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SREK1 and GNB2L1
Number of citations of the paper that reports this interaction (PMID
14559993
)
9
Data Source:
HPRD
(in vivo, in vitro, two hybrid)
SREK1
GNB2L1
Gene Name
splicing regulatory glutamine/lysine-rich protein 1
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Spliceosomal Complex
Phagocytic Cup
Nucleus
Cytoplasm
Mitochondrion
Cytosol
Cytoskeleton
Small Ribosomal Subunit
Dendrite
Midbody
Neuronal Cell Body
Perikaryon
Perinuclear Region Of Cytoplasm
Extracellular Vesicular Exosome
Molecular Function
Nucleotide Binding
Poly(A) RNA Binding
Protein Kinase C Binding
Receptor Binding
Protein Binding
Ion Channel Inhibitor Activity
Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process
Enzyme Binding
Protein Phosphatase Binding
Protein Tyrosine Kinase Inhibitor Activity
Receptor Tyrosine Kinase Binding
Protein Complex Scaffold
SH2 Domain Binding
Protein Homodimerization Activity
Poly(A) RNA Binding
Biological Process
MRNA Processing
RNA Splicing
Osteoblast Differentiation
Positive Regulation Of Protein Phosphorylation
Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process
Cell Cycle
Gastrulation
Negative Regulation Of Gene Expression
Viral Process
Negative Regulation Of Translation
Negative Regulation Of Wnt Signaling Pathway
Negative Regulation Of Cell Growth
Positive Regulation Of Cell Migration
Positive Regulation Of CAMP Catabolic Process
Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process
Positive Regulation Of Protein Homooligomerization
Regulation Of Protein Localization
Positive Regulation Of Apoptotic Process
Positive Regulation Of GTPase Activity
Rhythmic Process
Negative Regulation Of Phagocytosis
Regulation Of Cell Division
Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity
Regulation Of Cell Cycle
Negative Regulation Of Protein Kinase B Signaling
Positive Regulation Of Mitochondrial Depolarization
Negative Regulation Of Protein Tyrosine Kinase Activity
Regulation Of Establishment Of Protein Localization To Plasma Membrane
Negative Regulation Of Hydrogen Peroxide-induced Neuron Death
Regulation Of Establishment Of Cell Polarity
Positive Regulation Of Gastrulation
Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions
55 interactors:
CD8A
CSNK2A1
DDX17
DDX39B
DDX3X
DGKA
DGKD
EFTUD2
ELAVL1
GNB2L1
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPC
HNRNPD
HNRNPH1
HNRNPK
HNRNPU
ILF2
MDM2
NCL
NPM1
PABPC1
PABPC4
PARP1
PIN1
RBM10
RBMX
SAFB
SF3A3
SF3B3
SFPQ
SH3GLB2
SNRPD1
SNRPD3
SRPK1
SRPK2
SRPK3
SRSF1
SRSF10
SRSF11
SRSF2
SRSF3
SRSF4
SRSF5
SRSF6
SRSF7
SRSF8
SSRP1
SUPT16H
TARBP1
THRAP3
TRA2B
YBX1
ZRANB2
86 interactors:
ADH1B
ADRB2
AGTRAP
AR
AURKB
BCL2L11
CCNA1
CDKN1A
CHERP
CSF2RB
DDX19B
DGCR14
DNM1
DYNLL1
EIF6
EPOR
FBXW7
FYN
GABRB3
GNB1
GOLM1
GRAP2
GRIN2B
HABP4
HIF1A
HNRNPH2
IFNAR1
IFNAR2
IFNR
IGF1R
IK
IL2RB
IL4R
IL7R
INSR
ITGB1
ITGB2
ITGB5
ITGB7
JAK1
LARP4B
LRP12
MAPK6
MKRN2
NFATC1
NR3C1
NSMAF
PABPC1
PDE4D
PLCG1
PLEC
PRKAB2
PRKCA
PRKCB
PRKCD
PRKCE
PRKD1
PRPF31
PTN
PTOV1
PTPRM
RASA1
RASA3
RB1
RHOA
SAT1
SLC27A6
SLC6A3
SRC
SREK1
ST7
STAT1
STAT3
SUMO4
SYT1
TARDBP
TBXA2R
TCEB1
TCEB2
TNFRSF1A
TP63
TP73
TSC22D4
TUBB
TYK2
WDR83
Entrez ID
140890
10399
HPRD ID
18043
01503
Ensembl ID
ENSG00000153914
ENSG00000204628
Uniprot IDs
E5RFV3
Q8WXA9
E9KL35
P63244
PDB IDs
3J3A
4AOW
Enriched GO Terms of Interacting Partners
?
RNA Splicing
RNA Processing
MRNA Processing
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
MRNA Metabolic Process
Gene Expression
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Regulation Of MRNA Processing
Regulation Of MRNA Splicing, Via Spliceosome
Regulation Of RNA Splicing
RNA Export From Nucleus
Termination Of RNA Polymerase II Transcription
RNA Transport
MRNA Export From Nucleus
RNA Localization
MRNA 3'-end Processing
Nuclear Export
MRNA Transport
Cellular Metabolic Process
RNA 3'-end Processing
DNA-templated Transcription, Termination
Ribonucleoprotein Complex Assembly
Regulation Of MRNA Stability
Regulation Of RNA Stability
Nucleocytoplasmic Transport
Nuclear Transport
Spliceosomal Complex Assembly
Regulation Of Gene Expression
Negative Regulation Of MRNA Splicing, Via Spliceosome
Negative Regulation Of RNA Splicing
MRNA Stabilization
Regulation Of RNA Metabolic Process
Positive Regulation Of Gene Expression
Transcription From RNA Polymerase II Promoter
Regulation Of Nitrogen Compound Metabolic Process
Metabolic Process
Ribonucleoprotein Complex Biogenesis
Transcription, DNA-templated
Posttranscriptional Regulation Of Gene Expression
RNA Biosynthetic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Metabolic Process
Cytoplasmic Transport
Positive Regulation Of Cellular Biosynthetic Process
Signaling
Cell Communication
Cellular Response To Stimulus
Signal Transduction
Response To Stimulus
Cell Surface Receptor Signaling Pathway
Cellular Response To Organic Substance
Intracellular Signal Transduction
Response To Organic Substance
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Enzyme Linked Receptor Protein Signaling Pathway
Regulation Of Signaling
Regulation Of Signal Transduction
Response To External Stimulus
Defense Response
Viral Process
Response To Stress
Immune System Process
Regulation Of Immune Response
Regulation Of Body Fluid Levels
Regulation Of Cell Proliferation
Regulation Of Immune System Process
Response To Abiotic Stimulus
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Regulation Of Protein Localization
Positive Regulation Of Signal Transduction
Regulation Of Cellular Localization
Response To Cytokine
Regulation Of Cell Death
Regulation Of Cellular Process
Cytokine-mediated Signaling Pathway
Cellular Response To Cytokine Stimulus
Platelet Activation
Innate Immune Response
Immune Response
Regulation Of Phosphorylation
Blood Coagulation
Regulation Of Apoptotic Process
Hemostasis
Regulation Of Protein Phosphorylation
Positive Regulation Of Metabolic Process
Positive Regulation Of Cellular Biosynthetic Process
Positive Regulation Of Cell Cycle
Positive Regulation Of Transport
Peptidyl-tyrosine Autophosphorylation
Cellular Process
Neurotrophin TRK Receptor Signaling Pathway
Developmental Process
Regulation Of Angiogenesis
Positive Regulation Of Cellular Metabolic Process
Tagcloud
?
aiming
aip
alignment
boar
brms1
chordc1
clues
cops6
csde1
csfv
ddx5
domestic
fever
hemorrhagic
hspa8
interactive
metap2
nav1
ncbi
ns5a
phf5a
polr1c
ppp2r3c
psmc3
suvec
swine
tmed10
tmem70
y2h
Tagcloud (Difference)
?
aiming
aip
alignment
boar
brms1
chordc1
clues
cops6
csde1
csfv
ddx5
domestic
fever
hemorrhagic
hspa8
interactive
metap2
nav1
ncbi
ns5a
phf5a
polr1c
ppp2r3c
psmc3
suvec
swine
tmed10
tmem70
y2h
Tagcloud (Intersection)
?