP95 CHCHD3 CHIC2 CKS1B CNNM3 CTNNAL1 DGCR6 DUSP14 DZIP1L EIF4E2 ENKD1 FAM161A FRS3 GOLGA6L2 HAUS1 KIFC3 KLC3 LATS1 LENG1 LMO1 LMO2 LMO3 MED28 METTL17 MLH1 MMAB MOS NINL PID1 PIN1 PLEKHN1 PPP1R18 RPL9 RTP5 RUNX1T1 SCNM1 SH3RF2 SYCE1 TCEANC TCEB3 TEX11 TRIM42 TSC2 TSGA10 TUBGCP4 TXLNA TXLNB ZC2HC1C ZMAT2 ZNF564 ZNF581 ZNF655	14 interactors: FYN GRB2 KLHL12 LCK MAGEA11 MED30 MED8 MED9 NF2 PRMT6 PUF60 SPERT SRC USHBP1
Entrez ID		220082	80306
HPRD ID		14856	14381
Ensembl ID		ENSG00000174015
Uniprot IDs		Q8NA61	Q9H204
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Cycle Process Cell Cycle Male Meiosis Chromosome Segregation Organelle Organization Regulation Of Cell Cycle Chromosome Segregation Negative Regulation Of Phosphorylation Negative Regulation Of Cellular Metabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cell Division Synapsis Homologous Chromosome Segregation Negative Regulation Of Cell Cycle Resolution Of Meiotic Recombination Intermediates Negative Regulation Of MAPK Cascade Mitotic Cell Cycle Process Regulation Of Phosphorus Metabolic Process Microtubule-based Process Mitotic Cell Cycle Meiotic Chromosome Segregation Meiotic Cell Cycle Regulation Of Phosphorylation Chromosome Separation Regulation Of Protein Phosphorylation Synaptonemal Complex Assembly Regulation Of Cell Cycle Phase Transition Regulation Of Mitotic Cell Cycle Synaptonemal Complex Organization Meiosis I Regulation Of Metabolic Process Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Microtubule Cytoskeleton Organization Gene Expression G2/M Transition Of Mitotic Cell Cycle Metaphase Plate Congression Spindle Organization Positive Regulation Of Glucocorticoid Receptor Signaling Pathway Meiotic Metaphase I Plate Congression Negative Regulation Of Mitochondrial DNA Replication Meiotic Spindle Midzone Assembly Establishment Of Meiotic Spindle Orientation Negative Regulation Of Metaphase/anaphase Transition Of Meiotic Cell Cycle Regulation Of Cell Cycle Process Negative Regulation Of Protein Serine/threonine Kinase Activity Cellular Component Assembly Negative Regulation Of Transferase Activity Regulation Of Protein Kinase Activity Negative Regulation Of Insulin Receptor Signaling Pathway Mitotic Nuclear Division	T Cell Costimulation Regulation Of Cell-cell Adhesion Peptidyl-tyrosine Autophosphorylation Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Platelet Activation Response To Fibroblast Growth Factor Positive Regulation Of T Cell Activation Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Homotypic Cell-cell Adhesion Neurotrophin Signaling Pathway Leukocyte Migration Viral Process Positive Regulation Of Cell-cell Adhesion Regulation Of Cell Adhesion Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of T Cell Activation Positive Regulation Of Cell Activation Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Cellular Response To Platelet-derived Growth Factor Stimulus Response To Platelet-derived Growth Factor Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell Adhesion Regulation Of Lymphocyte Activation Regulation Of Gene Expression Blood Coagulation Phosphatidylinositol-mediated Signaling Hemostasis Response To Peptide Hormone Cellular Response To Organonitrogen Compound Immune Response-regulating Signaling Pathway Regulation Of Cell Activation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Response To Peptide Fc Receptor Mediated Stimulatory Signaling Pathway Regulation Of Defense Response To Virus By Virus Negative Regulation Of Signal Transduction Regulation Of Metabolic Process Cellular Response To Growth Factor Stimulus Cellular Response To Hormone Stimulus Protein Autophosphorylation Regulation Of Body Fluid Levels Negative Regulation Of Signaling Response To Mechanical Stimulus Response To Growth Factor
Tagcloud ?			aspect blocked concomitant construct cytoskeleton dead ectopic eg exhibits exogenous grb2 interfering invasion magicin map2k1 mediator mek1 merlin metalloproteinase migration mmp2 potentiated presumably recovered reinforcing repressor rescued stimulate suppression
Tagcloud (Difference) ?			aspect blocked concomitant construct cytoskeleton dead ectopic eg exhibits exogenous grb2 interfering invasion magicin map2k1 mediator mek1 merlin metalloproteinase migration mmp2 potentiated presumably recovered reinforcing repressor rescued stimulate suppression
Tagcloud (Intersection) ?