EPB41 and ACTA1

Number of citations of the paper that reports this interaction (PMID 11071908)
5

Data Source:
HPRD (in vitro)

		EPB41	ACTA1
Gene Name		erythrocyte membrane protein band 4.1	actin, alpha 1, skeletal muscle
Image
Gene Ontology Annotations	Cellular Component	Nucleus Golgi Apparatus Plasma Membrane Spectrin Spectrin-associated Cytoskeleton Extrinsic Component Of Membrane Cortical Cytoskeleton Intracellular Membrane-bounded Organelle Protein Complex	Stress Fiber Extracellular Space Cytosol Striated Muscle Thin Filament Actin Filament Actin Cytoskeleton Sarcomere Extracellular Vesicular Exosome Blood Microparticle
	Molecular Function	Actin Binding Structural Constituent Of Cytoskeleton Protein Binding Calmodulin Binding 1-phosphatidylinositol Binding Spectrin Binding	Structural Constituent Of Cytoskeleton Protein Binding ATP Binding Myosin Binding ADP Binding
	Biological Process	Blood Circulation Actin Cytoskeleton Organization Cortical Actin Cytoskeleton Organization Positive Regulation Of Protein Binding	Muscle Contraction Response To Mechanical Stimulus Response To Extracellular Stimulus Response To Lithium Ion Cell Growth Muscle Filament Sliding Skeletal Muscle Thin Filament Assembly Skeletal Muscle Fiber Adaptation Response To Steroid Hormone Skeletal Muscle Fiber Development
Pathways			Striated Muscle Contraction
Drugs
Diseases
GWAS
Protein-Protein Interactions		39 interactors: ACTA1 APP BCAM C2CD2L CASK CD44 CENPJ CLNS1A CRYAB DLG1 DRD2 DRD3 EGFR EIF3G EPB42 FKBP2 GDI1 GYPC KPNA2 MACROD1 MYL1 NPPA NUMA1 PRKCB RWDD2B SEC14L1 SLC4A1 SMAD3 SPTAN1 SPTB SPTBN1 TJP2 TPM1 TUBA4A U2AF1 U2AF2 YWHAB YWHAQ ZCCHC10	107 interactors: ABL1 ABRA ACTR10 ACTR1B ADSS AFAP1 AIF1 AJUBA AMOT CCIN CCT2 CCT4 CCT5 CFL1 CLIC5 CNN1 CORO2B COTL1 CTNND1 CTTN CYFIP1 CYTH1 DHX9 DLG1 DMD DNASE1 DNMBP DTNA EGFR EPB41 EPB41L2 EPS8 FGD4 FHOD1 FSCN1 GAS2 GAS7 GC GSN HCLS1 HDAC4 HIP1R HTRA2 IQGAP1 ITGA2 ITPKA KIF23 KLHL20 LASP1 MACF1 MAP1A MIB2 MINPP1 MYL1 MYLK MYO10 MYO6 MYO7A MYO9B NEXN NR3C2 NRAP PAK1 PARVA PCYT1B PFDN1 PFN1 PHACTR1 PLD1 PPP1R9B PRKCA PRKCD PRKCE RAC1 RPS6KB1 S100A1 S100A4 SCIN SMTN SNCA SORBS1 SPRR1A SPTA1 SPTAN1 SPTBN2 TAGLN TJP1 TLN1 TMSB4X TMSB4Y TNNI1 TNNI3 TNNI3K TP53 TPM2 TPM3 TRIM55 TRIM63 TTN USP25 USP6NL UTRN VASP VAV1 VCL VIL1 XIRP1
Entrez ID		2035	58
HPRD ID		00558	00030
Ensembl ID		ENSG00000159023	ENSG00000143632
Uniprot IDs		E9PEW9 P11171 Q1WWM3 Q29RX4 Q59F12	P68133 Q5T8M7
PDB IDs		1GG3 2RQ1 3QIJ	1T44
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Component Organization Positive Regulation Of Transport Muscle System Process Cell Development Regulation Of Establishment Of Protein Localization Regulation Of Organelle Organization Muscle Contraction Axonogenesis Movement Of Cell Or Subcellular Component Axon Guidance Axon Development System Development Regulation Of Protein Localization Cellular Component Assembly Regulation Of Cellular Localization Cell Morphogenesis Involved In Neuron Differentiation Cell Differentiation Neuron Projection Morphogenesis Anatomical Structure Development Anatomical Structure Morphogenesis Regulation Of Locomotion Involved In Locomotory Behavior Negative Regulation Of Dopamine Receptor Signaling Pathway Regulation Of Cytoskeleton Organization Response To External Stimulus Cell Morphogenesis Involved In Differentiation Apoptotic Process Regulation Of Systemic Arterial Blood Pressure Regulation Of Actin Cytoskeleton Organization Programmed Cell Death Multicellular Organismal Development Muscle Filament Sliding Actin-myosin Filament Sliding Ion Homeostasis Negative Regulation Of Protein Kinase B Signaling Cell Death Death Cell Morphogenesis Neuron Projection Development Negative Regulation Of Transport Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Chemotaxis Cell Projection Morphogenesis Regulation Of Dopamine Receptor Signaling Pathway Developmental Process Regulation Of Protein Kinase B Signaling Regulation Of Protein Transport Cell Part Morphogenesis Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Cell Projection Organization	Actin Filament-based Process Actin Cytoskeleton Organization Cytoskeleton Organization Actin Filament Organization Regulation Of Cytoskeleton Organization Regulation Of Actin Cytoskeleton Organization Movement Of Cell Or Subcellular Component Regulation Of Actin Filament-based Process Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Regulation Of Cellular Component Organization Regulation Of Actin Filament Polymerization Regulation Of Organelle Organization Regulation Of Cellular Component Size Regulation Of Protein Complex Assembly Actin Filament-based Movement Muscle Contraction Muscle System Process Cell Projection Organization Organelle Organization Negative Regulation Of Protein Polymerization Negative Regulation Of Actin Filament Polymerization Positive Regulation Of Cytoskeleton Organization Cellular Component Assembly Developmental Process Anatomical Structure Morphogenesis Anatomical Structure Development Negative Regulation Of Protein Complex Assembly System Development Actin-mediated Cell Contraction Response To Wounding Locomotion Cell Development Response To External Stimulus Cell Differentiation Wound Healing Multicellular Organismal Development Cell Morphogenesis Negative Regulation Of Cytoskeleton Organization Positive Regulation Of Cellular Component Biogenesis Tissue Development Cell Projection Morphogenesis Chemotaxis Positive Regulation Of Organelle Organization Cell Part Morphogenesis Neuron Development Actin Polymerization Or Depolymerization Blood Coagulation Hemostasis Cell Junction Assembly
Tagcloud ?		ank1 antiglobulin appointment bilirubin cared cytoskeletal cytoskeleton damaged delays discharged e508k epb42 erythrocyte incompatibility kernicterus neurologic newborn parent persisted phototherapy retesting return silico slc4a1 smear spherocytes spta1 sptb ugt1a1	annotation assembled biomedical contigs cox1 discover eef1a1 eef1g ends est ests expand gluconeogenesis libraries livestock loin normalized ontology pfam pig pituitary porcine singletons sla slc25a6 susflecks tags transducin wd40
Tagcloud (Difference) ?		ank1 antiglobulin appointment bilirubin cared cytoskeletal cytoskeleton damaged delays discharged e508k epb42 erythrocyte incompatibility kernicterus neurologic newborn parent persisted phototherapy retesting return silico slc4a1 smear spherocytes spta1 sptb ugt1a1	annotation assembled biomedical contigs cox1 discover eef1a1 eef1g ends est ests expand gluconeogenesis libraries livestock loin normalized ontology pfam pig pituitary porcine singletons sla slc25a6 susflecks tags transducin wd40
Tagcloud (Intersection) ?