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SREK1 and PABPC4
Number of citations of the paper that reports this interaction (PMID
14559993
)
9
Data Source:
HPRD
(in vitro, in vivo, two hybrid)
SREK1
PABPC4
Gene Name
splicing regulatory glutamine/lysine-rich protein 1
poly(A) binding protein, cytoplasmic 4 (inducible form)
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleoplasm
Spliceosomal Complex
Nucleus
Cytoplasm
Cytoplasmic Stress Granule
Ribonucleoprotein Complex
Molecular Function
Nucleotide Binding
Poly(A) RNA Binding
Nucleotide Binding
Protein Binding
Poly(A) Binding
Poly(U) RNA Binding
Poly(C) RNA Binding
Poly(A) RNA Binding
Biological Process
MRNA Processing
RNA Splicing
RNA Processing
RNA Catabolic Process
Translation
Blood Coagulation
Pathways
Drugs
Diseases
GWAS
C-reactive protein (
21300955
)
HDL cholesterol (
20686565
)
Protein-Protein Interactions
55 interactors:
CD8A
CSNK2A1
DDX17
DDX39B
DDX3X
DGKA
DGKD
EFTUD2
ELAVL1
GNB2L1
HNRNPA1
HNRNPA2B1
HNRNPA3
HNRNPC
HNRNPD
HNRNPH1
HNRNPK
HNRNPU
ILF2
MDM2
NCL
NPM1
PABPC1
PABPC4
PARP1
PIN1
RBM10
RBMX
SAFB
SF3A3
SF3B3
SFPQ
SH3GLB2
SNRPD1
SNRPD3
SRPK1
SRPK2
SRPK3
SRSF1
SRSF10
SRSF11
SRSF2
SRSF3
SRSF4
SRSF5
SRSF6
SRSF7
SRSF8
SSRP1
SUPT16H
TARBP1
THRAP3
TRA2B
YBX1
ZRANB2
14 interactors:
EEF1A1
GDF9
HAP1
IL7R
MED31
PHLDA1
RIF1
SETDB1
SMAD9
SREK1
SRPK2
UBC
XRN1
YWHAQ
Entrez ID
140890
8761
HPRD ID
18043
04557
Ensembl ID
ENSG00000153914
ENSG00000090621
Uniprot IDs
E5RFV3
Q8WXA9
B1ANR0
Q13310
PDB IDs
Enriched GO Terms of Interacting Partners
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RNA Splicing
RNA Processing
MRNA Processing
MRNA Splicing, Via Spliceosome
RNA Splicing, Via Transesterification Reactions
MRNA Metabolic Process
Gene Expression
RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Cellular Nitrogen Compound Metabolic Process
Nitrogen Compound Metabolic Process
Regulation Of MRNA Processing
Regulation Of MRNA Splicing, Via Spliceosome
Regulation Of RNA Splicing
RNA Export From Nucleus
Termination Of RNA Polymerase II Transcription
RNA Transport
MRNA Export From Nucleus
RNA Localization
MRNA 3'-end Processing
Nuclear Export
MRNA Transport
Cellular Metabolic Process
RNA 3'-end Processing
DNA-templated Transcription, Termination
Ribonucleoprotein Complex Assembly
Regulation Of MRNA Stability
Regulation Of RNA Stability
Nucleocytoplasmic Transport
Nuclear Transport
Spliceosomal Complex Assembly
Regulation Of Gene Expression
Negative Regulation Of MRNA Splicing, Via Spliceosome
Negative Regulation Of RNA Splicing
MRNA Stabilization
Regulation Of RNA Metabolic Process
Positive Regulation Of Gene Expression
Transcription From RNA Polymerase II Promoter
Regulation Of Nitrogen Compound Metabolic Process
Metabolic Process
Ribonucleoprotein Complex Biogenesis
Transcription, DNA-templated
Posttranscriptional Regulation Of Gene Expression
RNA Biosynthetic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Regulation Of Metabolic Process
Cytoplasmic Transport
Positive Regulation Of Cellular Biosynthetic Process
RNA Metabolic Process
Gene Expression
Regulation Of Gene Expression
Regulation Of Nitrogen Compound Metabolic Process
Cellular Response To Growth Factor Stimulus
Response To Growth Factor
Regulation Of RNA Metabolic Process
Nucleobase-containing Compound Metabolic Process
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Anatomical Structure Development
Cellular Nitrogen Compound Metabolic Process
Transforming Growth Factor Beta Receptor Signaling Pathway
Regulation Of Apoptotic Process
Regulation Of Cell Death
Transcription, DNA-templated
Cellular Response To Transforming Growth Factor Beta Stimulus
Regulation Of Transcription, DNA-templated
Developmental Process
Nitrogen Compound Metabolic Process
Response To Transforming Growth Factor Beta
Regulation Of Nucleic Acid-templated Transcription
RNA Biosynthetic Process
Regulation Of RNA Biosynthetic Process
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Cellular Macromolecule Biosynthetic Process
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Positive Regulation Of Cell Death
Multicellular Organismal Development
Regulation Of Metabolic Process
Macromolecule Biosynthetic Process
Cellular Response To Organic Substance
Positive Regulation Of Cell Cycle
Nuclear Speck Organization
Positive Regulation Of Neurotrophin Production
Positive Regulation Of Nonmotile Primary Cilium Assembly
FasL Biosynthetic Process
Organ Development
Brain Development
Regulation Of Epidermal Growth Factor Receptor Signaling Pathway
System Development
BMP Signaling Pathway
Head Development
Regulation Of ERBB Signaling Pathway
Midbrain Development
Interleukin-7-mediated Signaling Pathway
Oocyte Growth
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Cilium Assembly
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