SREK1 and HNRNPU

Number of citations of the paper that reports this interaction (PMID 14559993)
9

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		SREK1	HNRNPU
Gene Name		splicing regulatory glutamine/lysine-rich protein 1	heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A)
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Spliceosomal Complex	Nucleus Nucleoplasm Cell Surface Membrane Ribonucleoprotein Complex Cytoplasmic Ribonucleoprotein Granule CRD-mediated MRNA Stability Complex Catalytic Step 2 Spliceosome
	Molecular Function	Nucleotide Binding Poly(A) RNA Binding	Core Promoter Binding DNA Binding RNA Binding Protein Binding ATP Binding Poly(A) RNA Binding
	Biological Process	MRNA Processing RNA Splicing	MRNA Splicing, Via Spliceosome Osteoblast Differentiation RNA Processing RNA Splicing Gene Expression Circadian Regulation Of Gene Expression CRD-mediated MRNA Stabilization
Pathways			Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		55 interactors: CD8A CSNK2A1 DDX17 DDX39B DDX3X DGKA DGKD EFTUD2 ELAVL1 GNB2L1 HNRNPA1 HNRNPA2B1 HNRNPA3 HNRNPC HNRNPD HNRNPH1 HNRNPK HNRNPU ILF2 MDM2 NCL NPM1 PABPC1 PABPC4 PARP1 PIN1 RBM10 RBMX SAFB SF3A3 SF3B3 SFPQ SH3GLB2 SNRPD1 SNRPD3 SRPK1 SRPK2 SRPK3 SRSF1 SRSF10 SRSF11 SRSF2 SRSF3 SRSF4 SRSF5 SRSF6 SRSF7 SRSF8 SSRP1 SUPT16H TARBP1 THRAP3 TRA2B YBX1 ZRANB2	35 interactors: ACTB BTRC CASP3 CD5 CDKN2A CR2 ELL EP300 ERG GAS7 GRIN1 GRIN2D GTF2H1 HNRNPD HNRNPH3 IL7R KAT2B NDN NDRG1 NEDD4 NR3C1 PIN1 POLR2A POU3F4 PRMT1 PRPF40A PTPN11 SMN1 SREK1 STAU1 SYK TCERG1 WBP4 YAP1 ZNF689
Entrez ID		140890	3192
HPRD ID		18043	04185
Ensembl ID		ENSG00000153914	ENSG00000153187
Uniprot IDs		E5RFV3 Q8WXA9	Q00839 Q96BA7
PDB IDs			1ZRJ
Enriched GO Terms of Interacting Partners?		RNA Splicing RNA Processing MRNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions MRNA Metabolic Process Gene Expression RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of MRNA Processing Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Splicing RNA Export From Nucleus Termination Of RNA Polymerase II Transcription RNA Transport MRNA Export From Nucleus RNA Localization MRNA 3'-end Processing Nuclear Export MRNA Transport Cellular Metabolic Process RNA 3'-end Processing DNA-templated Transcription, Termination Ribonucleoprotein Complex Assembly Regulation Of MRNA Stability Regulation Of RNA Stability Nucleocytoplasmic Transport Nuclear Transport Spliceosomal Complex Assembly Regulation Of Gene Expression Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Splicing MRNA Stabilization Regulation Of RNA Metabolic Process Positive Regulation Of Gene Expression Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Metabolic Process Ribonucleoprotein Complex Biogenesis Transcription, DNA-templated Posttranscriptional Regulation Of Gene Expression RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Metabolic Process Cytoplasmic Transport Positive Regulation Of Cellular Biosynthetic Process	RNA Metabolic Process Developmental Process Gene Expression Regulation Of Cell Cycle Anatomical Structure Development Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Viral Process MRNA Processing Multicellular Organismal Development Cell Differentiation Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of RNA Metabolic Process RNA Splicing Positive Regulation Of Viral Transcription Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process System Development MRNA Metabolic Process Positive Regulation Of Gene Expression Viral Process Positive Regulation Of Cellular Metabolic Process Signal Transduction RNA Processing Positive Regulation Of Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Transcription, DNA-templated Regulation Of Cellular Process RNA Biosynthetic Process Cellular Response To Stimulus Cellular Nitrogen Compound Metabolic Process Anatomical Structure Morphogenesis Regulation Of Viral Process Transcription From RNA Polymerase II Promoter Regulation Of Viral Transcription Regulation Of T Cell Activation Signaling Transcription Initiation From RNA Polymerase II Promoter Cell Communication Regulation Of Metabolic Process Cellular Metabolic Process N-terminal Peptidyl-lysine Acetylation Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Cell Surface Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process
Tagcloud ?			17p13 1q21 1q44 2q23 2q31 agilent annotations asd autism backgrounds cgh cnv cnvs disabilities dissect encephalopathy epileptic exome expand hallux implicates infantile intellectual lissencephaly mbd5 microcephaly pafah1b1 pathogenicity spasms
Tagcloud (Difference) ?			17p13 1q21 1q44 2q23 2q31 agilent annotations asd autism backgrounds cgh cnv cnvs disabilities dissect encephalopathy epileptic exome expand hallux implicates infantile intellectual lissencephaly mbd5 microcephaly pafah1b1 pathogenicity spasms
Tagcloud (Intersection) ?