CBY2 and MMAB

Number of citations of the paper that reports this interaction (PubMedID 25910212)
47

Data Source:
BioGRID (two hybrid)

		CBY2	MMAB
Description		chibby family member 2	metabolism of cobalamin associated B
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasmic Vesicle	Mitochondrion Mitochondrial Matrix
	Molecular Function	Protein Binding Identical Protein Binding	Nucleotide Binding Protein Binding ATP Binding Corrinoid Adenosyltransferase Activity Transferase Activity Transferase Activity, Transferring Alkyl Or Aryl (other Than Methyl) Groups Cobalamin Binding
	Biological Process		Cobalamin Metabolic Process
Pathways			Defective MMAB causes MMA, cblB type Cobalamin (Cbl) metabolism
Drugs
Diseases			Methylmalonic aciduria (MMA)
GWAS			Age-related nuclear cataracts ( 33311586 24951543) Apolipoprotein A1 levels ( 32203549) Fish- and plant-related diet ( 32066663) HDL cholesterol ( 19060906 25961943 20864672 20686565 18193043) HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) HDL cholesterol levels x short total sleep time interaction (2df test) ( 31719535) High density lipoprotein cholesterol levels ( 33339817) Monocyte percentage of white cells ( 32888494) Non-oily fish consumption ( 32066663) Oily fish consumption ( 32066663) Polymyositis ( 26362759) Pork consumption ( 32066663) Red cell distribution width ( 32888494)
Interacting Genes		119 interacting genes: ACTN1 AIMP2 AIRIM ARHGEF40 ARMC7 BEX3 C19orf44 CCDC146 CCDC185 CCDC187 CCDC198 CCDC57 CCHCR1 CCNG1 CDC23 CDC37 CDK18 CDK2 CEP44 CEP55 CEP57L1 CEP95 CHCHD3 CHIC2 CIBAR1 CKS1B CNNM3 CYTH4 DGCR6 DTNB DUSP14 DZIP1L EFCAB3 EIF4E2 ELOA ENKD1 FAM161A FANCG FARS2 FBXO17 FRS3 GADD45A GADD45GIP1 GOLGA2 GOLGA6A GOLGA6L2 GRAP2 HAUS1 HSF2BP ING5 ISCU KIAA0408 KIFC3 KLC3 LATS1 LENG1 LMO1 LMO2 LMO3 LNX1 MCRS1 MED28 METTL17 MLH1 MMAB MOS NDUFA5 NEK6 NINL NME7 NTAQ1 OIP5 PID1 PIN1 PLEKHN1 POLR1C PPFIA3 PPP1R13B PPP1R18 PRPF18 PRPF31 RCOR3 RNF6 RPL9 RTP5 RUNX1T1 SCNM1 SDCBP SH3RF2 SNAPC5 SSX3 SYCE1 SYT17 TCEA2 TCEANC TCHP TEX11 TRIM42 TRIML2 TSC2 TSGA10 TSGA10IP TUBGCP4 TXK TXLNA TXLNB USHBP1 ZC2HC1C ZFYVE26 ZMAT2 ZNF250 ZNF417 ZNF564 ZNF572 ZNF581 ZNF655 ZNF688 ZNF764 ZNF785	2 interacting genes: CBY2 MTRR
Entrez ID		220082	326625
HPRD ID		14856	07398
Ensembl ID		ENSG00000174015	ENSG00000139428
Uniprot IDs		A0A140VJV5 Q8NA61	B4DHP4 Q96EY8
PDB IDs			2IDX 6D5K 6D5X 7RUT 7RUU 7RUV
Enriched GO Terms of Interacting Partners?		Protein Binding Centrosome Cytoskeleton Centriole Spindle Pole Microtubule-based Process Microtubule Organizing Center Organization Organelle Organization Cell Division Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Ciliary Basal Body Male Meiosis Chromosome Segregation Microtubule Cytoskeleton Organization Centrosome Cycle Microtubule Binding	Oxidoreductase Activity, Acting On Metal Ions, NAD Or NADP As Acceptor [methionine Synthase] Reductase (NADPH) Activity NADPH-hemoprotein Reductase Activity S-adenosylmethionine Cycle Homocysteine Catabolic Process Methionine Biosynthetic Process FMN Binding Molecular Carrier Activity Sulfur Amino Acid Catabolic Process Homocysteine Metabolic Process Cobalamin Metabolic Process NADPH Binding Folic Acid Metabolic Process Sulfur Amino Acid Biosynthetic Process S-adenosylmethionine Metabolic Process Methionine Metabolic Process Folic Acid-containing Compound Metabolic Process Pteridine-containing Compound Metabolic Process Sulfur Amino Acid Metabolic Process FAD Binding Aspartate Family Amino Acid Metabolic Process Intermediate Filament Cytoskeleton Tetrapyrrole Metabolic Process Amino Acid Biosynthetic Process Flavin Adenine Dinucleotide Binding Dicarboxylic Acid Metabolic Process Sulfur Compound Biosynthetic Process Amino Acid Catabolic Process Modified Amino Acid Metabolic Process L-amino Acid Metabolic Process Alpha-amino Acid Metabolic Process Carboxylic Acid Catabolic Process Sulfur Compound Metabolic Process Carboxylic Acid Biosynthetic Process Amino Acid Metabolic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?