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SREK1 and EFTUD2
Number of citations of the paper that reports this interaction (PMID
14559993
)
9
Data Source:
HPRD
(in vivo, two hybrid, in vitro)
SREK1
EFTUD2
Gene Name
splicing regulatory glutamine/lysine-rich protein 1
elongation factor Tu GTP binding domain containing 2
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Spliceosomal Complex
Nucleoplasm
Spliceosomal Complex
Cytoplasm
Cajal Body
Membrane
Nuclear Speck
Catalytic Step 2 Spliceosome
Molecular Function
Nucleotide Binding
Poly(A) RNA Binding
GTPase Activity
Protein Binding
GTP Binding
Poly(A) RNA Binding
Biological Process
MRNA Processing
RNA Splicing
MRNA Splicing, Via Spliceosome
MRNA Processing
RNA Splicing
Gene Expression
Pathways
Processing of Capped Intron-Containing Pre-mRNA
mRNA Splicing
mRNA Splicing - Minor Pathway
mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions
55 interactors:
CD8A
CSNK2A1
DDX17
DDX39B
DDX3X
DGKA
DGKD
EFTUD2
ELAVL1
GNB2L1
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPC
HNRNPD
HNRNPH1
HNRNPK
HNRNPU
ILF2
MDM2
NCL
NPM1
PABPC1
PABPC4
PARP1
PIN1
RBM10
RBMX
SAFB
SF3A3
SF3B3
SFPQ
SH3GLB2
SNRPD1
SNRPD3
SRPK1
SRPK2
SRPK3
SRSF1
SRSF10
SRSF11
SRSF2
SRSF3
SRSF4
SRSF5
SRSF6
SRSF7
SRSF8
SSRP1
SUPT16H
TARBP1
THRAP3
TRA2B
YBX1
ZRANB2
16 interactors:
ARPC3
CYFIP1
GOLM1
GSK3B
HINFP
HSPB1
LSM8
PIN1
PRPF6
PRPF8
SF1
SF3B3
SF3B4
SNRNP40
SREK1
WBP4
Entrez ID
140890
9343
HPRD ID
18043
04869
Ensembl ID
ENSG00000153914
ENSG00000108883
Uniprot IDs
E5RFV3
Q8WXA9
B3KX19
B4DMC0
K7EJ81
Q15029
PDB IDs
Enriched GO Terms of Interacting Partners
?
RNA Splicing
RNA Processing
MRNA Processing
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
MRNA Metabolic Process
Gene Expression
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Regulation Of MRNA Processing
Regulation Of MRNA Splicing, Via Spliceosome
Regulation Of RNA Splicing
RNA Export From Nucleus
Termination Of RNA Polymerase II Transcription
RNA Transport
MRNA Export From Nucleus
RNA Localization
MRNA 3'-end Processing
Nuclear Export
MRNA Transport
Cellular Metabolic Process
RNA 3'-end Processing
DNA-templated Transcription, Termination
Ribonucleoprotein Complex Assembly
Regulation Of MRNA Stability
Regulation Of RNA Stability
Nucleocytoplasmic Transport
Nuclear Transport
Spliceosomal Complex Assembly
Regulation Of Gene Expression
Negative Regulation Of MRNA Splicing, Via Spliceosome
Negative Regulation Of RNA Splicing
MRNA Stabilization
Regulation Of RNA Metabolic Process
Positive Regulation Of Gene Expression
Transcription From RNA Polymerase II Promoter
Regulation Of Nitrogen Compound Metabolic Process
Metabolic Process
Ribonucleoprotein Complex Biogenesis
Transcription, DNA-templated
Posttranscriptional Regulation Of Gene Expression
RNA Biosynthetic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Metabolic Process
Cytoplasmic Transport
Positive Regulation Of Cellular Biosynthetic Process
RNA Splicing
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
MRNA Processing
MRNA Metabolic Process
RNA Processing
Gene Expression
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Spliceosomal Tri-snRNP Complex Assembly
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Ribonucleoprotein Complex Assembly
Spliceosomal SnRNP Assembly
Positive Regulation Of Cellular Metabolic Process
Spliceosomal Complex Assembly
Ribonucleoprotein Complex Biogenesis
Negative Regulation Of Type B Pancreatic Cell Development
Superior Temporal Gyrus Development
Re-entry Into Mitotic Cell Cycle
Negative Regulation Of Neuron Maturation
Negative Regulation Of Phosphorylation
Positive Regulation Of Organelle Organization
Positive Regulation Of Macromolecule Biosynthetic Process
Negative Regulation Of Intracellular Signal Transduction
Positive Regulation Of Gene Expression
Regulation Of Organelle Organization
Hypermethylation Of CpG Island
Primary Sex Determination
Positive Regulation Of Endothelial Cell Chemotaxis By VEGF-activated Vascular Endothelial Growth Factor Receptor Signaling Pathway
Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Apoptotic Process
Positive Regulation Of Cellular Biosynthetic Process
MRNA 3'-splice Site Recognition
Positive Regulation Of Cell Migration By Vascular Endothelial Growth Factor Signaling Pathway
Cellular Response To Interleukin-3
Negative Regulation Of Protein Serine/threonine Kinase Activity
Negative Regulation Of Female Gonad Development
Positive Regulation Of Metabolic Process
Negative Regulation Of Glycogen (starch) Synthase Activity
Regulation Of Neuron Maturation
Axonogenesis
Negative Regulation Of MAPK Cascade
Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation
Protein Localization To Microtubule
Positive Regulation Of Actin Nucleation
Negative Regulation Of Dendrite Morphogenesis
Positive Regulation Of Endothelial Cell Chemotaxis
Positive Regulation Of Protein Complex Assembly
Tagcloud
?
3k36me3
antagonizing
arranged
bromo
bs69
called
chromatin
connects
decorated
depends
h3k36me3
identifies
intron
ir
modalities
phd
pwwp
reader
recognizes
remarkably
retention
reveals
snrnp
spliceosome
splicing
tandemly
trimethylation
u5
zmynd11
Tagcloud (Difference)
?
3k36me3
antagonizing
arranged
bromo
bs69
called
chromatin
connects
decorated
depends
h3k36me3
identifies
intron
ir
modalities
phd
pwwp
reader
recognizes
remarkably
retention
reveals
snrnp
spliceosome
splicing
tandemly
trimethylation
u5
zmynd11
Tagcloud (Intersection)
?