SPERT and CKS1B

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SPERT	CKS1B
Gene Name		spermatid associated	CDC28 protein kinase regulatory subunit 1B
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasmic Membrane-bounded Vesicle	Nucleoplasm
	Molecular Function		Protein Binding Cyclin-dependent Protein Serine/threonine Kinase Regulator Activity
	Biological Process		Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Cell Proliferation Cell Division
Pathways			Cyclin D associated events in G1 SCF(Skp2)-mediated degradation of p27/p21 G1/S Transition G1 Phase Cyclin E associated events during G1/S transition SCF(Skp2)-mediated degradation of p27/p21 S Phase Cyclin A:Cdk2-associated events at S phase entry Mitotic G1-G1/S phases Cell Cycle, Mitotic
Drugs
Diseases
GWAS			Prostate cancer ( 23535732)
Protein-Protein Interactions		63 interactors: ACTN1 ARHGEF40 ARMC7 C14orf105 C19orf44 C1orf109 CCDC146 CCNG1 CDC23 CEP44 CEP57L1 CEP95 CHCHD3 CHIC2 CKS1B CNNM3 CTNNAL1 DGCR6 DUSP14 DZIP1L EIF4E2 ENKD1 FAM161A FRS3 GOLGA6L2 HAUS1 KIFC3 KLC3 LATS1 LENG1 LMO1 LMO2 LMO3 MED28 METTL17 MLH1 MMAB MOS NINL PID1 PIN1 PLEKHN1 PPP1R18 RPL9 RTP5 RUNX1T1 SCNM1 SH3RF2 SYCE1 TCEANC TCEB3 TEX11 TRIM42 TSC2 TSGA10 TUBGCP4 TXLNA TXLNB ZC2HC1C ZMAT2 ZNF564 ZNF581 ZNF655	34 interactors: ARID5A CCNA1 CCNA2 CCNB2 CDC27 CDC37 CDK1 CDK2 CDKN1B CDX4 CKS1BP7 CKS2 CUL1 DUSP1 HSP90AA1 IKZF1 KIAA0368 KRTAP10-9 KRTAP5-9 LDHB MEOX1 MIPOL1 PSMD9 REL ROPN1 SEPT3 SKP1 SKP2 SPERT SSBP1 SUMO1P1 TCF4 TRIM27 XIAP
Entrez ID		220082	1163
HPRD ID		14856	00299
Ensembl ID		ENSG00000174015	ENSG00000173207
Uniprot IDs		Q8NA61	P61024 Q5T178
PDB IDs			1BUH 1DKS 1DKT 2ASS 2AST
Enriched GO Terms of Interacting Partners?		Cell Cycle Process Cell Cycle Male Meiosis Chromosome Segregation Organelle Organization Regulation Of Cell Cycle Chromosome Segregation Negative Regulation Of Phosphorylation Negative Regulation Of Cellular Metabolic Process Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cell Division Synapsis Homologous Chromosome Segregation Negative Regulation Of Cell Cycle Resolution Of Meiotic Recombination Intermediates Negative Regulation Of MAPK Cascade Mitotic Cell Cycle Process Regulation Of Phosphorus Metabolic Process Microtubule-based Process Mitotic Cell Cycle Meiotic Chromosome Segregation Meiotic Cell Cycle Regulation Of Phosphorylation Chromosome Separation Regulation Of Protein Phosphorylation Synaptonemal Complex Assembly Regulation Of Cell Cycle Phase Transition Regulation Of Mitotic Cell Cycle Synaptonemal Complex Organization Meiosis I Regulation Of Metabolic Process Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Microtubule Cytoskeleton Organization Gene Expression G2/M Transition Of Mitotic Cell Cycle Metaphase Plate Congression Spindle Organization Positive Regulation Of Glucocorticoid Receptor Signaling Pathway Meiotic Metaphase I Plate Congression Negative Regulation Of Mitochondrial DNA Replication Meiotic Spindle Midzone Assembly Establishment Of Meiotic Spindle Orientation Negative Regulation Of Metaphase/anaphase Transition Of Meiotic Cell Cycle Regulation Of Cell Cycle Process Negative Regulation Of Protein Serine/threonine Kinase Activity Cellular Component Assembly Negative Regulation Of Transferase Activity Regulation Of Protein Kinase Activity Negative Regulation Of Insulin Receptor Signaling Pathway Mitotic Nuclear Division	Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Cell Cycle G2/M Transition Of Mitotic Cell Cycle Cell Cycle Process Regulation Of Cell Cycle Regulation Of Protein Metabolic Process Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Mitotic Cell Cycle Process G1/S Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Regulation Of Cellular Protein Metabolic Process Regulation Of Catalytic Activity Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Proteasomal Protein Catabolic Process Regulation Of Ubiquitin-protein Transferase Activity Negative Regulation Of Cell Cycle Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Positive Regulation Of Cellular Metabolic Process Regulation Of Protein Ubiquitination Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Positive Regulation Of Protein Ubiquitination Regulation Of Mitotic Cell Cycle Positive Regulation Of Metabolic Process Cell Division Positive Regulation Of Ubiquitin-protein Transferase Activity Positive Regulation Of Ligase Activity Mitotic Cell Cycle Checkpoint Regulation Of Metabolic Process Positive Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Mitotic DNA Damage Checkpoint Regulation Of Protein Kinase Activity Mitotic DNA Integrity Checkpoint Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Kinase Activity Cellular Protein Catabolic Process Positive Regulation Of Protein Catabolic Process Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Cell Cycle Checkpoint Regulation Of Cell Cycle Phase Transition Protein Catabolic Process Positive Regulation Of Protein Metabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Protein Catabolic Process
Tagcloud ?			axis biomarker cascade chemoresistance chemoresistant discoveries doi drive escape exerts gained immunoinhibitory inversely l1 l1highdrug mechanistic microrna mimic mir mt nsclc pd platinum programmed promotion sensitizes stat3 tumorigenicity worse
Tagcloud (Difference) ?			axis biomarker cascade chemoresistance chemoresistant discoveries doi drive escape exerts gained immunoinhibitory inversely l1 l1highdrug mechanistic microrna mimic mir mt nsclc pd platinum programmed promotion sensitizes stat3 tumorigenicity worse
Tagcloud (Intersection) ?