EPB41 and SPTBN1

Number of citations of the paper that reports this interaction (PMID 12901833)
5

Data Source:
HPRD (in vitro)

		EPB41	SPTBN1
Gene Name		erythrocyte membrane protein band 4.1	spectrin, beta, non-erythrocytic 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Golgi Apparatus Plasma Membrane Spectrin Spectrin-associated Cytoskeleton Extrinsic Component Of Membrane Cortical Cytoskeleton Intracellular Membrane-bounded Organelle Protein Complex	Nucleolus Cytoplasm Cytosol Spectrin Spectrin-associated Cytoskeleton Axolemma M Band Cuticular Plate Protein Complex Extracellular Vesicular Exosome
	Molecular Function	Actin Binding Structural Constituent Of Cytoskeleton Protein Binding Calmodulin Binding 1-phosphatidylinositol Binding Spectrin Binding	Actin Binding Structural Constituent Of Cytoskeleton Protein Binding Calmodulin Binding Phospholipid Binding Ankyrin Binding Protein Complex Binding Poly(A) RNA Binding
	Biological Process	Blood Circulation Actin Cytoskeleton Organization Cortical Actin Cytoskeleton Organization Positive Regulation Of Protein Binding	Mitotic Cytokinesis Plasma Membrane Organization Common-partner SMAD Protein Phosphorylation SMAD Protein Import Into Nucleus Axon Guidance Golgi To Plasma Membrane Protein Transport Actin Filament Capping Membrane Assembly Protein Targeting To Plasma Membrane
Pathways			Interaction between L1 and Ankyrins Axon guidance Nephrin interactions L1CAM interactions NCAM signaling for neurite out-growth
Drugs
Diseases
GWAS			Bone mineral density ( 22504420) Bone mineral density (spine) ( 19079262 19801982 18445777) Myopia (pathological) ( 22685421)
Protein-Protein Interactions		39 interactors: ACTA1 APP BCAM C2CD2L CASK CD44 CENPJ CLNS1A CRYAB DLG1 DRD2 DRD3 EGFR EIF3G EPB42 FKBP2 GDI1 GYPC KPNA2 MACROD1 MYL1 NPPA NUMA1 PRKCB RWDD2B SEC14L1 SLC4A1 SMAD3 SPTAN1 SPTB SPTBN1 TJP2 TPM1 TUBA4A U2AF1 U2AF2 YWHAB YWHAQ ZCCHC10	39 interactors: ACTR1A ANK2 APC ATF7IP CAPN1 CDC5L CEP63 CPNE1 CPNE4 CSNK2A1 CTNNA1 DISC1 EPB41 EPB41L3 GRB2 GRIA2 MAPK14 MEF2C NF2 PACSIN1 PDE4D PJA1 PLCB1 PLEKHA5 PRKACA PYGO1 RINT1 SH3BP5 SMAD3 SMAD4 SMAD9 SNCA SPTAN1 SREBF2 STAT1 TNIK TRAF3IP1 YWHAG ZNF512B
Entrez ID		2035	6711
HPRD ID		00558	01683
Ensembl ID		ENSG00000159023	ENSG00000115306
Uniprot IDs		E9PEW9 P11171 Q1WWM3 Q29RX4 Q59F12	B2ZZ89 Q01082
PDB IDs		1GG3 2RQ1 3QIJ	1AA2 1BKR 3EDV
Enriched GO Terms of Interacting Partners?		Regulation Of Cellular Component Organization Positive Regulation Of Transport Muscle System Process Cell Development Regulation Of Establishment Of Protein Localization Regulation Of Organelle Organization Muscle Contraction Axonogenesis Movement Of Cell Or Subcellular Component Axon Guidance Axon Development System Development Regulation Of Protein Localization Cellular Component Assembly Regulation Of Cellular Localization Cell Morphogenesis Involved In Neuron Differentiation Cell Differentiation Neuron Projection Morphogenesis Anatomical Structure Development Anatomical Structure Morphogenesis Regulation Of Locomotion Involved In Locomotory Behavior Negative Regulation Of Dopamine Receptor Signaling Pathway Regulation Of Cytoskeleton Organization Response To External Stimulus Cell Morphogenesis Involved In Differentiation Apoptotic Process Regulation Of Systemic Arterial Blood Pressure Regulation Of Actin Cytoskeleton Organization Programmed Cell Death Multicellular Organismal Development Muscle Filament Sliding Actin-myosin Filament Sliding Ion Homeostasis Negative Regulation Of Protein Kinase B Signaling Cell Death Death Cell Morphogenesis Neuron Projection Development Negative Regulation Of Transport Positive Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Chemotaxis Cell Projection Morphogenesis Regulation Of Dopamine Receptor Signaling Pathway Developmental Process Regulation Of Protein Kinase B Signaling Regulation Of Protein Transport Cell Part Morphogenesis Adenylate Cyclase-inhibiting Dopamine Receptor Signaling Pathway Cell Projection Organization	Regulation Of Cellular Component Organization System Development Intracellular Signal Transduction Nervous System Development Regulation Of Cellular Localization Cell Differentiation Positive Regulation Of Cell Differentiation Regulation Of Cell Differentiation Regulation Of Phosphorylation Regulation Of Signal Transduction Multicellular Organismal Development Anatomical Structure Development Cell-cell Junction Organization Regulation Of Intracellular Transport Developmental Process Regulation Of Phosphorus Metabolic Process Negative Regulation Of Protein Phosphorylation Positive Regulation Of Signal Transduction Regulation Of Signaling Regulation Of Protein Phosphorylation Neurogenesis Negative Regulation Of Phosphorylation Apoptotic Process Signaling Anatomical Structure Morphogenesis Negative Regulation Of Cellular Metabolic Process Cell Development Organelle Organization Programmed Cell Death Cell Communication Generation Of Neurons Kidney Development Cell Death Cell Morphogenesis Death Regulation Of Protein Metabolic Process Cell-cell Junction Assembly Epithelium Development Cellular Response To Organonitrogen Compound Renal System Development Cell Activation Organ Development Regulation Of Cellular Protein Metabolic Process Enzyme Linked Receptor Protein Signaling Pathway Negative Regulation Of Protein Metabolic Process Cell Projection Organization Regulation Of Organelle Organization Positive Regulation Of Metabolic Process G2/M Transition Of Mitotic Cell Cycle Neuron Development
Tagcloud ?		ank1 antiglobulin appointment bilirubin cared cytoskeletal cytoskeleton damaged delays discharged e508k epb42 erythrocyte incompatibility kernicterus neurologic newborn parent persisted phototherapy retesting return silico slc4a1 smear spherocytes spta1 sptb ugt1a1	adipocyte analyzing classified cytoskeletal differentially exposed exposure fact fatty insights k18 keratin mediating morphogenesis nicotine obstructive osf3 peroxiredoxin phosphoprotein phosphoproteins phosphoproteomic regeneration semi sixteen smoke sought spectrin spt16 tobacco
Tagcloud (Difference) ?		ank1 antiglobulin appointment bilirubin cared cytoskeleton damaged delays discharged e508k epb42 erythrocyte incompatibility kernicterus neurologic newborn parent persisted phototherapy retesting return silico slc4a1 smear spherocytes spta1 sptb ugt1a1	adipocyte analyzing classified differentially exposed exposure fact fatty insights k18 keratin mediating morphogenesis nicotine obstructive osf3 peroxiredoxin phosphoprotein phosphoproteins phosphoproteomic regeneration semi sixteen smoke sought spectrin spt16 tobacco
Tagcloud (Intersection) ?		cytoskeletal